Search Results - "Chao, K S Clifford"

Protein phosphatase 2A inactivation induces microsatellite instability, neoantigen production and immune response by Yen, Yu-Ting, Chien, May, Wu, Pei-Yi, Ho, Chi-Chang, Ho, Chun-Te, Huang, Kevin Chih-Yang, Chiang, Shu-Fen, Chao, K. S. Clifford, Chen, William Tzu-Liang, Hung, Shih-Chieh

“…Microsatellite-instable (MSI), a predictive biomarker for immune checkpoint blockade (ICB) response, is caused by mismatch repair deficiency (MMRd) that occurs…”
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Engineered sTRAIL-armed MSCs overcome STING deficiency to enhance the therapeutic efficacy of radiotherapy for immune checkpoint blockade by Huang, Kevin Chih-Yang, Chiang, Shu-Fen, Chang, Hsin-Yu, Chen, William Tzu-Liang, Yang, Pei-Chen, Chen, Tsung-Wei, Liang, Ji-An, Shiau, An‑Cheng, Ke, Tao-Wei, Clifford Chao, K. S.

“…Radiotherapy (RT) mainly elicits antitumor immunity via the cGAS/STING axis for type I interferon (IFN) production. However, dysregulation of cGAS/STING…”
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Prognostic relevance of programmed cell death 1 ligand 2 (PDCD1LG2/PD-L2) in patients with advanced stage colon carcinoma treated with chemotherapy by Huang, Kevin Chih-Yang, Chiang, Shu-Fen, Chen, Tsung-Wei, Chen, William Tzu-Liang, Yang, Pei-Chen, Ke, Tao-Wei, Chao, K. S. Clifford

“…Colorectal cancer (CRC) is the leading cause of cancer-related mortality worldwide. Although the role of tumor programmed cell death 1 ligand 1 (PD-L1) in…”
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10-year follow-up of treatment outcomes in patients with early stage breast cancer and clinically negative axillary nodes treated with tangential breast irradiation following sentinel lymph node dissection or axillary clearance by Wernicke, A. Gabriella, Goodman, Robert L, Turner, Bruce C, Komarnicky, Lydia T, Curran, Walter J, Christos, Paul J, Khan, Imraan, Vandris, Katherine, Parashar, Bhupesh, Nori, Dattatreyudu, Chao, K. S. Clifford

“…We compare long-term outcomes in patients with node negative early stage breast cancer treated with breast radiotherapy (RT) without the axillary RT field…”
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Surveillance, Epidemiology, and End Results-based analysis of the impact of preoperative or postoperative radiotherapy on survival outcomes for T3N0 rectal cancer by Peng, Luke C, Milsom, Jeffrey, Garrett, Kelly, Nandakumar, Govind, Coplowitz, Shana, Parashar, Bhupesh, Nori, Dattatreyudu, Clifford Chao, K.S, Wernicke, A.G

“…Abstract Purpose : Preoperative chemoradiation has been established as standard of care for T3/T4 node-positive rectal cancer. Recent work, however, has called…”
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Comparison of 2D Radiographic Images and 3D Cone Beam Computed Tomography for Positioning Head-and-Neck Radiotherapy Patients by Li, Heng, Ph.D, Zhu, X. Ronald, Ph.D, Zhang, Lifei, Ph.D, Dong, Lei, Ph.D, Tung, Sam, M.S, Ahamad, Anesa, M.D, Chao, K. S. Clifford, M.D, Morrison, William H., M.D, Rosenthal, David I., M.D, Schwartz, David L., M.D, Mohan, Radhe, Ph.D, Garden, Adam S., M.D

“…Purpose To assess the positioning accuracy using two-dimensional kilovoltage (2DkV) imaging and three-dimensional cone beam CT (CBCT) in patients with head and…”
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The cost-effectiveness of surgical resection and cesium-131 intraoperative brachytherapy versus surgical resection and stereotactic radiosurgery in the treatment of metastatic brain tumors by Wernicke, A. Gabriella, Yondorf, Menachem Z., Parashar, Bhupesh, Nori, Dattatreyudu, Clifford Chao, K. S., Boockvar, John A., Pannullo, Susan, Stieg, Philip, Schwartz, Theodore H.

“…This study aims to evaluate the cost-effectiveness of surgical resection (S) and Cesium-131 (Cs-131) [S + Cs-131] intraoperative brachytherapy versus S and…”
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PTEN regulates DNA replication progression and stalled fork recovery by He, Jinxue, Kang, Xi, Yin, Yuxin, Chao, K. S. Clifford, Shen, Wen H.

“…Faithful DNA replication is a cornerstone of genomic integrity. PTEN plays multiple roles in genome protection and tumour suppression. Here we report on the…”
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Transforming Growth Factor β-1 (TGF-β1) Is a Serum Biomarker of Radiation Induced Fibrosis in Patients Treated With Intracavitary Accelerated Partial Breast Irradiation: Preliminary Results of a Prospective Study by Boothe, Dustin L., MD, Coplowitz, Shana, MD, Greenwood, Eleni, MD, Barney, Christian L., MD, Christos, Paul J., DrPH, MS, Parashar, Bhupesh, MD, Nori, Dattatreyudu, MD, Chao, K. S. Clifford, MD, Wernicke, A. Gabriella, MD, MSc

“…Purpose To examine a relationship between serum transforming growth factor β -1 (TGF-β1) values and radiation-induced fibrosis (RIF). Methods and Materials We…”
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Predicting the Risk of Secondary Lung Malignancies Associated With Whole-Breast Radiation Therapy by Ng, John, M.D, Shuryak, Igor, M.D., Ph.D, Xu, Yanguang, Ph.D, Clifford Chao, K.S., M.D, Brenner, David J., Ph.D., D.Sc, Burri, Ryan J., M.D

