Search Results - "Chapuis, Catherine"

Induction of oxidative stress, lysosome activation and autophagy by nanoparticles in human brain-derived endothelial cells by Halamoda Kenzaoui, Blanka, Chapuis Bernasconi, Catherine, Guney-Ayra, Seher, Juillerat-Jeanneret, Lucienne

“…Different types of NPs (nanoparticles) are currently under development for diagnostic and therapeutic applications in the biomedical field, yet our knowledge…”
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CHD3 and CHD4 recruitment and chromatin remodeling activity at DNA breaks is promoted by early poly(ADP-ribose)-dependent chromatin relaxation by Smith, Rebecca, Sellou, Hafida, Chapuis, Catherine, Huet, Sébastien, Timinszky, Gyula

“…Abstract One of the first events to occur upon DNA damage is the local opening of the compact chromatin architecture, facilitating access of repair proteins to…”
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The poly(ADP-ribose)-dependent chromatin remodeler Alc1 induces local chromatin relaxation upon DNA damage by Sellou, Hafida, Lebeaupin, Théo, Chapuis, Catherine, Smith, Rebecca, Hegele, Anna, Singh, Hari R, Kozlowski, Marek, Bultmann, Sebastian, Ladurner, Andreas G, Timinszky, Gyula, Huet, Sébastien

“…Chromatin relaxation is one of the earliest cellular responses to DNA damage. However, what determines these structural changes, including their ATP…”
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The chromatin remodeler ALC1 underlies resistance to PARP inhibitor treatment by Juhász, Szilvia, Smith, Rebecca, Schauer, Tamás, Spekhardt, Dóra, Mamar, Hasan, Zentout, Siham, Chapuis, Catherine, Huet, Sébastien, Timinszky, Gyula

“…Poly(ADP-ribose) polymerase (PARP) inhibitors are used in the treatment of BRCA-deficient cancers, with treatments currently extending toward other homologous…”
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Analysis of DNA Replication by Optical Mapping in Nanochannels by Lacroix, Joris, Pélofy, Sandrine, Blatché, Charline, Pillaire, Marie-Jeanne, Huet, Sébastien, Chapuis, Catherine, Hoffmann, Jean-Sébastien, Bancaud, Aurélien

“…DNA replication is essential to maintain genome integrity in S phase of the cell division cycle. Accumulation of stalled replication forks is a major source of…”
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Myosin Va Mediates Docking of Secretory Granules at the Plasma Membrane by Desnos, Claire, Huet, Sebastien, Fanget, Isabelle, Chapuis, Catherine, Bottiger, Caroline, Racine, Victor, Sibarita, Jean-Baptiste, Henry, Jean-Pierre, Darchen, Francois

“…Myosin Va (MyoVa) is a prime candidate for controlling actin-based organelle motion in neurons and neuroendocrine cells. Its function in secretory granule (SG)…”
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Differential stress reaction of human colon cells to oleic-acid-stabilized and unstabilized ultrasmall iron oxide nanoparticles by Schütz, Catherine A, Staedler, Davide, Crosbie-Staunton, Kieran, Movia, Dania, Chapuis Bernasconi, Catherine, Kenzaoui, Blanka Halamoda, Prina-Mello, Adriele, Juillerat-Jeanneret, Lucienne

“…Therapeutic engineered nanoparticles (NPs), including ultrasmall superparamagnetic iron oxide (USPIO) NPs, may accumulate in the lower digestive tract…”
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Angiotensin II type 2 receptor-mediated vasodilation in human coronary microarteries by BATENBURG, Wendy W, GARRELDS, Ingrid M, BERNASCONI, Catherine Chapuis, JUILLERAT-JEANNERET, Lucienne, VAN KATS, Jorge P, SAXENA, Pramod R, DANSER, A. H

“…Angiotensin (Ang) II type 2 (AT2) receptor stimulation results in coronary vasodilation in the rat heart. In contrast, AT2 receptor-mediated vasodilation could…”
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Transfer of Ultrasmall Iron Oxide Nanoparticles from Human Brain-Derived Endothelial Cells to Human Glioblastoma Cells by Halamoda Kenzaoui, Blanka, Angeloni, Silvia, Overstolz, Thomas, Niedermann, Philippe, Chapuis Bernasconi, Catherine, Liley, Martha, Juillerat-Jeanneret, Lucienne

“…Nanoparticles (NPs) are being used or explored for the development of biomedical applications in diagnosis and therapy, including imaging and drug delivery…”
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Stress reaction of kidney epithelial cells to inorganic solid-core nanoparticles by Halamoda Kenzaoui, Blanka, Chapuis Bernasconi, Catherine, Juillerat-Jeanneret, Lucienne

“…A route of accumulation and elimination of therapeutic engineered nanoparticles (NPs) may be the kidney. Therefore, the interactions of different solid-core…”
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HPF1-dependent histone ADP-ribosylation triggers chromatin relaxation to promote the recruitment of repair factors at sites of DNA damage by Smith, Rebecca, Zentout, Siham, Rother, Magdalena, Bigot, Nicolas, Chapuis, Catherine, Mihuț, Alexandra, Zobel, Florian Franz, Ahel, Ivan, van Attikum, Haico, Timinszky, Gyula, Huet, Sébastien

