Search Results - "Chaplin, P.J"

The comparative efficacy of CTLA-4 and L-selectin targeted DNA vaccines in mice and sheep by Drew, Damien R., Boyle, J.S., Lew, A.M., Lightowlers, M.W., Chaplin, P.J., Strugnell, R.A.

“…The access of antigens to antigen presenting cells (APCs) appears to be a rate-limiting step in the generation of immune responses to DNA vaccines. The…”
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Local immune responses to influenza antigen are synergistically enhanced by the adjuvant ISCOMATRIX by Windon, R.G., Chaplin, P.J., McWaters, P., Tavarnesi, M., Tzatzaris, M., Kimpton, W.G., Cahill, R.N.P., Beezum, L., Coulter, A., Drane, D., Sjölander, A., Pearse, M., Scheerlinck, J-P.Y., Tennent, J.M.

“…The peripheral (draining) lymph node, as the primary site of immune induction, determines the course of systemic responses to an injected antigen. Lymphatic…”
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Characterisation of monoclonal antibodies to ovine interleukin-6 and the development of a sensitive capture ELISA by McWaters, P, Hurst, L, Chaplin, P.J, Collins, R.A, Wood, P.R, Scheerlinck, J.-P.Y

“…A purified recombinant ovine (rOv) interleukin-6 (IL-6) was used to generate specific murine monoclonal antibodies (mAbs) and a polyclonal rabbit antisera to…”
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Influence of IL-12 on interferon- γ production by bovine leucocyte subsets in response to bovine respiratory syncytial virus by Collins, R.A, Camon, E.B, Chaplin, P.J, Howard, C.J

“…The cytokine IL-12 is a key molecule in the regulation of CD4+T cell development and specifically potentiates the development of T helper 1 responses in mouse…”
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Cloning and biologic activities of a bovine interferon-alpha isolated from the epithelium of a rotavirus-infected calf by Chaplin, P J, Entrican, G, Gelder, K I, Collins, R A

“…A cDNA encoding a distinct bovine (Bo) interferon (IFN) alpha, designated BoIFN-alpha E, was generated from gut epithelial cells isolated from a…”
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