“…Purpose The risk of secondary lung malignancy (SLM) is a significant concern for women treated with whole-breast radiation therapy after breast-conserving…”
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Decitabine Augments Chemotherapy-Induced PD-L1 Upregulation for PD-L1 Blockade in Colorectal Cancer by Huang, Kevin Chih-Yang, Chiang, Shu-Fen, Chen, William Tzu-Liang, Chen, Tsung-Wei, Hu, Ching-Han, Yang, Pei-Chen, Ke, Tao-Wei, Chao, K S Clifford

“…Programmed cell death-1 (PD-1) has demonstrated impressive clinical outcomes in several malignancies, but its therapeutic efficacy in the majority of…”
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Limited resection followed by intraoperative seed implantation is comparable to stereotactic body radiotherapy for solitary lung cancer by Parashar, Bhupesh, Patel, Priti, Monni, Stefano, Singh, Prabhsimranjot, Sood, Nikki, Trichter, Samuel, Sabbas, Albert, Wernicke, A. Gabriella, Nori, Dattatreyudu, Chao, K. S. Clifford

“…BACKGROUND: The objective of this study was to compare the outcomes of patients who underwent wedge resection plus intraoperative brachytherapy versus patients…”
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Outcomes of gamma knife radiosurgery, bi-modality & tri-modality treatment regimens for patients with one or multiple brain metastases: the Columbia University Medical Center experience by Wang, Tony J. C., Saad, Shumaila, Qureshi, Yasir H., Jani, Ashish, Isaacson, Steven R., Sisti, Michael B., Bruce, Jeffrey N., McKhann, Guy M., Lesser, Jeraldine, Cheng, Simon K., Clifford Chao, K. S., Lassman, Andrew B.

“…Optimal treatment of brain metastases (BMs) is debatable. However, surgery or gamma knife radiosurgery (GKRS) improves survival when combined with whole brain…”
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Clinical significance of programmed death 1 ligand-1 (CD274/PD-L1) and intra-tumoral CD8+ T-cell infiltration in stage II–III colorectal cancer by Huang, Chih-Yang, Chiang, Shu-Fen, Ke, Tao-Wei, Chen, Tsung-Wei, You, Ying-Shu, Chen, William Tzu-Liang, Chao, K. S. Clifford

“…Programmed cell death-1 (PDCD1/PD-1) and its ligand programmed cell death 1 ligand 1 (CD274/PD-L1) have been reported to suppress anti-tumor T cell-mediated…”
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Prognostic relevance of programmed cell death-ligand 1 expression and CD8+ TILs in rectal cancer patients before and after neoadjuvant chemoradiotherapy by Chen, Tsung-Wei, Huang, Kevin Chih-Yang, Chiang, Shu-Fen, Chen, William Tzu-Liang, Ke, Tao-Wei, Chao, K. S. Clifford

“…Purpose/background Radiotherapy has been recently reported to boost the therapeutic response of immune checkpoint blockade (ICB); however, few studies have…”
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Panoramic cone beam computed tomography by Chang, Jenghwa, Zhou, Lili, Wang, Song, Clifford Chao, K. S.

“…Purpose: Cone-beam computed tomography (CBCT) is the main imaging tool for image-guided radiotherapy but its functionality is limited by a small imaging volume…”
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Polymorphism of formyl peptide receptor 1 (FPR1) reduces the therapeutic efficiency and antitumor immunity after neoadjuvant chemoradiotherapy (CCRT) treatment in locally advanced rectal cancer by Chiang, Shu-Fen, Huang, Kevin Chih-Yang, Chen, William Tzu-Liang, Chen, Tsung-Wei, Ke, Tao-Wei, Chao, K. S. Clifford

“…Immunosurveillance and immunoscavenging prompted by preoperative chemoradiotherapy (CCRT) may contribute to improve local control and increase survival…”
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Dual inhibition of TGFβ signaling and CSF1/CSF1R reprograms tumor-infiltrating macrophages and improves response to chemotherapy via suppressing PD-L1 by Chen, Tsung-Wei, Hung, Wei-Ze, Chiang, Shu-Fen, Chen, William Tzu-Liang, Ke, Tao-Wei, Liang, Ji-An, Huang, Chih-Yang, Yang, Pei-Chen, Huang, Kevin Chih-Yang, Chao, K.S. Clifford

“…TGFβ contributes to chemoresistance in advanced colorectal cancer (CRC) via diverse immune-microenvironment mechanisms. Here, we found that cancer cell…”
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Prostate-specific membrane antigen expression in tumor-associated vasculature of breast cancers by Wernicke, Alla Gabriella, Varma, Sonal, Greenwood, Eleni A., Christos, Paul J., Chao, K. S. Clifford, Liu, He, Bander, Neil H., Shin, Sandra J.

“…Prostate‐specific membrane antigen (PSMA) has been found to be expressed in the tumor‐associated neovasculature of multiple solid tumor types including breast…”
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Dysfunctional TLR1 reduces the therapeutic efficacy of chemotherapy by attenuating HMGB1-mediated antitumor immunity in locally advanced colorectal cancer by Huang, Kevin Chih-Yang, Ke, Tao-Wei, Chen, Jia-Yi, Hong, Wei-Ze, Chiang, Shu-Fen, Lai, Chia-Ying, Chen, Tsung-Wei, Yang, Pei-Chen, Chen, Liang-Chi, Liang, Ji-An, Chen, William Tzu-Liang, Chao, K. S. Clifford

“…Regional lymph node metastasis is an important predictor for survival outcome and an indicator for postoperative adjuvant chemotherapy in patients with…”
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