Search Results - "Chaponda, Mike"

Measuring protective efficacy and quantifying the impact of drug resistance: A novel malaria chemoprevention trial design and methodology by Mousa, Andria, Cuomo-Dannenburg, Gina, Thompson, Hayley A, Chico, R Matthew, Beshir, Khalid B, Sutherland, Colin J, Schellenberg, David, Gosling, Roly, Alifrangis, Michael, Hocke, Emma Filtenborg, Hansson, Helle, Chopo-Pizarro, Ana, Mbacham, Wilfred F, Ali, Innocent M, Chaponda, Mike, Roper, Cally, Okell, Lucy C

“…Recently revised WHO guidelines on malaria chemoprevention have opened the door to more tailored implementation. Countries face choices on whether to replace…”
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Combining malaria vaccination with chemoprevention: a promising new approach to malaria control by Greenwood, Brian, Cairns, Matthew, Chaponda, Mike, Chico, R Matthew, Dicko, Alassane, Ouedraogo, Jean-Bosco, Phiri, Kamija S, Ter Kuile, Feiko O, Chandramohan, Daniel

“…Malaria control has stalled in a number of African countries and novel approaches to malaria control are needed for these areas. The encouraging results of a…”
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Malaria knowledge and bed net use in three transmission settings in southern Africa by Kanyangarara, Mufaro, Hamapumbu, Harry, Mamini, Edmore, Lupiya, James, Stevenson, Jennifer C, Mharakurwa, Sungano, Chaponda, Mike, Thuma, Philip E, Gwanzura, Lovemore, Munyati, Shungu, Mulenga, Modest, Norris, Douglas E, Moss, William J

“…Insecticide-treated nets (ITNs) reduce malaria morbidity and mortality in endemic areas. Despite increasing availability, the use of ITNs remains limited in…”
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The use of GPS data loggers to describe the impact of spatio-temporal movement patterns on malaria control in a high-transmission area of northern Zambia by Hast, Marisa, Searle, Kelly M, Chaponda, Mike, Lupiya, James, Lubinda, Jailos, Sikalima, Jay, Kobayashi, Tamaki, Shields, Timothy, Mulenga, Modest, Lessler, Justin, Moss, William J

“…Human movement is a driver of malaria transmission and has implications for sustainable malaria control. However, little research has been done on the impact…”
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High Plasmodium falciparum genetic diversity and temporal stability despite control efforts in high transmission settings along the international border between Zambia and the Democratic Republic of the Congo by Pringle, Julia C, Wesolowski, Amy, Berube, Sophie, Kobayashi, Tamaki, Gebhardt, Mary E, Mulenga, Modest, Chaponda, Mike, Bobanga, Thierry, Juliano, Jonathan J, Meshnick, Steven, Moss, William J, Carpi, Giovanna, Norris, Douglas E

“…While the utility of parasite genotyping for malaria elimination has been extensively documented in low to moderate transmission settings, it has been less…”
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The Search for Plasmodium falciparum histidine-rich protein 2/3 Deletions in Zambia and Implications for Plasmodium falciparum histidine-rich protein 2-Based Rapid Diagnostic Tests by Kobayashi, Tamaki, Sikalima, Jay, Parr, Jonathan B, Chaponda, Mike, Stevenson, Jennifer C, Thuma, Philip E, Mulenga, Modest, Meshnick, Steven R, Moss, William J, For The Southern And Central Africa International Centers Of Excellence For Malaria Research

“…We attempted to identify histidine-rich protein 2/3 ( ) deletions among rapid diagnostic test (RDT)-negative but PCR- or microscopy-positive -infected…”
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Individual and Household Level Risk Factors Associated with Malaria in Nchelenge District, a Region with Perennial Transmission: A Serial Cross-Sectional Study from 2012 to 2015 by Pinchoff, Jessie, Chaponda, Mike, Shields, Timothy M, Sichivula, James, Muleba, Mbanga, Mulenga, Modest, Kobayashi, Tamaki, Curriero, Frank C, Moss, William J

“…The scale-up of malaria control interventions has resulted in substantial declines in transmission in some but not all regions of sub-Saharan Africa…”
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Efficacy and safety of artemether-lumefantrine as treatment for Plasmodium falciparum uncomplicated malaria in adult patients on efavirenz-based antiretroviral therapy in Zambia: an open label non-randomized interventional trial by Banda, Clifford G, Chaponda, Mike, Mukaka, Mavuto, Mulenga, Modest, Hachizovu, Sebastian, Kabuya, Jean B, Mulenga, Joyce, Sikalima, Jay, Kalilani-Phiri, Linda, Terlouw, Dianne J, Khoo, Saye H, Lalloo, David G, Mwapasa, Victor

“…HIV-infected individuals on antiretroviral therapy (ART) require treatment with artemisinin-based combination therapy (ACT) when infected with malaria…”
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High burden of malaria following scale-up of control interventions in Nchelenge District, Luapula Province, Zambia by Mukonka, Victor M, Chanda, Emmanuel, Haque, Ubydul, Kamuliwo, Mulakwa, Mushinge, Gabriel, Chileshe, Jackson, Chibwe, Kennedy A, Norris, Douglas E, Mulenga, Modest, Chaponda, Mike, Muleba, Mbanga, Glass, Gregory E, Moss, William J

“…Malaria control interventions have been scaled-up in Zambia in conjunction with a malaria surveillance system. Although substantial progress has been achieved…”
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The prioritisation of curable sexually transmitted infections among pregnant women in Zambia and Papua New Guinea: Qualitative insights by Vallely, Lisa M, Kapungu, Kelvin, Mengi, Alice, Chaponda, Mike, Chico, R Matthew, Riddell, Michaela A, Vallely, Andrew J, Pomat, William, Cignacco, Eva, Low, Nicola, Kelly-Hanku, Angela

