Search Results - "Charchar, Fadi"

Wake up and enjoy the coffee without worrying about your blood pressure by Charchar, Fadi J

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Epigenetic Modifications in Essential Hypertension by Wise, Ingrid A, Charchar, Fadi J

“…Essential hypertension (EH) is a complex, polygenic condition with no single causative agent. Despite advances in our understanding of the pathophysiology of…”
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Establishment of sex difference in circulating uric acid is associated with higher testosterone and lower sex hormone-binding globulin in adolescent boys by Wang, Yutang, Charchar, Fadi J.

“…Men have higher circulating levels of uric acid than women. This sex difference is suspected to be a result of suppressive effects of estradiol on uric acid…”
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2020 International Society of Hypertension Global Hypertension Practice Guidelines by Unger, Thomas, Borghi, Claudio, Charchar, Fadi, Khan, Nadia A., Poulter, Neil R., Prabhakaran, Dorairaj, Ramirez, Agustin, Schlaich, Markus, Stergiou, George S., Tomaszewski, Maciej, Wainford, Richard D., Williams, Bryan, Schutte, Aletta E.

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2020 International Society of Hypertension global hypertension practice guidelines by Unger, Thomas, Borghi, Claudio, Charchar, Fadi, Khan, Nadia A., Poulter, Neil R., Prabhakaran, Dorairaj, Ramirez, Agustin, Schlaich, Markus, Stergiou, George S., Tomaszewski, Maciej, Wainford, Richard D., Williams, Bryan, Schutte, Aletta E.

“…Document reviewers: Hind Beheiry (Sudan), Irina Chazova (Russia), Albertino Damasceno (Mozambique), Anna Dominiczak (UK), Anastase Dzudie (Cameroon), Stephen…”
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Lifestyle management of hypertension: International Society of Hypertension position paper endorsed by the World Hypertension League and European Society of Hypertension by Charchar, Fadi J, Prestes, Priscilla R, Mills, Charlotte, Ching, Siew Mooi, Neupane, Dinesh, Marques, Francine Z, Sharman, James E, Vogt, Liffert, Burrell, Louise M, Korostovtseva, Lyudmila, Zec, Manja, Patil, Mansi, Schultz, Martin G, Wallen, Matthew P, Renna, Nicolás F, Islam, Sheikh Mohammed Shariful, Hiremath, Swapnil, Gyeltshen, Tshewang, Chia, Yook-Chin, Gupta, Abhinav, Schutte, Aletta E, Klein, Britt, Borghi, Claudio, Browning, Colette J, Czesnikiewicz-Guzik, Marta, Lee, Hae-Young, Itoh, Hiroshi, Miura, Katsuyuki, Brunström, Mattias, Campbell, Norm R C, Akinnibossun, Olutope Arinola, Veerabhadrappa, Praveen, Wainford, Richard D, Kruger, Ruan, Thomas, Shane A, Komori, Takahiro, Ralapanawa, Udaya, Cornelissen, Véronique A, Kapil, Vikas, Li, Yan, Zhang, Yuqing, Jafar, Tazeen H, Khan, Nadia, Williams, Bryan, Stergiou, George, Tomaszewski, Maciej

“…Hypertension, defined as persistently elevated systolic blood pressure (SBP) >140 mmHg and/or diastolic blood pressure (DBP) at least 90 mmHg (International…”
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Acute exercise leads to regulation of telomere-associated genes and microRNA expression in immune cells by Chilton, Warrick L, Marques, Francine Z, West, Jenny, Kannourakis, George, Berzins, Stuart P, O'Brien, Brendan J, Charchar, Fadi J

“…Telomeres are specialized nucleoprotein structures that protect chromosomal ends from degradation. These structures progressively shorten during cellular…”
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Telomere Length Maintenance and Cardio-Metabolic Disease Prevention Through Exercise Training by Denham, Joshua, O’Brien, Brendan J., Charchar, Fadi J.

