Search Results - "Chanond A. Nasamran"

Identification of adipose tissue transcriptomic memory of anorexia nervosa by Zapata, Rizaldy C., Nasamran, Chanond A., Chilin-Fuentes, Daisy R., Dulawa, Stephanie C., Osborn, Olivia

“…BACKGROUNDAnorexia nervosa (AN) is a complex debilitating disease characterized by intense fear of weight gain and excessive exercise. It is the deadliest of…”
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The genomic landscape of Ménière's disease: a path to endolymphatic hydrops by Fisch, Kathleen M, Rosenthal, Sara Brin, Mark, Adam, Sasik, Roman, Nasamran, Chanond A, Clifford, Royce, Derebery, M Jennifer, Boussaty, Ely, Jepsen, Kristen, Harris, Jeffrey, Friedman, Rick A

“…Ménière's disease (MD) is a disorder of the inner ear that causes episodic bouts of severe dizziness, roaring tinnitus, and fluctuating hearing loss. To date,…”
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Single-Cell Transcriptomes Reveal a Complex Cellular Landscape in the Middle Ear and Differential Capacities for Acute Response to Infection by Ryan, Allen F, Nasamran, Chanond A, Pak, Kwang, Draf, Clara, Fisch, Kathleen M, Webster, Nicholas, Kurabi, Arwa

“…Single-cell transcriptomics was used to profile cells of the normal murine middle ear. Clustering analysis of 6770 transcriptomes identified 17 cell clusters…”
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Transcriptional Time Course After Rotator Cuff Tear by Vasquez-Bolanos, Laura S., Gibbons, Michael C., Ruoss, Severin, Wu, Isabella T., Vargas-Vila, Mario, Hyman, Sydnee A., Esparza, Mary C., Fithian, Donald C., Lane, John G., Singh, Anshuman, Nasamran, Chanond A., Fisch, Kathleen M., Ward, Samuel R.

“…Rotator cuff (RC) tears are prevalent in the population above the age of 60. The disease progression leads to muscle atrophy, fibrosis, and fatty infiltration…”
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Targeting Clic1 for the treatment of obesity: A novel therapeutic strategy to reduce food intake and body weight by Zapata, Rizaldy C., Zhang, Dinghong, Yoon, Dongmin, Nasamran, Chanond A., Chilin-Fuentes, Daisy R., Libster, Avraham, Chaudry, Besma S., Lopez-Valencia, Mariela, Ponnalagu, Devasena, Singh, Harpreet, Petrascheck, Michael, Osborn, Olivia

“…Despite great advances in obesity therapeutics in recent years, there is still a need to identify additional therapeutic targets for the treatment of this…”
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Spatial transcriptomics tools allow for regional exploration of heterogeneous muscle pathology in the pre-clinical rabbit model of rotator cuff tear by Ruoss, Severin, Esparza, Mary C, Vasquez-Bolanos, Laura S, Nasamran, Chanond A, Fisch, Kathleen M, Engler, Adam J, Ward, Samuel R

“…Background Conditions affecting skeletal muscle, such as chronic rotator cuff tears, low back pain, dystrophies, and many others, often share changes in muscle…”
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Transcriptional time course after rotator cuff repair in 6 month old female rabbits by Vasquez-Bolanos, Laura S, Gibbons, Michael C, Ruoss, Severin, Wu, Isabella T, Esparza, Mary C, Fithian, Donald C, Lane, John G, Singh, Anshuman, Nasamran, Chanond A, Fisch, Kathleen M, Ward, Samuel R

“…Rotator cuff tears are prevalent in the population above the age of 60. The disease progression leads to muscle atrophy, fibrosis, and fatty infiltration,…”
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Distributed Intrinsic Functional Connectivity Patterns Predict Diagnostic Status in Large Autism Cohort by Jahedi, Afrooz, Nasamran, Chanond A, Faires, Brian, Fan, Juanjuan, Müller, Ralph-Axel

“…Diagnosis of autism spectrum disorder (ASD) currently relies on behavioral observations because brain markers are unknown. Machine learning approaches can…”
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Corrigendum: Transcriptional Time Course After Rotator Cuff Tear by Vasquez-Bolanos, Laura S., Gibbons, Michael C., Ruoss, Severin, Wu, Isabella T., Vargas-Vila, Mario, Hyman, Sydnee A., Esparza, Mary C., Fithian, Donald C., Lane, John G., Singh, Anshuman, Nasamran, Chanond A., Fisch, Kathleen M., Ward, Samuel R.

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ANT2 drives proinflammatory macrophage activation in obesity by Moon, Jae-Su, da Cunha, Flavia Franco, Huh, Jin Young, Andreyev, Alexander Yu, Lee, Jihyung, Mahata, Sushil K, Reis, Felipe Cg, Nasamran, Chanond A, Lee, Yun Sok

“…Macrophage proinflammatory activation is an important etiologic component of the development of insulin resistance and metabolic dysfunction in obesity…”
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Differential blood DNA methylation across Lewy body dementias by Nasamran, Chanond A., Sachan, Anubhav Nikunj Singh, Mott, Jennifer, Kuras, Yuliya I., Scherzer, Clemens R., Study, Harvard Biomarkers, Ricciardelli, Eugenia, Jepsen, Kristen, Edland, Steven D., Fisch, Kathleen M., Desplats, Paula