“…Poly(ADP-ribose) polymerase 1 (PARP1) activity is regulated by its co-factor histone poly(ADP-ribosylation) factor 1 (HPF1). The complex formed by HPF1 and…”
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Histone ADP-ribosylation promotes resistance to PARP inhibitors by facilitating PARP1 release from DNA lesions by Zentout, Siham, Imburchia, Victor, Chapuis, Catherine, Duma, Lena, Schützenhofer, Kira, Prokhorova, Evgeniia, Ahel, Ivan, Smith, Rebecca, Huet, Sébastien

“…Poly(ADP-ribose) polymerase 1 (PARP1) has emerged as a central target for cancer therapies due to the ability of PARP inhibitors to specifically kill tumors…”
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The recruitment of ACF1 and SMARCA5 to DNA lesions relies on ADP-ribosylation dependent chromatin unfolding by Pinto Jurado, Eva, Smith, Rebecca, Bigot, Nicolas, Chapuis, Catherine, Timinszky, Gyula, Huet, Sébastien

“…ADP-ribosylation signaling orchestrates the recruitment of various repair actors and chromatin remodeling processes promoting access to lesions during the…”
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Organometallic Ruthenium Inhibitors of Glutathione-S-Transferase P1-1 as Anticancer Drugs by Ang, Wee Han, De Luca, Anastasia, Chapuis-Bernasconi, Catherine, Juillerat-Jeanneret, Lucienne, Lo Bello, Mario, Dyson, Paul J.

“…Ruthenium–arene complexes conjugated to ethacrynic acid were prepared as part of a strategy to develop novel glutathione‐S‐transferase (GST) inhibitors with…”
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Poly(ADP-ribose)-dependent chromatin unfolding facilitates the association of DNA-binding proteins with DNA at sites of damage by Smith, Rebecca, Lebeaupin, Théo, Juhász, Szilvia, Chapuis, Catherine, D’Augustin, Ostiane, Dutertre, Stéphanie, Burkovics, Peter, Biertümpfel, Christian, Timinszky, Gyula, Huet, Sébastien

“…Abstract The addition of poly(ADP-ribose) (PAR) chains along the chromatin fiber due to PARP1 activity regulates the recruitment of multiple factors to sites…”
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Crowded chromatin is not sufficient for heterochromatin formation and not required for its maintenance by Walter, Andreas, Chapuis, Catherine, Huet, Sébastien, Ellenberg, Jan

“…In contrast to cytoplasmic organelles, which are usually separated from the rest of the cell by phospholipid membranes, nuclear compartments are readily…”
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Multiplexing PKA and ERK1&2 kinases FRET biosensors in living cells using single excitation wavelength dual colour FLIM by Demeautis, Claire, Sipieter, François, Roul, Julien, Chapuis, Catherine, Padilla-Parra, Sergi, Riquet, Franck B., Tramier, Marc

“…Monitoring of different signalling enzymes in a single assay using multiplex biosensing provides a multidimensional workspace to elucidate biological…”
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Dynamic BTB-domain filaments promote clustering of ZBTB proteins by Mance, Lucija, Bigot, Nicolas, Zhamungui Sánchez, Edison, Coste, Franck, Martín-González, Natalia, Zentout, Siham, Biliškov, Marin, Pukało, Zofia, Mishra, Aanchal, Chapuis, Catherine, Arteni, Ana-Andreea, Lateur, Axelle, Goffinont, Stéphane, Gaudon, Virginie, Talhaoui, Ibtissam, Casuso, Ignacio, Beaufour, Martine, Garnier, Norbert, Artzner, Franck, Cadene, Martine, Huet, Sébastien, Castaing, Bertrand, Suskiewicz, Marcin Józef

“…The formation of dynamic protein filaments contributes to various biological functions by clustering individual molecules together and enhancing their binding…”
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Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes by Ellenberg, Jan, Neumann, Beate, Walter, Thomas, Hériché, Jean-Karim, Bulkescher, Jutta, Erfle, Holger, Conrad, Christian, Rogers, Phill, Poser, Ina, Held, Michael, Liebel, Urban, Cetin, Cihan, Sieckmann, Frank, Pau, Gregoire, Kabbe, Rolf, Wünsche, Annelie, Satagopam, Venkata, Schmitz, Michael H. A, Chapuis, Catherine, Gerlich, Daniel W, Schneider, Reinhard, Eils, Roland, Huber, Wolfgang, Peters, Jan-Michael, Hyman, Anthony A, Durbin, Richard, Pepperkok, Rainer

“…Despite our rapidly growing knowledge about the human genome, we do not know all of the genes required for some of the most basic functions of life. To start…”
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Identification of key residues of the DNA glycosylase OGG1 controlling efficient DNA sampling and recruitment to oxidized bases in living cells by D’Augustin, Ostiane, Gaudon, Virginie, Siberchicot, Capucine, Smith, Rebecca, Chapuis, Catherine, Depagne, Jordane, Veaute, Xavier, Busso, Didier, Di Guilmi, Anne-Marie, Castaing, Bertrand, Radicella, J Pablo, Campalans, Anna, Huet, Sébastien

“…Abstract The DNA-glycosylase OGG1 oversees the detection and clearance of the 7,8-dihydro-8-oxoguanine (8-oxoG), which is the most frequent form of oxidized…”
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