“…Telomeres are tandem repeat DNA sequences located at distal ends of chromosomes that protect against genomic DNA degradation and chromosomal instability…”
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The Y chromosome: a blueprint for men's health? by Maan, Akhlaq A, Eales, James, Akbarov, Artur, Rowland, Joshua, Xu, Xiaoguang, Jobling, Mark A, Charchar, Fadi J, Tomaszewski, Maciej

“…The Y chromosome has long been considered a 'genetic wasteland' on a trajectory to completely disappear from the human genome. The perception of its…”
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Gene Expression Profiling Reveals Renin mRNA Overexpression in Human Hypertensive Kidneys and a Role for MicroRNAs by Marques, Francine Z, Campain, Anna E, Tomaszewski, Maciej, Zukowska-Szczechowska, Ewa, Yang, Yee Hwa J, Charchar, Fadi J, Morris, Brian J

“…The kidney has long been invoked in the etiology of essential hypertension. This could involve alterations in expression of specific genes and microRNAs…”
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Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome by Charchar, Fadi J, PhD, Bloomer, Lisa DS, MSc, Barnes, Timothy A, PhD, Cowley, Mark J, PhD, Nelson, Christopher P, PhD, Wang, Yanzhong, PhD, Denniff, Matthew, BSc, Debiec, Radoslaw, MD, Christofidou, Paraskevi, MSc, Nankervis, Scott, PhD, Dominiczak, Anna F, MD, Bani-Mustafa, Ahmed, PhD, Balmforth, Anthony J, MD, Hall, Alistair S, MD, Erdmann, Jeanette, PhD, Cambien, Francois, PhD, Deloukas, Panos, PhD, Hengstenberg, Christian, MD, Packard, Chris, MD, Schunkert, Heribert, MD, Ouwehand, Willem H, MD, Ford, Ian, PhD, Goodall, Alison H, PhD, Jobling, Mark A, PhD, Samani, Nilesh J, MD, Tomaszewski, Maciej, Dr

“…Summary Background A sexual dimorphism exists in the incidence and prevalence of coronary artery disease—men are more commonly affected than are age-matched…”
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Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies by Morris, Andrew P., Le, Thu H., Wu, Haojia, Akbarov, Artur, van der Most, Peter J., Hemani, Gibran, Smith, George Davey, Mahajan, Anubha, Gaulton, Kyle J., Nadkarni, Girish N., Valladares-Salgado, Adan, Wacher-Rodarte, Niels, Mychaleckyj, Josyf C., Dueker, Nicole D., Guo, Xiuqing, Hai, Yang, Haessler, Jeffrey, Kamatani, Yoichiro, Stilp, Adrienne M., Zhu, Gu, Cook, James P., Ärnlöv, Johan, Blanton, Susan H., de Borst, Martin H., Bottinger, Erwin P., Buchanan, Thomas A., Cechova, Sylvia, Charchar, Fadi J., Chu, Pei-Lun, Damman, Jeffrey, Eales, James, Gharavi, Ali G., Giedraitis, Vilmantas, Heath, Andrew C., Ipp, Eli, Kiryluk, Krzysztof, Kramer, Holly J., Kubo, Michiaki, Larsson, Anders, Lindgren, Cecilia M., Lu, Yingchang, Madden, Pamela A. F., Montgomery, Grant W., Papanicolaou, George J., Raffel, Leslie J., Sacco, Ralph L., Sanchez, Elena, Stark, Holger, Sundstrom, Johan, Taylor, Kent D., Xiang, Anny H., Zivkovic, Aleksandra, Lind, Lars, Ingelsson, Erik, Martin, Nicholas G., Whitfield, John B., Cai, Jianwen, Laurie, Cathy C., Okada, Yukinori, Matsuda, Koichi, Kooperberg, Charles, Chen, Yii-Der Ida, Rundek, Tatjana, Rich, Stephen S., Loos, Ruth J. F., Parra, Esteban J., Cruz, Miguel, Rotter, Jerome I., Snieder, Harold, Tomaszewski, Maciej, Humphreys, Benjamin D., Franceschini, Nora

