Search Results - "Chantharaksri, Udom"
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Redox Reaction of Artemisinin with Ferrous and Ferric Ions in Aqueous Buffer
Published in Chemical & pharmaceutical bulletin (01-12-2001)“…Artemisinin, a sesquiterpene with endoperoxide bond, possesses potent antimalarial activity against the ring and late stage of chloroqine-resistant Plasmodium…”
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2
Improvement of vascular function by chronic administration of a cyclo-oxygenase inhibitor in cholesterol-fed rabbits
Published in Clinical and experimental pharmacology & physiology (01-05-2003)“…Summary 1. Atherosclerotic cardio‐ and cerebrovascular disease is a leading cause of mortality in Western countries. Aspirin‐like drugs are widely used to…”
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3
Effect of Artemisinin on Lipid Peroxidation and Fluidity of the Erythrocyte Membrane in Malaria
Published in Biological & pharmaceutical bulletin (01-11-2000)“…The effect of artemisinin on membrane fluidity of erythrocytes was investigated using spin labeling compounds, doxyl stearic acids. The membrane fluidity of…”
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4
Atorvastatin affects TLR4 clustering via lipid raft modulation
Published in International immunopharmacology (01-08-2010)“…Statins, HMG-CoA reductase inhibitors, are used widely in the treatment of hypercholesterolemia. Apart from lowering lipid levels, statins have been shown to…”
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5
Pharmacokinetics of Deferiprone in Patients with β-Thalassaemia: Impact of Splenectomy and Iron Status
Published in Clinical pharmacokinetics (2011)“…Background and Objective Iron-rich transfusions and/or a compensatory increase in iron absorption ultimately result in iron loading in patients with…”
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6
Vitamin E supplement improves erythrocyte membrane fluidity of thalassemia: an ESR spin labeling study
Published in Journal of the Medical Association of Thailand (01-01-2012)“…Beta-thalassemia/Hemoglobin E (beta-thal/Hb E) is prevalent in Thailand. The imbalance of globin chains in red blood cells is the primary cause of this anemic…”
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7
UGT1A6 genotype‐related pharmacokinetics of deferiprone (L1) in healthy volunteers
Published in British journal of clinical pharmacology (01-06-2008)“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • UGT1A6 has been proposed as the predominant isoform responsible for the glucuronidation of deferiprone. • UGT1A6*2…”
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8
Oxidative Modification and Poor Protective Activity of HDL on LDL Oxidation in Thalassemia
Published in Lipids (01-07-2010)“…Oxidative modification of low-density lipoprotein (LDL) has been reported in thalassemia, which is a consequence of oxidative stress. However, the levels of…”
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9
Pharmacokinetics of Deferiprone in Patients with [beta]-Thalassaemia
Published in Clinical pharmacokinetics (01-01-2011)“…Background and Objective: Iron-rich transfusions and/or a compensatory increase in iron absorption ultimately result in iron loading in patients with…”
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10
Lipid fluidity at different regions in LDL and HDL of β-thalassemia/Hb E patients
Published in Biochemical and biophysical research communications (24-11-2006)“…Atherosclerosis-related vascular complications in β-thalassemia/hemoglobin E (β-thal/Hb E) patients may result from iron induced oxidation of lipoproteins. To…”
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11
Modification of platelet shape change parameter by oxidized lipoprotein from beta-thalassemia/Hemoglobin E
Published in Journal of the Medical Association of Thailand (01-04-2009)“…Beta-thalassemia/Hemoglobin E (beta-thal/Hb E) is a congenital hemolytic anemia that is prevalent in Thailand Pulmonary arterial occlusion is the cause of…”
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12
Modification of platelet shape change parameter by modified phospholipids in oxidized LDL
Published in Journal of the Medical Association of Thailand (01-02-2009)“…It is believed that the oxidatively modified lipoproteins play a critical role in activating platelets and is a contributing factor in the etiology of a number…”
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13
The reduction of cholesteryl linoleate in lipoproteins: an index of clinical severity in beta-thalassemia/Hb E
Published in Clinical chemistry and laboratory medicine (01-05-2006)“…Oxidative modification of lipoproteins has been reported in beta-thalassemia and has been suggested to relate to atherogenesis-risk. This study focused on the…”
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14
Association between promoter and coding region mutations of UDP-glucuronosyltransferase 1A1 and β-thalassemia/Hb E with cholelithiasis
Published in European journal of haematology (01-04-2008)“…Background and objectives: Cholelithiasis has been observed with high incidence in beta‐thalassemia/hemoglobin E (β‐thal/Hb E). Recent studies have shown that…”
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15
Pharmaco/ferrokinetic-related pro-oxidant activity of deferiprone in beta-thalassemia
Published in Free radical research (2009)“…The potential of free radical formation in serum of beta-thalassemia/Hb E patients receiving a single oral dose of 25 mg/kg body weight of deferiprone, a…”
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16
Effects of combined UDP-glucuronosyltransferase (UGT) 1A128 and 1A62 on paracetamol pharmacokinetics in beta-thalassemia/HbE
Published in Pharmacology (01-01-2007)“…In addition to pathophysiological changes, genetic variations can alter drug pharmacokinetics in patients with thalassemia. Numerous drugs are metabolized by…”
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17
Paraoxonase and platelet-activating factor acetylhydrolase activities in lipoproteins of beta-thalassemia/hemoglobin E patients
Published in Clinical chemistry and laboratory medicine (01-01-2007)“…Iron-induced oxidative stress may be implicated in the alteration of the lipoprotein-associated antioxidant enzymes paraoxonase 1 (PON1) and…”
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18
Lipid fluidity at different regions in LDL and HDL of {beta}-thalassemia/Hb E patients
Published in Biochemical and biophysical research communications (24-11-2006)“…Atherosclerosis-related vascular complications in {beta}-thalassemia/hemoglobin E ({beta}-thal/Hb E) patients may result from iron induced oxidation of…”
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19
Hemin: a possible cause of oxidative stress in blood circulation of beta-thalassemia/hemoglobin E disease
Published in Free radical research (01-01-2003)“…A correlation between endogenous hemin and pro-oxidant activity was revealed in serum of beta-thalassemia/hemoglobin E disease (beta-thal/Hb E), which is the…”
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20
The effects of vitamin E on platelet activity in β‐thalassaemia patients
Published in British journal of haematology (01-11-2003)“…A double‐blind, crossover, placebo‐controlled study of the effect of vitamin E on platelet functions was performed on nine splenectomized and 16…”
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