Search Results - "Chapman, V M"
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Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS-M
Published in Nature genetics (01-09-1996)“…Normal mammalian development requires a diploid combination of both haploid parental genomes. Uniparental disomy for certain segments of specific chromosomes…”
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Cyclin-dependent kinase 6 (CDK6) amplification in human gliomas identified using two-dimensional separation of genomic DNA
Published in Cancer research (Chicago, Ill.) (01-04-1997)“…DNA amplification is a common mechanism invoked by many human tumors to elicit overexpression of genes whose products are involved in drug resistance or cell…”
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The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus
Published in Nature (London) (01-09-1988)“…Mice carrying mutations at the W locus located on chromosome 5 are characterized by severe macrocytic anaemia, lack of hair pigmentation and sterility…”
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Recovery of Induced Mutations for X Chromosome-Linked Muscular Dystrophy in Mice
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-1989)“…We have used elevated levels of plasma creatine phosphokinase activity to identify muscular dystrophy phenotypes in mice and to screen the progeny of chemical…”
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Platelet-Derived Growth Factor Receptor α-Subunit Gene (Pdgfra) is Deleted in the Mouse Patch (Ph) Mutation
Published in Proceedings of the National Academy of Sciences - PNAS (01-01-1991)“…Platelet-derived growth factor receptors are composed of two subunits (α and β) that associate with one another to form three functionally active dimeric…”
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Location of the mouse complement factor H gene (cfh) by FISH analysis and replication R-banding
Published in Cytogenetics and cell genetics (01-01-1992)“…A technique for replication R- and G-banding of mouse lymphocyte chromosomes was developed, and the replication R-banding pattern was analyzed. Optimal banding…”
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Genetic Basis of X-Y Chromosome Dissociation and Male Sterility in Interspecific Hybrids
Published in Proceedings of the National Academy of Sciences - PNAS (01-06-1991)“…A high frequency of X-Y chromosome dissociation (95%) was found at first meiotic metaphase (MI) in spermatocytes of interspecific hybrids between laboratory…”
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Identification of an imprinted U2af binding protein related sequence on mouse chromosome 11 using the RLGS method
Published in Nature genetics (01-01-1994)“…A new imprinted gene has been discovered in mice using the technique of restriction landmark genomic scanning (RLGS) with methylation sensitive enzymes. Eight…”
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Mechanisms of X-Chromosome Regulation
Published in Annual review of genetics (01-01-1988)Get full text
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Construction of random small-insert genomic libraries highly enriched for simple sequence repeats
Published in Nucleic acids research (11-08-1993)“…We present an efficient method for construction of random small-insert genomic libraries enriched for (CA) sub(n) repeats. The method involves fragmentation of…”
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The effect of hypothermia on calculated values using saline and automated air tonometry
Published in Journal of cardiothoracic and vascular anesthesia (01-06-2002)“…Objective: To quantify in vitro the effect of hypothermia on results obtained when performing automated air tonometry (Tonocap, Datex-Ohmeda, Instrumentarium…”
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Differences in DNA methylation during oogenesis and spermatogenesis and their persistence during early embryogenesis in the mouse
Published in Genes & development (01-12-1987)“…We have examined the relative methylation levels of several dispersed repeated and low-copy-number gene sequences during gametogenesis and early embryogenesis…”
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Inactivation of the Zfx Gene on the Mouse X Chromosome
Published in Proceedings of the National Academy of Sciences - PNAS (01-06-1991)“…ZFX, an X chromosome-linked gene encoding a zinc-finger protein, has previously been shown to escape X inactivation in humans. Here we report studies of the…”
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CpG island promoter region methylation patterns of the inactive-X-chromosome hypoxanthine phosphoribosyltransferase (Hprt) gene
Published in Molecular and Cellular Biology (01-12-1994)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Close physical linkage of the FLT1 and FLT3 genes on chromosome 13 in man and chromosome 5 in mouse
Published in Oncogene (01-01-1993)“…Receptor-type tyrosine kinases (RTK) with five or seven immunoglobulin-like domains in their extracellular region are encoded by genes grouped in clusters. In…”
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A Genetic Linkage Map of the Mouse Using Restriction Landmark Genomic Scanning (RLGS)
Published in Genetics (Austin) (01-12-1994)“…We have developed a multiplex method of genome analysis, restriction landmark genomic scanning (RLGS) that has been used to construct genetic maps in mice…”
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Application of fluorescence in situ hybridization in genome analysis of the mouse
Published in Electrophoresis (1995)“…Fluorescence in situ hybridization (FISH) is an effective technique for localizing cloned DNA probes directly onto metaphase chromosomes. Human genome mapping…”
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Undermethylation of structural gene sequences in extraembryonic lineages of the mouse
Published in Developmental biology (01-10-1986)“…The first two lineages to differentiate in the mouse embryo are the trophectoderm and primitive endoderm, which give rise to various extraembryonic structures…”
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Inactive allele-specific methylation and chromatin structure of the imprinted gene U2af1-rs1 on mouse chromosome 11
Published in Genomics (San Diego, Calif.) (01-07-1996)“…The imprinted U2af1-rs1 gene that maps to mouse chromosome 11 is predominately expressed from the paternal allele. We examined the methylation of genomic…”
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