Search Results - "Chapoval, Andrei I"

Peptide Blocking CTLA-4 and B7-1 Interaction by Podlesnykh, Stepan V, Abramova, Kristina E, Gordeeva, Anastasia, Khlebnikov, Andrei I, Chapoval, Andrei I

“…Discovery of the B7 family immune checkpoints such as CTLA-4 (CD152), PD-1 (CD279), as well as their ligands B7-1 (CD80), B7-2 (CD86), B7-H1 (PD-L1, CD274),…”
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Can Modern Molecular Modeling Methods Help Find the Area of Potential Vulnerability of Flaviviruses? by Shanshin, Daniil V., Borisevich, Sophia S., Bondar, Alexander A., Porozov, Yuri B., Rukhlova, Elena A., Protopopova, Elena V., Ushkalenko, Nikita D., Loktev, Valery B., Chapoval, Andrei I., Ilyichev, Alexander A., Shcherbakov, Dmitriy N.

“…Flaviviruses are single-stranded RNA viruses that have emerged in recent decades and infect up to 400 million people annually, causing a variety of potentially…”
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Isopentenyl Pyrophosphate–Activated CD56+ γδ T Lymphocytes Display Potent Antitumor Activity toward Human Squamous Cell Carcinoma by ALEXANDER, Alan A. Z, MANIAR, Amudhan, CUMMINGS, Jean-Saville, HEBBELER, Andrew M, SCHUIZE, Dan H, GASTMAN, Brian R, PAUZA, C. David, STROME, Scott E, CHAPOVAL, Andrei I

“…Purpose: The expression of CD56, a natural killer cell–associated molecule, on αβ T lymphocytes correlates with their increased antitumor effector function…”
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Multiple treatment interruptions and protecting HIV-specific CD4 T cells enable durable CD8 T cell response and viral control by Jain, Anshika, Canepa, Gaspar E, Liou, Mei-Ling, Fledderman, Emily L, Chapoval, Andrei I, Xiao, Lingzhi, Mukherjee, Ipsita, Balogun, Bushirat M, Huaman-Vergara, Hellen, Galvin, Jeffrey A, Kumar, Princy N, Bordon, José, Conant, Marcus A, Boyle, Jefferey S

“…Human Immunodeficiency Virus (HIV) remains a global health challenge, and novel approaches to improve HIV control are significantly important. The cell and…”
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Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors by Wilcox, Ryan A, Flies, Dallas B, Zhu, Gefeng, Johnson, Aaron J, Tamada, Koji, Chapoval, Andrei I, Strome, Scott E, Pease, Larry R, Chen, Lieping

“…Treatment of advanced, poorly immunogenic tumors in animal models, considered the closest simulation available thus far for conditions observed in cancer…”
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CD137 Promotes Proliferation and Survival of Human B Cells by Zhang, Xiaoyu, Voskens, Caroline J, Sallin, Michelle, Maniar, Amudhan, Montes, Carolina L, Zhang, Yue, Lin, Wei, Li, Guoyan, Burch, Erin, Tan, Ming, Hertzano, Ronna, Chapoval, Andrei I, Tamada, Koji, Gastman, Brian R, Schulze, Dan H, Strome, Scott E

“…CD137 (4-1BB)-mediated costimulation plays an important role in directing the fate of Ag-stimulated T cells and NK cells, yet the role of CD137 in mediating B…”
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Cutting Edge: Expression of Functional CD137 Receptor by Dendritic Cells by Wilcox, Ryan A, Chapoval, Andrei I, Gorski, Kevin S, Otsuji, Mizuto, Shin, Tahiro, Flies, Dallas B, Tamada, Koji, Mittler, Robert S, Tsuchiya, Haruo, Pardoll, Drew M, Chen, Lieping

“…Interaction between dendritic cells (DCs) and T cells is a prerequisite for the initiation of a T cell response. The molecular nature of this interaction…”
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Mapping Solvent Entrapment in Multiphase Systems by Electrogenerated Chemiluminescence by Glasscott, Matthew W, Voci, Silvia, Kauffmann, Philip J, Chapoval, Andrei I, Dick, Jeffrey E

“…The interfacial properties of multiphase systems are often difficult to quantify. We describe the observation and quantification of immiscible solvent…”
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Semaphorins 4A and 4D in chronic inflammatory diseases by Chapoval, Svetlana P., Vadasz, Zahava, Chapoval, Andrei I., Toubi, Elias

“…Long-term inflammatory processes directed at a particular endogenous or exogenous antigen, or sometimes of unknown etiology, form the pathogenetic basis for…”
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Recent advances in potentiometric biosensing by Walker, Nicole L., Roshkolaeva, Anastasiya B., Chapoval, Andrei I., Dick, Jeffrey E.

