Search Results - "Charbit, Hanna"

Investigating Expression Dynamics of miR-21 and miR-10b in Glioblastoma Cells In Vitro: Insights into Responses to Hypoxia and Secretion Mechanisms by Charbit, Hanna, Lavon, Iris

“…Glioblastoma poses significant challenges in oncology, with bevacizumab showing promise as an antiangiogenic treatment but with limited efficacy. microRNAs…”
Get full text

Intracranial Assessment of Androgen Receptor Antagonists in Mice Bearing Human Glioblastoma Implants by Zalcman, Nomi, Larush, Liraz, Ovadia, Haim, Charbit, Hanna, Magdassi, Shlomo, Lavon, Iris

“…The median survival time of patients with an aggressive brain tumor, glioblastoma, is still poor due to ineffective treatment. The discovery of androgen…”
Get full text

Blood Levels of Co-inhibitory-Receptors: A Biomarker of Disease Prognosis in Multiple Sclerosis by Lavon, Iris, Heli, Coral, Brill, Livnat, Charbit, Hanna, Vaknin-Dembinsky, Adi

“…The clinical course of multiple sclerosis ranges from benign with little disease progression and minimal disability, to severe disease requiring intensive…”
Get full text

ANGI-09. CIRCULATING MIR-10B AND MIR-21 IN PATIENTS WITH GBM TREATED WITH BEVACIZUMAB ARE SECRETED TO THE CIRCULATION BY PROTEINS AND THEIR HIGH QUANTIFICATION IS PROBABLY THE RESULT OF DRUG-INDUCED TUMOR HYPOXIA by Charbit, Hanna, Mordechai, Anat, Lossos, Alexander, Lavon, Iris

“…Abstract Bevacizumab is a one of the salvage therapy to patients with recurrent GBM. Antiangiogenic treatment such bevacizumab reduce blood supply and…”
Get full text

Dynamics of circulating hypoxia-mediated miRNAs and tumor response in patients with high-grade glioma treated with bevacizumab by Siegal, Tali, Charbit, Hanna, Paldor, Iddo, Zelikovitch, Bracha, Canello, Tamar, Benis, Arriel, Wong, Michael L, Morokoff, Andrew P, Kaye, Andrew H, Lavon, Iris

“…OBJECTIVE Bevacizumab is an antiangiogenic agent under investigation for use in patients with high-grade glioma. It produces a high rate of radiological…”
Get full text

Androgen receptor: a potential therapeutic target for glioblastoma by Zalcman, Nomi, Canello, Tamar, Ovadia, Haim, Charbit, Hanna, Zelikovitch, Bracha, Mordechai, Anat, Fellig, Yakov, Rabani, Stav, Shahar, Tal, Lossos, Alexander, Lavon, Iris

“…The median survival time of patients with glioblastoma is still poor (14.6 month), partly due to a lack of effective treatment. We have observed that androgen…”
Get full text

NIMG-30. PET IMAGING OF ANDROGEN RECEPTOR EXPRESSION IN PATIENTS WITH GBM USING [18F]-FDHT by Mordechai, Anat, Shamni, Ofer, Zalcman, Nomi, Moscovici, Samuel, Chicheportiche, Alexandre, Shoshan, Yigal, Shahar, Tal, Charbit, Hanna, Guterman, Mijal, Paldor, Iddo, Mishani, Eyal, Lossos, Alexander, Orevi, Marina, Lavon, Iris

Get full text

Expression level of miRNAs on chromosome 14q32.31 region correlates with tumor aggressiveness and survival of glioblastoma patients by Shahar, Tal, Granit, Avital, Zrihan, Daniel, Canello, Tamar, Charbit, Hanna, Einstein, Ofira, Rozovski, Uri, Elgavish, Sharona, Ram, Zvi, Siegal, Tali, Lavon, Iris

“…The 54 microRNAs (miRNAs) within the DLK-DIO3 genomic region on chromosome 14q32.31 (cluster-14-miRNAs) are organized into sub-clusters 14A and 14B. These…”
Get full text

Rapid Classification of Sarcomas Using Methylation Fingerprint: A Pilot Study by Iluz, Aviel, Maoz, Myriam, Lavi, Nir, Charbit, Hanna, Or, Omer, Olshinka, Noam, Demma, Jonathan Abraham, Adileh, Mohammad, Wygoda, Marc, Blumenfeld, Philip, Gliner-Ron, Masha, Azraq, Yusef, Moss, Joshua, Peretz, Tamar, Eden, Amir, Zick, Aviad, Lavon, Iris

