Search Results - "Channanath, Arshad"

Investigating the Role of Myeloperoxidase and Angiopoietin-like Protein 6 in Obesity and Diabetes by Qaddoumi, Mohammad G., Alanbaei, Muath, Hammad, Maha M., Al Khairi, Irina, Cherian, Preethi, Channanath, Arshad, Thanaraj, Thangavel Alphonse, Al-Mulla, Fahd, Abu-Farha, Mohamed, Abubaker, Jehad

“…Myeloperoxidase (MPO) is positively associated with obesity and diet-induced insulin resistance. Angiopoietin-like protein 6 (ANGPTL6) regulates metabolic…”
Get full text

SARS-CoV-2: Possible recombination and emergence of potentially more virulent strains by Haddad, Dania, John, Sumi Elsa, Mohammad, Anwar, Hammad, Maha M, Hebbar, Prashantha, Channanath, Arshad, Nizam, Rasheeba, Al-Qabandi, Sarah, Al Madhoun, Ashraf, Alshukry, Abdullah, Ali, Hamad, Thanaraj, Thangavel Alphonse, Al-Mulla, Fahd

“…COVID-19 is challenging healthcare preparedness, world economies, and livelihoods. The infection and death rates associated with this pandemic are strikingly…”
Get full text

Frequency of functional exonic single-nucleotide polymorphisms and haplotype distribution in the SLCO1B1 gene across genetic ancestry groups in the Qatari population by Dashti, Mohammed, Al-Matrouk, Abdullah, Channanath, Arshad, Al-Mulla, Fahd, Thanaraj, Thangavel Alphonse

“…Organic anion transporting polypeptides (OATP), which are encoded by SLCO genes, participate in the hepatic elimination of drugs and xenobiotics. SLCO1B1 is an…”
Get full text

Genome-wide landscape establishes novel association signals for metabolic traits in the Arab population by Hebbar, Prashantha, Abubaker, Jehad Ahmed, Abu-Farha, Mohamed, Alsmadi, Osama, Elkum, Naser, Alkayal, Fadi, John, Sumi Elsa, Channanath, Arshad, Iqbal, Rasheeba, Pitkaniemi, Janne, Tuomilehto, Jaakko, Sladek, Robert, Al-Mulla, Fahd, Thanaraj, Thangavel Alphonse

“…While the Arabian population has a high prevalence of metabolic disorders, it has not been included in global studies that identify genetic risk loci for…”
Get full text

Ethnic differences in association of high body mass index with early onset of Type 1 diabetes - Arab ethnicity as case study by Channanath, Arshad M, Elkum, Naser, Al-Abdulrazzaq, Dalia, Tuomilehto, Jaakko, Shaltout, Azza, Thanaraj, Thangavel Alphonse

“…The "accelerator hypothesis" predicts early onset of Type 1 diabetes (T1D) in heavier children. Studies testing direction of correlation between body mass…”
Get full text

1270-P: ICA1 Is Differentially Methylated and Expressed in Familial Type 1 Diabetes by DASHTI, MOHAMMED H., NIZAM, RASHEEBA, HEBBAR, PRASHANTHA, JACOB, SINDHU, JOHN, SUMI E., CHANNANATH, ARSHAD M., ALKANDARI, HESSA, THANGAVEL, ALPHONSE T., ALMULLA, FAHD

“…There has recently been a growing interest in examining the role of epigenetic modifications, such as DNA methylation, in the etiology of type 1 diabetes (T1D)…”
Get full text

Linkage analysis using whole exome sequencing data implicates SLC17A1, SLC17A3, TATDN2 and TMEM131L in type 1 diabetes in Kuwaiti families by Hebbar, Prashantha, Nizam, Rasheeba, John, Sumi Elsa, Antony, Dinu, Dashti, Mohammad, Channanath, Arshad, Shaltout, Azza, Al-Khandari, Hessa, Koistinen, Heikki A., Tuomilehto, Jaakko, Alsmadi, Osama, Thanaraj, Thangavel Alphonse, Al-Mulla, Fahd

“…Type 1 diabetes (T1D) is characterized by the progressive destruction of pancreatic β-cells, leading to insulin deficiency and lifelong dependency on exogenous…”
Get full text