“…Potentiometric biosensors are incredibly versatile tools with budding uses in industry, security, environmental safety, and human health. This mini-review on…”
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Immunosignature: Serum Antibody Profiling for Cancer Diagnostics by Chapoval, Andrei I, Legutki, J Bart, Stafford, Philip, Trebukhov, Andrey V, Johnston, Stephen A, Shoikhet, Yakov N, Lazarev, Alexander F

“…Biomarkers for preclinical diagnosis of cancer are valuable tools for detection of malignant tumors at early stages in groups at risk and screening healthy…”
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B7-H4, a Molecule of the B7 Family, Negatively Regulates T Cell Immunity by Sica, Gabriel L, Choi, In-Hak, Zhu, Gefeng, Tamada, Koji, Wang, Sheng-Dian, Tamura, Hideto, Chapoval, Andrei I, Flies, Dallas B, Bajorath, Jürgen, Chen, Lieping

“…We identify a B7 family molecule, B7-H4, by protein sequence analysis and comparative molecular modeling. While B7-H4 mRNA is widely distributed in mouse and…”
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Tumor-Induced Senescent T Cells with Suppressor Function : A Potential Form of Tumor Immune Evasion by MONTES, Carolina L, CHAPOVAL, Andrei I, NELSON, Jonas, ORHUE, Vbenosa, XIAOYU ZHANG, SCHULZE, Dan H, STROME, Scott E, GASTMAN, Brian R

“…Senescent and suppressor T cells are reported to be increased in select patients with cancer and are poor prognostic indicators. Based on the association of…”
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B7-H3: A costimulatory molecule for T cell activation and IFN-γ production by Chen, Lieping, Chapoval, Andrei I, Ni, Jian, Lau, Julie S, Wilcox, Ryan A, Flies, Dallas B, Liu, Ding, Dong, Haidong, Sica, Gabriel L, Zhu, Gefeng, Tamada, Koji

“…We describe here a newly identified member of the human B7 family, designated B7 homolog 3 (B7-H3), that shares 20-27% amino acid identity with other B7 family…”
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BTNL8, a butyrophilin-like molecule that costimulates the primary immune response by Chapoval, Andrei I., Smithson, Glennda, Brunick, Linda, Mesri, Mehdi, Boldog, Ferenc L., Andrew, David, Khramtsov, Nikolai V., Feshchenko, Elena A., Starling, Gary C., Mezes, Peter S.

“…•The manuscript describes a new function for BTNL8 (butyrophilin-like 8 molecule).•Our data indicate that BTNL8 costimulates Ag specific immune…”
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B7-H3 Enhances Tumor Immunity In Vivo by Costimulating Rapid Clonal Expansion of Antigen-Specific CD8+ Cytolytic T Cells by Luo, Liqun, Chapoval, Andrei I, Flies, Dallas B, Zhu, Gefeng, Hirano, Fumiya, Wang, Shengdian, Lau, Julie S, Dong, Haidong, Tamada, Koji, Flies, Andrew S, Liu, Yang, Chen, Lieping

“…B7-H3 is a B7 family molecule with T cell costimulatory function in vitro. The in vivo role of B7-H3 in the stimulation of tumor immunity is unclear. We report…”
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Activation of cytokine-producing and antitumor activities of natural killer cells and macrophages by engagement of Toll-like and NOD-like receptors by Qiu, Fu, Maniar, Amudhan, Diaz, Marco Quevedo, Chapoval, Andrei I, Medvedev, Andrei E

“…Macrophages and natural killer (NK) cells are important antitumor effectors by virtue of their ability to produce cytokines, chemokines and interferons (IFNs)…”
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Interleukin-7 Inhibits Tumor-Induced CD27-CD28- Suppressor T Cells: Implications for Cancer Immunotherapy by YUE ZHANG, PFANNENSTIEL, Lukas W, BOLESTA, Elzbieta, MONTES, Carolina L, XIAOYU ZHANG, CHAPOVAL, Andrei I, GARTENHAUS, Ronald B, STROME, Scott E, GASTMAN, Brian R

“…We have previously reported that many types of tumors can induce changes in human T cells that lead to the acquisition of suppressive function and phenotypic…”
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The anti-lymphoma activities of anti-CD137 monoclonal antibodies are enhanced in FcγRIII−/− mice by Sallin, Michelle A., Zhang, Xiaoyu, So, Edward C., Burch, Erin, Cai, Ling, Lin, Wei, Chapoval, Andrei I., Strome, Scott E.

“…Agonistic monoclonal antibodies (mAbs) directed against the co-signaling molecule CD137 (4-1BB) elicit potent anti-tumor immunity in mice. This anti-tumor…”
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Ligation of CD137 receptor prevents and reverses established anergy of CD8+cytolytic T lymphocytes in vivo by Wilcox, Ryan A., Tamada, Koji, Flies, Dallas B., Zhu, Gefeng, Chapoval, Andrei I., Blazar, Bruce R., Kast, W. Martin, Chen, Lieping

“…T-cell anergy is a tolerance mechanism defined as a hyporesponsive status of antigen-specific T cells upon prior antigen encounter and is believed to play a…”
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