Search Results - "Chappell, Ben. G. N."
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A general catalytic β-C-H carbonylation of aliphatic amines to β-lactams
Published in Science (American Association for the Advancement of Science) (18-11-2016)“…Methods for the synthesis and functionalization of amines are intrinsically important to a variety of chemical applications. We present a general…”
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Selective Reductive Elimination at Alkyl Palladium(IV) by Dissociative Ligand Ionization: Catalytic C(sp3)−H Amination to Azetidines
Published in Angewandte Chemie International Edition (12-03-2018)“…A palladium(II)‐catalyzed γ‐C−H amination of cyclic alkyl amines to deliver highly substituted azetidines is reported. The use of a benziodoxole tosylate…”
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3
Mechanistic investigation into the C(sp 3 )-H acetoxylation of morpholinones
Published in Chemical science (Cambridge) (07-01-2019)“…The study of a selective palladium(ii)-catalyzed C(sp )-H acetoxylation reaction on a class of cyclic alkyl amines is reported. Computational modelling and…”
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4
Selective Reductive Elimination at Alkyl Palladium(IV) by Dissociative Ligand Ionization: Catalytic C(sp3)−H Amination to Azetidines
Published in Angewandte Chemie (12-03-2018)“…A palladium(II)‐catalyzed γ‐C−H amination of cyclic alkyl amines to deliver highly substituted azetidines is reported. The use of a benziodoxole tosylate…”
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5
Mechanistic investigation into the C(sp3)-H acetoxylation of morpholinonesElectronic supplementary information (ESI) available: Experimental procedures, characterization data and kinetic details. See DOI: 10.1039/c8sc03434f
Published 19-12-2018“…The study of a selective palladium( ii )-catalyzed C(sp 3 )-H acetoxylation reaction on a class of cyclic alkyl amines is reported. Computational modelling and…”
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Mechanistic investigation into the C(sp3)–H acetoxylation of morpholinones† †Electronic supplementary information (ESI) available: Experimental procedures, characterization data and kinetic details. See DOI: 10.1039/c8sc03434f
Published in Chemical science (Cambridge) (01-10-2018)“…The study of a selective palladium( ii )-catalyzed C(sp 3 )–H acetoxylation reaction on a class of cyclic alkyl amines is reported. The study of a selective…”
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7
A general catalytic [beta]-C-H carbonylation of aliphatic amines to [beta]-lactams
Published in Science (American Association for the Advancement of Science) (18-11-2016)“…Strained β-lactam rings are a key feature of penicillin and some other drugs. Willcox et al. designed a versatile route to these four-membered ring motifs…”
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