Search Results - "Chaplin, MJ"

Differentiation of prion protein glycoforms from naturally occurring sheep scrapie, sheep-passaged scrapie strains (CH1641 and SSBP1), bovine spongiform encephalopathy (BSE) cases and Romney and Cheviot breed sheep experimentally inoculated with BSE using two monoclonal antibodies by STACK, Michael James, CHAPLIN, Melanie Jane, CLARK, Jemma

“…A panel of ruminant brain tissues were subjected to a Western immunoblotting technique using two monoclonal antibodies (mAbs). The resultant prion protein…”
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Four BSE cases with an L‐BSE molecular profile in cattle from Great Britain by Stack, M. J., Chaplin, M. J., Davis, L. A., Everitt, S., Simmons, M. M., Windl, O., Hope, J., Burke, P.

“…Bovine spongiform encephalopathy (BSE) is a prion disease of cattle which was first observed in Great Britain (GB) in 1986. Throughout the subsequent BSE…”
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Postmortem diagnosis of preclinical and clinical scrapie in sheep by the detection of disease-associated PrP in their rectal mucosa by González, L., Dagleish, M. P., Bellworthy, S. J., Sisó, S., Stack, M. J., Chaplin, M. J., Davis, L. A., Hawkins, S. A. C., Hughes, J., Jeffrey, M.

“…Samples of tissue from the central nervous system (CNS), the lymphoreticular system (LRS) and the rectal mucosa of a large number of scrapie-exposed sheep,…”
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Preliminary observations on the pathogenesis of experimental bovine spongiform encephalopathy (BSE): an update by Wells, G. A. H., Hawkins, S. A. C., Green, R. B., Austin, A. R., Dexter, I., Spencer, Y. I., Chaplin, M. J., Stack, M. J., Dawson, M.

“…Further preliminary observations are reported of an experiment to examine the spread of infectivity and the occurrence of pathological changes in cattle…”
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Experimental transmission of chronic wasting disease agent from mule deer to cattle by the intracerebral route by Hamir, A.N, Kunkle, R.A, Cutlip, R.C, Miller, J.M, O'Rourke, K.I, Williams, E.S, Miller, M.W, Stack, M.J, Chaplin, M.J, Richt, J.A

“…This communication reports final observations on experimental transmission of chronic wasting disease (CWD) from mule deer to cattle by the intracerebral…”
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Diagnosis of preclinical scrapie in samples of rectal mucosa by González, Lorenzo, Jeffrey, Martin, SisÓ, Sílvia, Martin, Stuart, Bellworthy, Sue J., Stack, Mick J., Chaplin, Melanie J., Davis, Linda, Dagleish, Mark P., Reid, Hugh W.

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Experimental Bovine Spongiform Encephalopathy: Detection of PrP super(Sc in the Small Intestine Relative to Exposure Dose and Age) by Stack, MJ, Moore, S J, Vidal-Diez, A, Arnold, ME, Jones, E M, Spencer, YI, Webb, P, Spiropoulos, J, Powell, L, Bellerby, P, Thurston, L, Cooper, J, Chaplin, MJ, Davis, LA, Everitt, S, Focosi-Snyman, R, Hawkins, SAC, Simmons, M M, Wells, GAH

“…European regulations for the control of bovine spongiform encephalopathy (BSE) decree destruction of the intestines from slaughtered cattle, therefore…”
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Transmission of sheep scrapie to elk (Cervus elaphus nelsoni) by intracerebral inoculation: final outcome of the experiment by Hamir, Amir N, Miller, Janice M, Cutlip, Randall C, Kunkle, Robert A, Jenny, Allen L, Stack, Mick J, Chaplin, Melanie J, Richt, Juergen A

“…This is a final report of an experimental transmission of sheep scrapie agent by intracerebral inoculation to Rocky Mountain elk (Cervus elaphus nelsoni). It…”
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Experimental inoculation of scrapie and chronic wasting disease agents in raccoons (Procyon lotor) by Hamir, A. N., Miller, J. M., Cutlip, R. C., Stack, M. J., Chaplin, M. J., Jenny, A. L., Williams, E. S.