“…Chronic kidney disease (CKD) affects ~10% of the global population, with considerable ethnic differences in prevalence and aetiology. We assemble genome-wide…”
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Dietary fatty acids and mortality risk from heart disease in US adults: an analysis based on NHANES by Wang, Yutang, Fang, Yan, Witting, Paul K., Charchar, Fadi J., Sobey, Christopher G., Drummond, Grant R., Golledge, Jonathan

“…We investigated the association of dietary intake of major types of fatty acids with heart disease mortality in a general adult cohort with or without a prior…”
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Longer leukocyte telomeres are associated with ultra-endurance exercise independent of cardiovascular risk factors by Denham, Joshua, Nelson, Christopher P, O'Brien, Brendan J, Nankervis, Scott A, Denniff, Matthew, Harvey, Jack T, Marques, Francine Z, Codd, Veryan, Zukowska-Szczechowska, Ewa, Samani, Nilesh J, Tomaszewski, Maciej, Charchar, Fadi J

“…Telomere length is recognized as a marker of biological age, and shorter mean leukocyte telomere length is associated with increased risk of cardiovascular…”
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SLC2A9 is a high-capacity urate transporter in humans by Caulfield, Mark J, Munroe, Patricia B, O'Neill, Deb, Witkowska, Kate, Charchar, Fadi J, Doblado, Manuel, Evans, Sarah, Eyheramendy, Susana, Onipinla, Abiodun, Howard, Philip, Shaw-Hawkins, Sue, Dobson, Richard J, Wallace, Chris, Newhouse, Stephen J, Brown, Morris, Connell, John M, Dominiczak, Anna, Farrall, Martin, Lathrop, G Mark, Samani, Nilesh J, Kumari, Meena, Marmot, Michael, Brunner, Eric, Chambers, John, Elliott, Paul, Kooner, Jaspal, Laan, Maris, Org, Elin, Veldre, Gudrun, Viigimaa, Margus, Cappuccio, Francesco P, Ji, Chen, Iacone, Roberto, Strazzullo, Pasquale, Moley, Kelle H, Cheeseman, Chris

“…Serum uric acid levels in humans are influenced by diet, cellular breakdown, and renal elimination, and correlate with blood pressure, metabolic syndrome,…”
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Telomeres, Aging and Exercise: Guilty by Association? by Chilton, Warrick, O'Brien, Brendan, Charchar, Fadi

“…Telomeres are repetitive tandem DNA sequences that cap chromosomal ends protecting genomic DNA from enzymatic degradation. Telomeres progressively shorten with…”
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Changes in the leukocyte methylome and its effect on cardiovascular-related genes after exercise by Denham, Joshua, O'Brien, Brendan J, Marques, Francine Z, Charchar, Fadi J

“…Physical exercise has proven cardiovascular benefits, yet there is no clear understanding of the related molecular mechanisms leading to this. Here we…”
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Increased expression of telomere-regulating genes in endurance athletes with long leukocyte telomeres by Denham, Joshua, O'Brien, Brendan J, Prestes, Priscilla R, Brown, Nicholas J, Charchar, Fadi J

“…Leukocyte telomeres shorten with age, and excessive shortening is associated with age-related cardiometabolic diseases. Exercise training may prevent disease…”
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Fasting triglycerides are positively associated with cardiovascular mortality risk in people with diabetes by Wang, Yutang, Fang, Yan, Magliano, Dianna J, Charchar, Fadi J, Sobey, Christopher G, Drummond, Grant R, Golledge, Jonathan

“…Abstract Aims We investigated the association of fasting triglycerides with cardiovascular disease (CVD) mortality. Methods and results This cohort study…”
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A Guide to the Short, Long and Circular RNAs in Hypertension and Cardiovascular Disease by Prestes, Priscilla R, Maier, Michelle C, Woods, Bradley A, Charchar, Fadi J

“…Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in adults in developed countries. CVD encompasses many diseased states, including…”
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