Search Results - "Chao, Alexander T."

Ligand-Bound Structures of the Dengue Virus Protease Reveal the Active Conformation by Noble, Christian G, Seh, Cheah Chen, Chao, Alexander T, Shi, Pei Yong

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis by Manjunatha, Ujjini H., Vinayak, Sumiti, Zambriski, Jennifer A., Chao, Alexander T., Sy, Tracy, Noble, Christian G., Bonamy, Ghislain M. C., Kondreddi, Ravinder R., Zou, Bin, Gedeck, Peter, Brooks, Carrie F., Herbert, Gillian T., Sateriale, Adam, Tandel, Jayesh, Noh, Susan, Lakshminarayana, Suresh B., Lim, Siau H., Goodman, Laura B., Bodenreider, Christophe, Feng, Gu, Zhang, Lijun, Blasco, Francesca, Wagner, Juergen, Leong, F. Joel, Striepen, Boris, Diagana, Thierry T.

“…Diarrhoeal disease is responsible for 8.6% of global child mortality. Recent epidemiological studies found the protozoan parasite Cryptosporidium to be a…”
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Design of potent antimalarials with generative chemistry by Godinez, William J., Ma, Eric J., Chao, Alexander T., Pei, Luying, Skewes-Cox, Peter, Canham, Stephen M., Jenkins, Jeremy L., Young, Joseph M., Martin, Eric J., Guiguemde, W. Armand

“…Recent advances in generative modelling allow designing novel compounds through deep neural networks. One such neural network model, JT-VAE (the Junction Tree…”
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Cryptosporidiosis Drug Discovery: Opportunities and Challenges by Manjunatha, Ujjini H, Chao, Alexander T, Leong, F. Joel, Diagana, Thierry T

“…The apicomplexan parasite Cryptosporidium is the second most important diarrheal pathogen causing life-threatening diarrhea in children, which is also…”
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Cryptosporidium PI(4)K inhibitor EDI048 is a gut-restricted parasiticidal agent to treat paediatric enteric cryptosporidiosis by Manjunatha, Ujjini H., Lakshminarayana, Suresh B., Jumani, Rajiv S., Chao, Alexander T., Young, Joseph M., Gable, Jonathan E., Knapp, Mark, Hanna, Imad, Galarneau, Jean-Rene, Cantwell, John, Kulkarni, Upendra, Turner, Michael, Lu, Peichao, Darrell, Kristen H., Watson, Lucy C., Chan, Katherine, Patra, Debjani, Mamo, Mulugeta, Luu, Catherine, Cuellar, Carlos, Shaul, Jacob, Xiao, Linda, Chen, Ying-Bo, Carney, Shannon K., Lakshman, Jay, Osborne, Colin S., Zambriski, Jennifer A., Aziz, Natasha, Sarko, Christopher, Diagana, Thierry T.

“…Diarrhoeal disease caused by Cryptosporidium is a major cause of morbidity and mortality in young and malnourished children from low- and middle-income…”
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Development of a Cytopathic Effect-Based Phenotypic Screening Assay against Cryptosporidium by Chao, Alexander T, Lee, Boon Heng, Wan, Kah Fei, Selva, Jeremy, Zou, Bin, Gedeck, Peter, Beer, David John, Diagana, Thierry T, Bonamy, Ghislain M. C, Manjunatha, Ujjini H

“…Cryptosporidiosis is a diarrheal disease predominantly caused by Cryptosporidium parvum (Cp) and Cryptosporidium hominis (Ch), apicomplexan parasites which…”
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A Cryptosporidium PI by Manjunatha, Ujjini H, Vinayak, Sumiti, Zambriski, Jennifer A, Chao, Alexander T, Sy, Tracy, Noble, Christian G, Bonamy, Ghislain M. C

“…Diarrhoeal disease is responsible for 8.6% of global child mortality. Recent epidemiological studies found the protozoan parasite Cryptosporidium to be a…”
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A Cryptosporidium PIK inhibitor is a drug candidate for cryptosporidiosis by Manjunatha, Ujjini H, Vinayak, Sumiti, Zambriski, Jennifer A, Chao, Alexander T, Sy, Tracy, Noble, Christian G, Bonamy, Ghislain M. C, Kondreddi, Ravinder R, Zou, Bin, Gedeck, Peter, Brooks, Carrie F, Herbert, Gillian T, Sateriale, Adam, Tandel, Jayesh, Noh, Susan, Lakshminarayana, Suresh B, Lim, Siau H, Goodman, Laura B, Bodenreider, Christophe, Feng, Gu, Zhang, Lijun, Blasco, Francesca, Wagner, Juergen, Leong, F. Joel, Striepen, Boris, Diagana, Thierry T

“…Diarrhoeal disease is responsible for 8.6% of global child mortality. Recent epidemiological studies found the protozoan parasite Cryptosporidium to be a…”
Get full text