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Preliminary findings on the experimental transmission of chronic wasting disease agent of mule deer to cattle by Hamir, AN, Cutlip, RC, Miller, JM, Williams, ES, Stack, MJ, Miller, MW, O'Rourke, KI, Chaplin, MJ

“…National Animal Disease Center, ARS, USDA, Ames, IA 50010, USA. To determine the transmissibility of chronic wasting disease (CWD) to cattle and to provide…”
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Transmission of Transmissible Mink Encephalopathy to Raccoons (Procyon Lotor) by Intracerebral Inoculation by Hamir, Amir N, Miller, Janice M, O'Rourke, Katherine I, Bartz, Jason C, Stack, Mick J, Chaplin, Melaine J

“…To determine the transmissibility of transmissible mink encephalopathy (TME) agent to raccoons and to provide information about clinical course, lesions, and…”
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A short purification process for quantitative isolation of PrPSc from naturally occurring and experimental transmissible spongiform encephalopathies by Polymenidou, Magdalini, Verghese-Nikolakaki, Susan, Groschup, Martin, Chaplin, Melanie J, Stack, Mick J, Plaitakis, Andreas, Sklaviadis, Theodoros

“…Transmissible spongiform encephalopathies (TSEs) are neurodegenerative diseases affecting both humans and animals. They are associated with post-translational…”
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Evaluation of the effects of controlled autolysis on the immunodetection of PrPSc by immunoblotting and immunohistochemistry from natural cases of scrapie and bse by Chaplin, M.J., Barlow, N., Ryder, S., Simmons, M.M., Spencer, Y., Hughes, R., Stack, M.J.

“…Seventeen clinically suspect scrapie sheep, and twelve suspected bse -affected cattle were confirmed using routine histopathological examination by the…”
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Failure to detect abnormal prion protein and scrapie-associated fibrils 6 wk after intracerebral inoculation of genetically susceptible sheep with scrapie agent by Hamir, A.N, Miller, J.M, Stack, M.J, Chaplin, M.J

“…Detection of the scrapie-associated protease-resistant prion protein (PrPres) in sheep brains in the early phase after intracerebral inoculation of the scrapie…”
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Neuroaxonal dystrophy in raccoons (Procyon lotor) from Iowa by Hamir, AN, Miller, JM, Stack, MJ, Chaplin, MJ, Cutlip, RC

“…National Animal Disease Center, ARS, USDA, Ames, IA, USA. During a 12-month period (1998-1999), microscopic evidence of neuroaxonal dystrophy (NAD) in medullae…”
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Diagnosis of preclinical and subclinical scrapie in a naturally infected sheep flock utilizing currently available postmortem diagnostic techniques by Hamir, AN, Miller, JM, Schmerr, MJ, Stack, MJ, Chaplin, MJ, Cutlip, RC

“…National Animal Disease Center, ARS, USDA, Ames, IA 50010, USA. Scrapie is a naturally occurring transmissible encephalopathy of sheep and goats. Currently…”
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Idiopathic disseminated intracytoplasmic neuronal vacuolation in a neonatal Holstein calf born in the USA by Hamir, AN, Habecker, P, Jenny, A, Hutto, D, Stack, MJ, Chaplin, MJ, Stasko, J

“…National Animal Disease Center, ARS, USDA, Ames, IA 50010, USA. Histopathologic, immunohistochemical, and ultrastructural evaluations were made of a 6-day-old…”
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Resistance of domestic cats to a US sheep scrapie agent by intracerebral route by Hamir, AN, Clark, WW, Sutton, DL, Miller, JM, Stack, MJ, Chaplin, MJ, Jenny, AL

“…National Animal Disease Center, ARS, USDA, Ames, IA 50010, USA. Feline spongiform encephalopathy (FSE) is thought to have resulted from consumption of food…”
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Scrapie associated fibril detection from formaldehyde fixed brain tissue in natural cases of ovine scrapie by Chaplin, M.J., Aldrich, A.D., Stack, M.J.

“…The medulla oblongata of the brains of 71 scrapie-suspect cases were routinely fixed in 10 per cent formal saline and assessed for vacuolation on HE-stained…”
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The distribution of scrapie-associated fibrils in neural and non-neural tissues of advanced clinical cases of natural scrapie in sheep by Stack, M.J., Chaplin, M.J., Aldrich, A.M., Davis, L.A.

“…The distribution of scrapie-associated fibrils (SAFs) throughout four brain regions, the pituitary gland, along the whole length of the spinal cord and in the…”
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