Search Results - "Chappuis, P"

Dermoscopy, a useful tool for general practitioners in melanoma screening: a nationwide survey by Chappuis, P., Duru, G., Marchal, O., Girier, P., Dalle, S., Thomas, L.

“…Summary Background Dermoscopy improves diagnostic accuracy in melanoma, as shown by several meta‐analyses. Although it is used by general practitioners (GPs)…”
Get full text

Right colon cancer: left behind by Gervaz, P, Usel, M, Rapiti, E, Chappuis, P, Neyroud-Kaspar, I, Bouchardy, C

“…Abstract Introduction Prognosis of colon cancer (CC) has steadily improved during the past three decades. This trend, however, may vary according to proximal…”
Get full text

Design and manufacturing of bulk tungsten tiles for WEST outer limiter by Firdaouss, M., Chappuis, P., Gazzotti, S., Lipa, M., Portafaix, C., Diez, M.

“…•WEST outer start-up limiter was equipped with CFC tiles coated with tungsten.•.Experimental campaigns demonstrate that coating is fragile regarding very…”
Get full text

Strontium ranelate inhibits bone resorption while maintaining bone formation in alveolar bone in monkeys ( Macaca fascicularis) by Buehler, J, Chappuis, P, Saffar, J.L, Tsouderos, Y, Vignery, A

“…Strontium ranelate (S12911) has previously been shown to stimulate bone formation and inhibit bone resorption in rats. To determine whether strontium ranelate…”
Get full text

A significant response to neoadjuvant chemotherapy in BRCA1/2 related breast cancer by Chappuis, P O, Goffin, J, Wong, N, Perret, C, Ghadirian, P, Tonin, P N, Foulkes, W D

Get full text

ITER plasma-facing components by Merola, Mario, Loesser, D., Martin, A., Chappuis, P., Mitteau, R., Komarov, V., Pitts, R.A., Gicquel, S., Barabash, V., Giancarli, L., Palmer, J., Nakahira, M., Loarte, A., Campbell, D., Eaton, R., Kukushkin, A., Sugihara, M., Zhang, F., Kim, C.S., Raffray, R., Ferrand, L., Yao, D., Sadakov, S., Furmanek, A., Rozov, V., Hirai, T., Escourbiac, F., Jokinen, T., Calcagno, B., Mori, S.

“…The ITER plasma-facing components directly face the thermonuclear plasma and include the divertor, the blanket and the test blanket modules with their…”
Get full text

BRCA1/BRCA2 germline mutations and chemotherapy-related hematological toxicity in breast cancer patients by Friedlaender, A., Vuillemier, A., Viassolo, V., Ayme, A., De Talhouet, S., Combes, J.-D., Peron, J., Bodmer, A., Giraud, S., Buisson, A., Bonadona, V., Gauchat-Bouchardy, I., Tredan, O., Chappuis, P., Labidi-Galy, S.I.

Get full text

The design of the ITER first wall panels by Mitteau, R., Calcagno, B., Chappuis, P., Eaton, R., Gicquel, S., Chen, J., Labusov, A., Martin, A., Merola, M., Raffray, R., Ulrickson, M., Zacchia, F.

“…•The ITER blanket is in the final stage of design completion.•Issues raised about the blanket heat loads and remote handling strategy are addressed, while…”
Get full text

Recent increase of breast cancer incidence among women under the age of forty by BOUCHARDY, C, FIORETTA, G, CHAPPUIS, P, SAPPINO, A.-P, RAPITI, E, VERKOOIJEN, H. M, VLASTOS, G, SCHAEFER, P, DELALOYE, J.-F, NEYROUD-CASPAR, I, BALMER MAJNO, S, WESPI, Y, FORNI, M

“…Using data from the Geneva Cancer Registry, we found that in 2002-2004, breast cancer incidence in women aged 25-39 years increased by 46.7% per year (95% CI:…”
Get full text

ITER blanket manifold final design and validation by Edwards, P., Calcagno, B., Chappuis, P., Chaullier, C., Choi, C.-H., Dellopoulos, G., Gicquel, S., Martin, A., Mori, S., Norman, M., Raffray, R.

“…•The Blanket Manifolds provide cooling water to the plasma facing Blanket.•The design, verification by analysis and practical validation have been…”
Get full text

Corpus callosum abnormalities in Wilson's disease by Trocello, J M, Guichard, J P, Leyendecker, A, Pernon, M, Chaine, P, El Balkhi, S, Poupon, J, Chappuis, P, Woimant, F

“…IntroductionWilson's disease (WD) with neurological presentation is associated with brain lesions classically localised in globus pallidus, putamen, thalamus,…”
Get full text

Cyclin E expression in breast cancer: predicting germline BRCA1 mutations, prognosis and response to treatment by Chappuis, P. O., Donato, E., Goffin, J. R., Wong, N., Bégin, L. R., Kapusta, L. R., Brunet, J.-S., Porter, P., Foulkes, W. D.

