Search Results - "Chao, Edward"
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SGLT2 inhibition — a novel strategy for diabetes treatment
Published in Nature reviews. Drug discovery (01-07-2010)“…Key Points Side effects of current type 2 diabetes mellitus (T2DM) medications, which include hypoglycaemia, weight gain, and nausea and vomiting, can hamper…”
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Zooming In, Then Out: Why We Must Apply Human-Centered Design to Transform Diabetes Technology
Published in Journal of diabetes science and technology (01-01-2024)“…Technological advances in devices, such as continuous glucose monitors (CGMs) or intermittently scanned continuous glucose monitors (isCGMs), do not…”
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SGLT-2 Inhibitors: A New Mechanism for Glycemic Control
Published in Clinical diabetes (01-01-2014)“…Glucosuria, the presence of glucose in the urine, has long been regarded as a consequence of uncontrolled diabetes. However, glucose excretion can be induced…”
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1078-P: Codesigning Diversity, Equity, and Inclusion Communication Tools for Diabetes Management
Published in Diabetes (New York, N.Y.) (20-06-2023)“…Only 29% of African-Americans and 39% of Latinx persons living with type 1 diabetes mellitus (T1DM) use insulin pumps, compared with 61% of white individuals…”
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983-P: GluClose—Collaboratively Designing a More Personalized Continuous Glucose Monitoring (CGM) Onboarding Experience
Published in Diabetes (New York, N.Y.) (20-06-2023)“…Current resources for acclimating patients to continuous glucose monitoring (CGM) may not be convenient or individualized. We examined if design thinking could…”
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Evaluation of TomoTherapy dose calculations with intrafractional motion and motion compensation
Published in Medical physics (Lancaster) (01-01-2018)“…Purpose Anatomical motion, both cyclical and aperiodic, can impact the dose delivered during external beam radiation. In this work, we evaluate the use of a…”
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AAPM Task Group Report 306: Quality control and assurance for tomotherapy: An update to Task Group Report 148
Published in Medical physics (Lancaster) (01-03-2023)“…Since the publication of AAPM Task Group (TG) 148 on quality assurance (QA) for helical tomotherapy, there have been many new developments on the tomotherapy…”
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Collaboratively Designing an App for a More Personalized, Community-Endorsed Continuous Glucose Monitoring Onboarding Experience: An Early Study
Published in Journal of diabetes science and technology (01-01-2024)“…Background: Acclimating to a new technology device, such as a continuous glucose monitor (CGM), can be challenging. Current resources may not sufficiently…”
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A smoothed corrected score approach for proportional hazards model with misclassified discretized covariates induced by error‐contaminated continuous time‐dependent exposure
Published in Biometrics (01-03-2023)“…We consider the proportional hazards model in which the covariates include the discretized categories of a continuous time‐dependent exposure variable measured…”
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Fast Statistical Iterative Reconstruction for Mega-voltage Computed Tomography
Published in The Journal of Medical Investigation (2020)“…Statistical iterative reconstruction is expected to improve the image quality of computed tomography (CT). However, one of the challenges of iterative…”
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Efficient Laplacian and Adaptive Gaussian Quadrature Algorithms for Multilevel Generalized Linear Mixed Models
Published in Journal of computational and graphical statistics (01-03-2006)“…Mixed-effects models have become a popular approach for the analysis of grouped data that arise in many areas as diverse as clinical trials, epidemiology, and…”
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A paradigm shift in diabetes therapy--dapagliflozin and other SGLT2 inhibitors
Published in Discovery medicine (01-03-2011)“…Blocking sodium-glucose cotransporters (SGLTs) to decrease the reabsorption of glucose--and thus increase renal glucose excretion--represents a novel…”
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Using 4D dose accumulation to calculate organ‐at‐risk dose deviations from motion‐synchronized liver and lung tomotherapy treatments
Published in Journal of applied clinical medical physics (01-07-2022)“…Tracking systems such as Radixact Synchrony change the planned delivery of radiation during treatment to follow the target. This is typically achieved without…”
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Diabetes: Dapagliflozin--redefining treatment of T2DM?
Published in Nature reviews. Endocrinology (01-12-2011)Get full text
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Dapagliflozin—redefining treatment of T2DM?
Published in Nature reviews. Endocrinology (01-12-2011)“…Glycemic control for many patients with type 2 diabetes mellitus (T2DM) is elusive, and the adverse effects of treatment, including hypoglycemia and weight…”
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Simulation Extrapolation Method for Cox Regression Model with a Mixture of Berkson and Classical Errors in the Covariates using Calibration Data
Published in The international journal of biostatistics (06-04-2019)“…Many biomedical or epidemiological studies often aim to assess the association between the time to an event of interest and some covariates under the Cox…”
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Influence of medical students' past experiences and innate dexterity on suturing performance
Published in The American journal of surgery (01-08-2014)“…Abstract Background Medical students often site their ability to excel at technical tasks as justification for choosing surgery as a career path. We sought to…”
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Open Abdomen Management in the Age of Damage Control Resuscitation
Published in Journal of the American College of Surgeons (01-10-2016)Get full text
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Dapagliflozin: an evidence-based review of its potential in the treatment of type-2 diabetes
Published in Core evidence (01-01-2012)“…Dapagliflozin is a sodium-glucose co-transporter-2 inhibitor that lowers plasma glucose by decreasing its renal reabsorption. The resulting excretion of…”
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A slit method to determine the focal spot size and shape of TomoTherapy system
Published in Medical physics (Lancaster) (01-06-2011)“…Purpose : To obtain accurate x-ray source profile measurements using a slit-collimator, the slit-collimator should have a narrow width, large height, and be…”
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