Differentially methylated and expressed genes in familial type 1 diabetes by Dashti, Mohammed, Nizam, Rasheeba, Hebbar, Prashantha, Jacob, Sindhu, John, Sumi Elsa, Channanath, Arshad, Al-Kandari, Hessa, Thanaraj, Thangavel Alphonse, Al-Mulla, Fahd

“…There has recently been a growing interest in examining the role of epigenetic modifications, such as DNA methylation, in the etiology of type 1 diabetes…”
Get full text

Increased LRG1 Levels in Overweight and Obese Adolescents and Its Association with Obesity Markers, Including Leptin, Chemerin, and High Sensitivity C-Reactive Protein by Alhammad, Rashed, Abu-Farha, Mohamed, Hammad, Maha M, Thanaraj, Thangavel Alphonse, Channanath, Arshad, Alam-Eldin, Nada, Al-Sabah, Reem, Shaban, Lemia, Alduraywish, Abdulrahman, Al-Mulla, Fahd, Rahman, Abdur, Abubaker, Jehad

“…Leucine-rich α-2 glycoprotein1 (LRG1) is a member of the leucine-rich repeat (LRR) family that is implicated in multiple diseases, including cancer, aging, and…”
Get full text

ONECUT1 variants beyond type 1 and type 2 diabetes: exploring clinical diversity and epigenetic associations in Arab cohorts by Dashti, Mohammed, Nizam, Rasheeba, John, Sumi Elsa, Melhem, Motasem, Channanath, Arshad, Alkandari, Hessa, Thanaraj, Thangavel Alphonse, Al-Mulla, Fahd

“…gene, encoding hepatocyte nuclear factor 6, is involved in pancreas and liver development. mutations impair the function of pancreatic β-cells and control a…”
Get full text

Adolescent obesity and ANGPTL8: correlations with high sensitivity C-reactive protein, leptin, and chemerin by Hammad, Maha M, Channanath, Arshad M, Abu-Farha, Mohamed, Rahman, Abdur, Al Khairi, Irina, Cherian, Preethi, Alramah, Tahani, Alam-Eldin, Nada, Al-Mulla, Fahd, Thanaraj, Thangavel Alphonse, Abubaker, Jehad

“…Angiopoietin-like proteins (ANGPTLs) mediate many metabolic functions. We had recently reported increased plasma levels of ANGPTL8 in obese adults of Arab…”
Get full text

Use of Non-invasive Parameters and Machine-Learning Algorithms for Predicting Future Risk of Type 2 Diabetes: A Retrospective Cohort Study of Health Data From Kuwait by Farran, Bassam, AlWotayan, Rihab, Alkandari, Hessa, Al-Abdulrazzaq, Dalia, Channanath, Arshad, Thanaraj, Thangavel Alphonse

“…Objective: In recent decades, the Arab population has experienced an increase in the prevalence of type 2 diabetes (T2DM), particularly within the Gulf…”
Get full text

Distribution of HLA-B Alleles and Haplotypes in Qatari: Recommendation for Establishing Pharmacogenomic Markers Screening for Drug Hypersensitivity by Dashti, Mohammed, Al-Matrouk, Abdullah, Channanath, Arshad, Hebbar, Prashantha, Al-Mulla, Fahd, Thanaraj, Thangavel Alphonse

“…Human leukocyte antigen (HLA) proteins are present at the cellular surface of antigen-presenting cells and play a crucial role in the adaptive immune response…”
Get full text

268-LB: Investigating the Role of MPO and ANGPTL6 in Obesity and Diabetes and Their Potential Role in Wound Healing by QADDOUMI, MOHAMMAD G., ABU-FARHA, MOHAMED, THOMAS CHERIAN, PREETHI, AL KHAIRI, IRINA, MOHAMED CHANNANATH, ARSHAD, ALANBAEI, MUATH, ABUBAKER, JEHAD, AL-MULLA, FAHD

“…Purpose: Myeloperoxidase (MPO) is a major neutrophil-derived protein known to play an important role in inflammation, oxidative stress, and atherosclerosis…”
Get full text