“…Sarcoma classification is challenging and can lead to treatment delays. Previous studies used DNA aberrations and machine-learning classifiers based on…”
Get full text

Circulating microRNAs as biomarkers for rituximab therapy, in neuromyelitis optica (NMO) by Vaknin-Dembinsky, Adi, Charbit, Hanna, Brill, Livnat, Abramsky, Oded, Gur-Wahnon, Devorah, Ben-Dov, Iddo Z, Lavon, Iris

“…Neuromyelitis optica (NMO) is a chronic autoimmune disease of the central nervous system (CNS). The main immunological feature of the disease is the presence…”
Get full text

QKI-V5 is downregulated in CNS inflammatory demyelinating diseases by Lavon, Iris, leykin, Ina, Charbit, Hanna, Binyamin, Orli, Brill, Livnat, Ovadia, Haim, Vaknin-Dembinsky, Adi

“…•QKI gene encodes a RNA-binding-protein that plays a central role in myelination.•Expression of QKI-V5 is decreased in the blood of NMO and MS patients.•Sera…”
Get full text

[18F]-FDHT PET/CT as a tool for imaging androgen receptor expression in high-grade glioma by Orevi, Marina, Shamni, Ofer, Zalcman, Nomi, Chicheportiche, Alexandre, Mordechai, Anat, Moscovici, Samuel, Shoshan, Yigal, Shahar, Tal, Charbit, Hanna, Gutreiman, Mijal, Paldor, Iddo, Mishani, Eyal, Lossos, Alexander, Lavon, Iris

“…Abstract Background G lioblastoma (GBM) is associated with poor overall survival. Recently, we showed that androgen receptor (AR) protein is overexpressed in…”
Get full text

CSIG-13. ANDROGEN RECEPTOR IS INVOLVED IN GLIOBLASTOMA AND PRESENTS A POTENTIAL THERAPEUTIC TARGET by Lavon, Iris, Zalsman, Nomi, Canello, Tamar, Charbit, Hanna, Zelikovitch, Bracha, Mordechai, Anat, Fellig, Yakov, Rabani, Stav, Shahar, Tal, Lossos, Alexander

Get full text

CSIG-24. ANDROGEN RECEPTOR IS A POTENTIAL THERAPEUTIC TARGET IN GLIOBLASTOMA by Zalsman, Nomi, Canello, Tamar, Ovadia, Haim, Charbit, Hanna, Zelikovitch, Bracha, Mordechai, Anat, Fellig, Yakov, Rabani, Stav, Shahar, Tal, Lossos, Alexander, Lavon, Iris

“…Androgen receptor (AR) gene is mapped to Xq11-12. It functions as a steroid-hormone-activated-transcription-factor. AR splice variants lacking the…”
Get full text

Sex-specific prediction of interferon beta therapy response in relapsing-remitting multiple sclerosis by Charbit, Hanna, Benis, Arriel, Geyshis, Bella, Karussis, Dimitrios, Petrou, Panayota, Vaknin-Dembinsky, Adi, Lavon, Iris

“…Abstract Multiple sclerosis (MS) is a demyelinating disorder predominantly affecting young people. Currently, interferon beta (IFNβ) is a common treatment for…”
Get full text

CBM-15DYNAMICS OF CIRCULATING HYPOXIA MEDIATED miRNAs AND TUMOR RESPONSE IN HIGH-GRADE GLIOMA PATIENTS TREATED WITH BEVACIZUMAB by Siegal, Tali, Charbit, Hanna, Paldor, Iddo, Zelikovitch, Bracha, Canello, Tamar, Mordechai, Anat, Benis, Arriel, Wong, Michael L., Morokoff, Andrew P., Kaye, Andrew H., Lavon, Iris

Get full text

GENT-03. EXPRESSION LEVEL OF miRNAs ON CHROMOSOME 14q32.31 REGION CORRELATES WITH TUMOR AGGRESSIVENESS AND SURVIVAL OF GLIOBLASTOMA PATIENTS by Shahar, Tal, Granit, Avital, Zrihan, Daniel, Canello, Tamar, Charbit, Hanna, Einstein, Ofira, Rozovski, Uri, Elgavish, Sharona, Ram, Zvi, Siegal, Tali, Lavon, Iris

Get full text