Search Results - "Channer, K. S."

Androgens, insulin resistance and vascular disease in men by Kapoor, D., Malkin, C. J., Channer, K. S., Jones, T. H.

“…Summary Type 2 diabetes mellitus is increasing globally and is an established risk factor for the development of atherosclerotic vascular disease. Insulin…”
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Testosterone replacement in hypogonadal men with angina improves ischaemic threshold and quality of life by Malkin, C J, Pugh, P J, Morris, P D, Kerry, K E, Jones, R D, Jones, T H, Channer, K S

“…Background: Low serum testosterone is associated with several cardiovascular risk factors including dyslipidaemia, adverse clotting profiles, obesity, and…”
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Testosterone treatment for men with chronic heart failure by Pugh, P J, Jones, R D, West, J N, Jones, T H, Channer, K S

“…[...]testosterone has been shown to augment cardiac output acutely in men with CHF. 1, 2 Low plasma concentrations of testosterone have been described in men…”
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Androgen receptor CAG repeat polymorphism is associated with serum testosterone levels, obesity and serum leptin in men with type 2 diabetes by Stanworth, R D, Kapoor, D, Channer, K S, Jones, T H

“…ObjectiveTo determine the relationships between androgen receptor CAG repeat polymorphism length (AR CAG), sex hormones and clinical variables in men with type…”
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A randomised controlled trial of warfarin versus aspirin for stroke prevention in octogenarians with atrial fibrillation (WASPO) by Rash, Amar, Downes, Tom, Portner, Robin, Yeo, Wilf W., Morgan, Nicolette, Channer, Kevin S.

“…Background: atrial fibrillation (AF) is the commonest chronic arrhythmia with a prevalence of 9% in octogenarians and accounts for 24% of the stroke risk in…”
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Dyslipidaemia is associated with testosterone, oestradiol and androgen receptor CAG repeat polymorphism in men with type 2 diabetes by Stanworth, R. D., Kapoor, D., Channer, K. S., Jones, T. H.

“…Summary Objective  There is a high prevalence of low testosterone and dyslipidaemia in men with type 2 diabetes. The androgen receptor CAG repeat polymorphism…”
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Selective Inhibition of L-Type Ca2+ Channels in A7r5 Cells by Physiological Levels of Testosterone by Hall, J, Jones, R. D, Jones, T. H, Channer, K. S, Peers, C

“…Testosterone has marked beneficial cardiovascular effects, many of which have been attributed to a vasodilatory action. However, the molecular target of…”
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The role of androgen receptor CAG repeat polymorphism and other factors which affect the clinical response to testosterone replacement in metabolic syndrome and type 2 diabetes: TIMES2 sub-study by Stanworth, R D, Akhtar, S, Channer, K S, Jones, T H

“…ContextThe TIMES2 (testosterone replacement in hypogonadal men with either metabolic syndrome or type 2 diabetes) study reported beneficial effects of…”
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Chronic atrial fibrillation: a systematic review of medical heart rate control management by Nikolaidou, T, Channer, K S

“…Objective:Recent guidelines by the National Institute for Health and Clinical Excellence (NICE) and the American College of Cardiology/American Heart…”
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Testosterone as a protective factor against atherosclerosis--immunomodulation and influence upon plaque development and stability by Malkin, CJ, Pugh, PJ, Jones, RD, Jones, TH, Channer, KS

“…Inflammation plays a central pathogenic role in the initiation and progression of coronary atheroma and its clinical consequences. Cytokines are the mediators…”
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Novel platelet membrane glycoprotein VI dimorphism is a risk factor for myocardial infarction by CROFT, S. A, SAMANI, N. J, TEARE, M. D, HAMPTON, K. K, STEEDS, R. P, CHANNER, K. S, DALY, M. E

“…Glycoprotein (GP) VI plays a crucial role in platelet activation and aggregation. We investigated whether polymorphic variation at the GP VI locus confers an…”
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The triad of erectile dysfunction, hypogonadism and the metabolic syndrome by Shabsigh, R, Arver, S, Channer, K S, Eardley, I, Fabbri, A, Gooren, L, Heufelder, A, Jones, H, Meryn, S, Zitzmann, M

“…To identify the relationship of erectile dysfunction, hypogonadism and the metabolic syndrome in the context of men's health. An Expert Panel Meeting was held…”
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Men with coronary artery disease have lower levels of androgens than men with normal coronary angiograms by English, K.M, Mandour, O, Steeds, R.P, Diver, M.J, Jones, T.H, Channer, K.S

“…Aims High androgen levels are presumed by many to explain the male predisposition to coronary artery disease. However, natural androgens inhibit male…”
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Erectile dysfunction is associated with low bioactive testosterone levels and visceral adiposity in men with type 2 diabetes by Kapoor, D., Clarke, S., Channer, K. S., Jones, T. H.

“…Summary Low testosterone levels in men are associated with type 2 diabetes mellitus. Erectile dysfunction (ED) is a frequent complication of type 2 diabetes…”
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Testosterone acts as a coronary vasodilator by a calcium antagonistic action by ENGLISH, K. M, JONES, R. D, JONES, T. H, MORICE, A. H, CHANNER, K. S

“…T acts as a vasodilator in vitro and in vivo. Supplemental T therapy in humans with angina improves symptoms and reduces objective measures of ischemia. In…”
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Testosterone replacement therapy improves insulin resistance, glycaemic control, visceral adiposity and hypercholesterolaemia in hypogonadal men with type 2 diabetes by Kapoor, D, Goodwin, E, Channer, K S, Jones, T H

“…Objective: Low levels of testosterone in men have been shown to be associated with type 2 diabetes, visceral adiposity, dyslipidaemia and metabolic syndrome…”
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Gender differences in the vasomotor effects of different steroid hormones in rat pulmonary and coronary arteries by English, K M, Jones, R D, Jones, T H, Morice, A H, Channer, K S

“…It is well recognised that oestrogens possess vasodilatory properties, and similar responses to testosterone have been demonstrated. However, vasomotor effects…”
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Sexual health as a portal to men's health: a problem turned around into an opportunity by Shabsigh, R, Arver, S, Channer, K S, Eardley, I, Fabbri, A, Gooren, L, Heufelder, A, Jones, H, Meryn, S, Zitzmann, M

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The effect of testosterone replacement therapy on adipocytokines and C-reactive protein in hypogonadal men with type 2 diabetes by Kapoor, D, Clarke, S, Stanworth, R, Channer, K S, Jones, T H

“…Objective: Serum testosterone levels are known to inversely correlate with insulin sensitivity and obesity in men. Furthermore, there is evidence to suggest…”
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Effect of treatment of carotid artery stenosis on blood pressure: a comparison of hemodynamic disturbances after carotid endarterectomy and endovascular treatment by McKevitt, F M, Sivaguru, A, Venables, G S, Cleveland, T J, Gaines, P A, Beard, J D, Channer, K S

“…Carotid intervention by carotid endarterectomy (CEA) or endovascular treatment may cause hemodynamic change. The immediate and long-term effects on blood…”
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