Genome-wide association study identifies novel risk variants from RPS6KA1, CADPS, VARS, and DHX58 for fasting plasma glucose in Arab population by Hebbar, Prashantha, Abu-Farha, Mohamed, Alkayal, Fadi, Nizam, Rasheeba, Elkum, Naser, Melhem, Motasem, John, Sumi Elsa, Channanath, Arshad, Abubaker, Jehad, Bennakhi, Abdullah, Al-Ozairi, Ebaa, Tuomilehto, Jaakko, Pitkaniemi, Janne, Alsmadi, Osama, Al-Mulla, Fahd, Thanaraj, Thangavel Alphonse

“…Consanguineous populations of the Arabian Peninsula, which has seen an uncontrolled rise in type 2 diabetes incidence, are underrepresented in global studies…”
Get full text

LRG1 Associates with Iron Deficiency Anemia Markers in Adolescents by Alhammad, Rashed, Abu-Farha, Mohamed, Rahman, Abdur, Thanaraj, Thangavel Alphonse, Shaban, Lemia, Alsabah, Reem, Hamad, Samar, Hammad, Maha M, Channanath, Arshad, Al-Mulla, Fahd, Abubaker, Jehad

“…Leucine-rich α-2 glycoprotein1 (LRG1) has been shown to be associated with several health conditions; however, its association with iron deficiency anemia,…”
Get full text

Single nucleotide polymorphisms in vitamin D binding protein and 25-hydroxylase genes affect vitamin D levels in adolescents of Arab ethnicity in Kuwait by Rahman, Abdur, Abu-Farha, Mohamed, Channanath, Arshad, Hammad, Maha M., Anoop, Emil, Chandy, Betty, Melhem, Motasem, Al-Mulla, Fahd, Thanaraj, Thangavel Alphonse, Abubaker, Jehad

“…Vitamin D deficiency (VDD) is widespread in the Arab world despite ample sunshine throughout the year. In our previous study, lifestyle and socio-demographic…”
Get full text

The miR-668 binding site variant rs1046322 on WFS1 is associated with obesity in Southeast Asians by Hammad, Maha M., Abu-Farha, Mohamed, Hebbar, Prashantha, Anoop, Emil, Chandy, Betty, Melhem, Motasem, Channanath, Arshad, Al-Mulla, Fahd, Thanaraj, Thangavel Alphonse, Abubaker, Jehad

“…The Wolfram syndrome 1 gene ( WFS1) is the main causative locus for Wolfram syndrome, an inherited condition characterized by childhood-onset diabetes…”
Get full text

Effect of pioglitazone on inflammatory response and clinical outcome in T2DM patients with COVID-19: a randomized multicenter double-blind clinical trial by Baagar, Khaled, Alessa, Thamer, Abu-Farha, Mohamed, Abubaker, Jehad, Alhumaidi, Heba, Franco Ceruto, Jose Antonio, Hamad, Mohammad Khair, Omrani, Ali, Abdelrahman, Salma, Zaka-Ul Haq, Muhammad, Safi, Abdul Wajid, Alhariri, Bassem, Barman, Manish, Abdelmajid, Alaaeldin, Cancio, Humberto Vidal Denis, Elmekaty, Eman, Al-Khairi, Irina, Cherian, Preethi, Jayyousi, Lina, Ahmed, Mohammed, Qaddoumi, Mohammed, Hajji, Sulaiman, Esmaeel, Ahmad, Al-Andaleeb, Ali, Channanath, Arshad, Devarajan, Sriraman, Ali, Hamad, Thanaraj, Thangavel Alphonse, Al-Sabah, Salman, Al-Mulla, Fahd, Abdul-Ghani, Muhammad, Jayyousi, Amin

“…Coronavirus disease 2019 (COVID-19) caused by the coronavirus SARS-CoV-2, has emerged as a rapidly spreading contagious disease across the globe. Recent…”
Get full text

The Status of Metabolic Control in Patients With Type 2 Diabetes Attending Dasman Diabetes Institute, Kuwait by Qaddoumi, Mohammad, Al-Khamis, Yousuf, Channanath, Arshad, Tuomilehto, Jaakko, Badawi, Dalia

“…To evaluate metabolic control in patients with type 2 diabetes at Dasman Diabetes Institute (DDI, Kuwait), a specialist diabetes clinic and research center,…”
Get full text