“…Background:: Elevated levels of the cell cycle protein cyclin E, and low levels of its inhibitor, p27Kip1, have been associated with a poor prognosis following…”
Get full text

Impact of a positive family history on diagnosis, management, and survival of breast cancer: different effects across socio-economic groups by Verkooijen, H. M, Rapiti, E, Fioretta, G, Vinh-Hung, V, Keller, J, Benhamou, S, Vlastos, G, Chappuis, P. O, Bouchardy, C

“…Background This study aims to investigate whether increased awareness of breast cancer, due to a positive family history (FH), reduces diagnostic, therapeutic,…”
Get full text

Impact of familial risk factors on management and survival of early-onset breast cancer: a population-based study by VERKOOIJEN, H. M, CHAPPUIS, P. O, RAPITI, E, VLASTOS, G, FIORETTA, G, SARP, S, SAPPINO, A. P, SCHUBERT, H, BOUCHARDY, C

“…This population-based study evaluates the impact of a strong family history of breast cancer on management and survival of women with early-onset disease. We…”
Get full text

Hormonal therapy for oestrogen receptor-negative breast cancer is associated with higher disease-specific mortality by Merglen, A., Verkooijen, H.M., Fioretta, G., Neyroud-Caspar, I., Vinh-Hung, V., Vlastos, G., Chappuis, P.O., Castiglione, M., Rapiti, E., Bouchardy, C.

“…Tamoxifen has a remarkable impact on the outcome of oestrogen receptor (ER)-positive breast cancer. Without proven benefits, tamoxifen is occasionally…”
Get full text

Germline BRCA1/2 mutations and p27(Kip1) protein levels independently predict outcome after breast cancer by Chappuis, P O, Kapusta, L, Bégin, L R, Wong, N, Brunet, J S, Narod, S A, Slingerland, J, Foulkes, W D

“…Decreased levels of the cyclin-dependent kinase inhibitor p27(Kip1) in breast cancer are associated with a poor outcome. The prognostic significance of BRCA1/2…”
Get full text

A Simple p53 Functional Assay for Screening Cell Lines, Blood, and Tumors by J. -M. Flaman, Frebourg, T., Moreau, V., Charbonnier, F., Martin, C., Chappuis, P., A. -P. Sappino, J. -M. Limacher, Bron, L., Benhattar, J., Tada, M., Van Meir, E. G., Estreicher, A., Iggo, R. D.

“…Mutations in the p53 gene are implicated in the pathogenesis of half of all human tumors. We have developed a simple functional assay for p53 mutation in which…”
Get full text

Significant contribution of germline BRCA2 rearrangements in male breast cancer families by TOURNIER, Isabelle, BRESSAC-DE PAILLERETS, Brigitte, LORTHOLARY, Alain, CHAPPUIS, Pierre, BOURDON, Violaine, BONADONA, Valérie, MAUGARD, Christine, GILBERT, Brigitte, NOGUES, Catherine, FREBOURG, Thierry, TOSI, Mario, SOBOL, Hagay, STOPPA-LYONNET, Dominique, LIDEREAU, Rosette, BARROIS, Michel, MAZOYER, Sylvie, COULET, Florence, HARDOUIN, Agnès, CHOMPRET, Agnès

“…Although screening for large deletions or duplications of the BRCA1 gene is becoming a routine component of the molecular diagnosis of familial breast cancer,…”
Get full text

Design finalization and material qualification towards procurement of the ITER vacuum vessel by Ioki, K., Barabash, V., Bachmann, C., Chappuis, P., Choi, C.H., Cordier, J-J., Giraud, B., Gribov, Y., Heitzenroeder, Ph, Her, N., Johnson, G., Jones, L., Jun, C., Kim, B.C., Kuzmin, E., Loesser, D., Martin, A., Merola, M., Pathak, H., Readman, P., Sugihara, M., Terasawa, A., Utin, Yu, Wang, X., Wu, S., Yu, J.

“…Procurement arrangements for ITER key components including the vacuum vessel (VV) have been signed and the ITER activities are now fully devoted towards…”
Get full text

The influence of familial and hereditary factors on the prognosis of breast cancer by Chappuis, P. O., Rosenblatt, J., Foulkes, W. D.

“…Background: Family history is a well recognized risk factor for breast cancer, but its impact in terms of breast cancer survival is uncertain. The recent…”
Get full text