“…Curable sexually transmitted infections (STIs) are neglected in public health policy, services and society at large. Effective interventions are available for…”
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Distinct Antibody Signatures Associated with Different Malaria Transmission Intensities in Zambia and Zimbabwe by Kobayashi, Tamaki, Jain, Aarti, Liang, Li, Obiero, Joshua M, Hamapumbu, Harry, Stevenson, Jennifer C, Thuma, Philip E, Lupiya, James, Chaponda, Mike, Mulenga, Modest, Mamini, Edmore, Mharakurwa, Sungano, Gwanzura, Lovemore, Munyati, Shungu, Mutambu, Susan, Felgner, Philip, Davies, D Huw, Moss, William J

“…Antibodies to are specific biomarkers that can be used to monitor parasite exposure over broader time frames than microscopy, rapid diagnostic tests, or…”
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Safety and efficacy of dihydroartemisinin-piperaquine versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Zambian children by Nambozi, Michael, Van Geertruyden, Jean-Pierre, Hachizovu, Sebastian, Chaponda, Mike, Mukwamataba, Doreen, Mulenga, Modest, Ubben, David, D'Alessandro, Umberto

“…Malaria in Zambia remains a public health and developmental challenge, affecting mostly children under five and pregnant women. In 2002, the first-line…”
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SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART) by Maitland, Kathryn, Hamaluba, Mainga, Obonyo, Nchafatso, Oguda, Emmanuel, Mogoka, Christabel, Williams, Thomas N, Chaponda, Mike, Miti, Sam, Kamavu, Luc Kambale, Jonathan Gwasupika, Jonathan, Connon, Roisin, Gibb, Diana M, Dondorp, Arjen, Day, Nick, White, Nick, Walker, A Sarah, George, Elizabeth C

“…Even on the best antimalarial treatments (injectable artesunate) African children with severe malaria have poor outcomes with most deaths occurring early in…”
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EFFICACY AND SAFETY OF ARTEMISININ-BASED COMBINATION THERAPIES IN PEOPLE WITH PLASMODIUM FALCIPARUM MALARIA RECEIVING ANTIRETROVIRAL THERAPY IN ZAMBIA by Chaponda, Mike

“…BackgroundThe coverage of Artemisinin-based Combination Therapies (ACTs) for treatment of malaria and antiretroviral therapy (ART) is increasing rapidly in…”
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Congenital malformations in sub-Saharan Africa—warnings of a silent epidemic? by Sié, Ali, Hanefeld, Johanna, Chaponda, Mike, Chico, R Matthew, LeDoare, Kirsty, Mayaud, Philippe, Drexler, Jan Felix, Jaenisch, Thomas

“…There was no epidemiological surveillance for Zika virus established at the time, since the African-origin virus was previously endemic in Africa and Asia…”
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The Impact of 3 Years of Targeted Indoor Residual Spraying With Pirimiphos-Methyl on Malaria Parasite Prevalence in a High-Transmission Area of Northern Zambia by Hast, Marisa A, Chaponda, Mike, Muleba, Mbanga, Kabuya, Jean-Bertin, Lupiya, James, Kobayashi, Tamaki, Shields, Timothy, Lessler, Justin, Mulenga, Modest, Stevenson, Jennifer C, Norris, Douglas E, Moss, William J

“…Abstract Malaria transmission in northern Zambia has increased in the past decade, despite malaria control activities. Evidence-based intervention strategies…”
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The Impact of Household and Community Indoor Residual Spray Coverage with Fludora Fusion in a High Malaria Transmission Setting in Northern Zambia by Ferriss, Ellen, Chaponda, Mike, Muleba, Mbanga, Kabuya, Jean-Bertin, Lupiya, James Sichivula, Riley, Christina, Winters, Anna, Moulton, Lawrence H, Mulenga, Modest, Norris, Douglas E, Moss, William J

“…Zambia's National Malaria Elimination Program transitioned to Fludora Fusion in 2019 for annual indoor residual spraying (IRS) in Nchelenge District, an area…”
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Measuring protective efficacy and quantifying the impact of drug resistance: A novel malaria chemoprevention trial design and methodology by Andria Mousa, Gina Cuomo-Dannenburg, Hayley A. Thompson, R. Matthew Chico, Khalid B. Beshir, Colin J. Sutherland, David Schellenberg, Roly Gosling, Michael Alifrangis, Emma Filtenborg Hocke, Helle Hansson, Ana Chopo-Pizarro, Wilfred F. Mbacham, Innocent M. Ali, Mike Chaponda, Cally Roper, Lucy C. Okell

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RTS,S/AS01 malaria vaccine mismatch observed among Plasmodium falciparum isolates from southern and central Africa and globally by Pringle, Julia C., Carpi, Giovanna, Almagro-Garcia, Jacob, Zhu, Sha Joe, Kobayashi, Tamaki, Mulenga, Modest, Bobanga, Thierry, Chaponda, Mike, Moss, William J., Norris, Douglas E.

“…The RTS,S/AS01 malaria vaccine encompasses the central repeats and C-terminal of Plasmodium falciparum circumsporozoite protein (PfCSP). Although no Phase II…”
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The Impact of Three Years of Targeted Indoor Residual Spraying with Pirimiphos-Methyl on Household Vector Abundance in a High Malaria Transmission Area of Northern Zambia by Hast, Marisa A, Stevenson, Jennifer C, Muleba, Mbanga, Chaponda, Mike, Kabuya, Jean-Bertin, Mulenga, Modest, Shields, Timothy, Moss, William J, Norris, Douglas E

“…The global malaria burden has decreased substantially, but gains have been uneven both within and between countries. In Zambia, the malaria burden remains high…”
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