Search Results - "Chapalamadugu, Kalyan C"
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Nampt activator P7C3 ameliorates diabetes and improves skeletal muscle function modulating cell metabolism and lipid mediators
Published in Journal of cachexia, sarcopenia and muscle (01-04-2022)“…Background Nicotinamide phosphoribosyltransferase (Nampt), a key enzyme in NAD salvage pathway is decreased in metabolic diseases, and its precise role in…”
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Maternal bisphenol a exposure impacts the fetal heart transcriptome
Published in PloS one (25-02-2014)“…Conditions during fetal development influence health and disease in adulthood, especially during critical windows of organogenesis. Fetal exposure to the…”
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MicroRNA-301a mediated regulation of Kv4.2 in diabetes: identification of key modulators
Published in PloS one (03-04-2013)“…Diabetes is a metabolic disorder that ultimately results in major pathophysiological complications in the cardiovascular system. Diabetics are predisposed to…”
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Integrated approach for smart implantable cardioverter defibrillator (ICD) device with real time ECG monitoring: use of flexible sensors for localized arrhythmia sensing and stimulation
Published in Frontiers in physiology (24-10-2013)“…Arrhythmias are the most common cause of death associated with sudden death and are common in US and worldwide. Cardiac resynchronization therapy (CRT),…”
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5
Smad7 interrupts TGF-β signaling in intestinal macrophages and promotes inflammatory activation of these cells during necrotizing enterocolitis
Published in Pediatric research (01-06-2016)“…Background: Necrotizing enterocolitis (NEC) is an inflammatory bowel necrosis of premature infants. Based on our recent findings of increased Smad7 expression…”
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Cardioprotective Effects of 1-(3,6-Dibromo-carbazol-9-yl)-3-Phenylamino-Propan-2-Ol in Diabetic Hearts via Nicotinamide Phosphoribosyltransferase Activation
Published in The Journal of pharmacology and experimental therapeutics (01-08-2022)“…Diabetes is associated with increased cardiac injury and sudden death. Nicotinamide phosphoribosyltransferase (Nampt) is an essential enzyme for the NAD…”
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Kvβ1.1 (AKR6A8) senses pyridine nucleotide changes in the mouse heart and modulates cardiac electrical activity
Published in American journal of physiology. Heart and circulatory physiology (01-03-2017)“…The present study investigates the physiological role of Kvβ1 subunit for sensing pyridine nucleotide (NADH/NAD+) changes in the heart. We used Kvβ1.1 knockout…”
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Metabolic regulation of Kv channels and cardiac repolarization by Kvβ2 subunits
Published in Journal of molecular and cellular cardiology (01-12-2019)“…Voltage-gated potassium (Kv) channels control myocardial repolarization. Pore-forming Kvα proteins associate with intracellular Kvβ subunits, which bind…”
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High level of oxygen treatment causes cardiotoxicity with arrhythmias and redox modulation
Published in Toxicology and applied pharmacology (01-01-2015)“…Hyperoxia exposure in mice leads to cardiac hypertrophy and voltage-gated potassium (Kv) channel remodeling. Because redox balance of pyridine nucleotides…”
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Analysis of Longissimus thoracis Protein Expression Associated with Variation in Carcass Quality Grade and Marbling of Beef Cattle Raised in the Pacific Northwestern United States
Published in Journal of agricultural and food chemistry (22-02-2017)“…Longissimus thoracis (LD) samples from 500 cattle were screened for protein expression differences relative to carcass quality grade. The LD of the top 5% (low…”
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Deletion of Kvβ1.1 subunit leads to electrical and haemodynamic changes causing cardiac hypertrophy in female murine hearts
Published in Experimental physiology (01-04-2016)“…New Findings What is the central question of this study? The goal of this study was to evaluate sex differences and the role of the potassium channel β1 (Kvβ1)…”
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Pleiotropic effects of metformin to rescue statin-induced muscle injury and insulin resistance: A proposed mechanism and potential clinical implications
Published in Medical hypotheses (01-09-2017)“…The 2013 American Heart Association Blood Cholesterol Guidelines increased the number of patients recommended for statin therapy in the United States to…”
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Adipocyte differentiation-specific gene transcriptional response to C18 unsaturated fatty acids plus insulin
Published in Pflügers Archiv (01-03-2012)“…Adipocyte differentiation (AD) and AD-specific gene expression was studied in 3T3-L1 cells in response to oleic acid (OA) or linoleic acid (LA) alone and in…”
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Dietary carbohydrate level affects transcription factor expression that regulates skeletal muscle myogenesis in rainbow trout
Published in Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology (01-05-2009)“…Understanding the effects of dietary carbohydrates on transcription factors that regulate myogenesis provides insight into the role of nutrient sensing by…”
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Oncorhynchus mykiss pax7 sequence variations with comparative analyses against other teleost species
Published in SpringerPlus (17-06-2015)“…The paired box-7 ( pax7 ) transcription factor expressed in satellite cells (SCs) is an essential regulator of skeletal muscle growth and regeneration in…”
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Interactions of muscle regulatory factors and isoforms of insulin growth factor‐1 in the muscle regenerative process
Published in The Journal of physiology (01-06-2009)Get full text
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Taenia taeniaeformis: Effectiveness of staining oncospheres is related to both temperature of treatment and molecular weight of dyes utilized
Published in Veterinary parasitology (14-02-2008)“…Methods to determine viability of taeniid oncospheres following treatments with potential lethality have practical application in efforts to control…”
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Kvβ2 deletion results in hindlimb muscle fibre type switching and enhanced endurance capabilities
Published in The FASEB journal (01-04-2019)“…The Kvβ2 subunit, a member of the Kv (voltage‐gated potassium channel) auxiliary subunits is a dynamic protein interacting with many protein. Previous research…”
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Kvβ2 Subunit Regulates Cardiac Levels of SLC41a3 a Sodium‐Magnesium Transporter
Published in The FASEB journal (01-04-2018)“…Background Clinical evidence has demonstrated that administration of magnesium can provide cardioprotective benefits during acute MI as well as suppression of…”
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Deletion of Kvβ2 Alters Murine Skeletal Muscle Morphology and Phenotype
Published in The FASEB journal (01-04-2017)“…Abstract only…”
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