“…Introduction Dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD) are characterized by cognitive alterations, visual hallucinations, and…”
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Maladaptive lymphangiogenesis is associated with synovial iron accumulation and delayed clearance in factor VIII-deficient mice after induced hemarthrosis by Cooke, Esther J, Joseph, Bilgimol C, Nasamran, Chanond A, Fisch, Kathleen M, von Drygalski, Annette

“…Mechanisms of iron clearance from hemophilic joints are unknown. To better understand mechanisms of iron clearance following joint bleeding in a mouse model of…”
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Are there sex‐dependent transcriptional differences in human subacromial bursa from traumatic versus degenerative rotator cuff tears? by Ruoss, Severin, Nasamran, Chanond A., Singh, Anshuman, Lane, John G., Ward, Samuel R.

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Defining the relationship of salivary gland malignancies to novel cell subpopulations in human salivary glands using single nucleus RNA‐sequencing by Nakagawa, Takuya, Santos, Jessica, Nasamran, Chanond A., Sen, Prakriti, Sadat, Sayed, Monther, Abdula, Bendik, Joseph, Ebisumoto, Koji, Hu, Jingjing, Preissl, Sebastian, Guo, Theresa, Vavinskaya, Vera, Fisch, Kathleen M., Califano, Joseph A.

“…Salivary glands have essential roles in maintaining oral health, mastication, taste and speech, by secreting saliva. Salivary glands are composed of several…”
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HIF-2α drives hepatic Kupffer cell death and proinflammatory recruited macrophage activation in nonalcoholic steatohepatitis by Jeelani, Ishtiaq, Moon, Jae-Su, da Cunha, Flavia Franco, Nasamran, Chanond A, Jeon, Seokhyun, Zhang, Xinhang, Bandyopadhyay, Gautam K, Dobaczewska, Katarzyna, Mikulski, Zbigniew, Hosseini, Mojgan, Liu, Xiao, Kisseleva, Tatiana, Brenner, David A, Singh, Seema, Loomba, Rohit, Kim, Minkyu, Lee, Yun Sok

“…Proinflammatory hepatic macrophage activation plays a key role in the development of nonalcoholic steatohepatitis (NASH). This involves increased embryonic…”
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The Lung Microenvironment Instructs Gene Transcription in Neonatal and Adult Alveolar Macrophages by Honda, Asami, Hoeksema, Marten A, Sakai, Mashito, Lund, Sean J, Lakhdari, Omar, Butcher, Lindsay D, Rambaldo, Tara C, Sekiya, Neal M, Nasamran, Chanond A, Fisch, Kathleen M, Sajti, Eniko, Glass, Christopher K, Prince, Lawrence S

“…Immaturity of alveolar macrophages (AMs) around birth contributes to the susceptibility of newborns to lung disease. However, the molecular features…”
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High placental expression of FLT1, LEP, PHYHIP and IL3RA – In persons of African ancestry with severe preeclampsia by Aisagbonhi, Omonigho, Bui, Tony, Nasamran, Chanond A., St. Louis, Hailee, Pizzo, Donald, Meads, Morgan, Mulholland, Megan, Magallanes, Celestine, Lamale-Smith, Leah, Laurent, Louise C., Morey, Robert, Jacobs, Marni B., Fisch, Kathleen M., Horii, Mariko

“…Mortality from preeclampsia (PE) and PE-associated morbidities are 3-to 5-fold higher in persons of African ancestry than in those of Asian and European…”
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Strategies to Identify Mesenchymal Stromal Cells in Minimally Manipulated Human Bone Marrow Aspirate Concentrate Lack Consensus by Ruoss, Severin, Walker, J. Todd, Nasamran, Chanond A., Fisch, Kathleen M., Paez, Conner J., Parekh, Jesal N., Ball, Scott T., Chen, Jeffrey L., Ahmed, Sonya S., Ward, Samuel R.

“…Background: There is a need to identify and quantify mesenchymal stromal cells (MSCs) in human bone marrow aspirate concentrate (BMAC) source tissues, but…”
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Mechanisms of vascular permeability and remodeling associated with hemarthrosis in factor VIII‐deficient mice by Cooke, Esther J., Wyseure, Tine, Zhou, Jenny Y., Gopal, Srila, Nasamran, Chanond A., Fisch, Kathleen M., Manon‐Jensen, Tina, Karsdal, Morten A., Mosnier, Laurent O., Drygalski, Annette

“…Background Vascular remodeling associated with hemophilic arthropathy (HA) may contribute to bleed propagation, but the mechanisms remain poorly understood…”
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Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h by Espanola, Sophia G., Song, Hyemin, Ryu, Eunjin, Saxena, Aditya, Kim, Eun-Sun, Manegold, Jennifer E., Nasamran, Chanond A., Sahoo, Debashis, Oh, Chang-Kyu, Bickers, Cara, Shin, Unbeom, Grainger, Stephanie, Park, Yong Hwan, Pandolfo, Lauren, Kang, Mi-Sun, Kang, Sukhyun, Myung, Kyungjae, Cooper, Kimberly L., Yelon, Deborah, Traver, David, Lee, Yoonsung

“…Haematopoietic stem and progenitor cells (HSPCs) have been the focus of developmental and regenerative studies, yet our understanding of the signalling events…”
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