Search Results - "Changou, Chun"

Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression by Shih, Jing-Wen, Chiang, Wei-Fan, Wu, Alexander T. H., Wu, Ming-Heng, Wang, Ling-Yu, Yu, Yen-Ling, Hung, Yu-Wen, Wang, Wen-Chang, Chu, Cheng-Ying, Hung, Chiu-Lien, Changou, Chun A., Yen, Yun, Kung, Hsing-Jien

“…Long noncoding RNAs (lncRNAs) have been implicated in hypoxia/HIF-1-associated cancer progression through largely unknown mechanisms. Here we identify MIR31HG…”
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Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear DNA leakage, and chromatin autophagy by Changou, Chun A., Chen, Yun-Ru, Xing, Li, Yen, Yun, Chuang, Frank Y. S., Cheng, R. Holland, Bold, Richard J., Ann, David K., Kung, Hsing-Jien

“…Significance Nutritional starvation therapy is under intensive investigation because it provides a potentially lower toxicity with higher specificity than…”
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Characterization of FN1–FGFR1 and novel FN1–FGF1 fusion genes in a large series of phosphaturic mesenchymal tumors by Lee, Jen-Chieh, Su, Sheng-Yao, Changou, Chun A, Yang, Rong-Sen, Tsai, Keh-Sung, Collins, Michael T, Orwoll, Eric S, Lin, Chung-Yen, Chen, Shu-Hwa, Shih, Shyang-Rong, Lee, Cheng-Han, Oda, Yoshinao, Billings, Steven D, Li, Chien-Feng, Nielsen, G Petur, Konishi, Eiichi, Petersson, Fredrik, Carpenter, Thomas O, Sittampalam, Kesavan, Huang, Hsuan-Ying, Folpe, Andrew L

“…Phosphaturic mesenchymal tumors typically cause paraneoplastic osteomalacia, chiefly as a result of FGF23 secretion. In a prior study, we identified FN1–FGFR1…”
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Hepatitis C Virus Non-Structural Protein 5A (NS5A) Disrupts Mitochondrial Dynamics and Induces Mitophagy by Jassey, Alagie, Liu, Ching-Hsuan, Changou, Chun A, Richardson, Christopher D, Hsu, Hsue-Yin, Lin, Liang-Tzung

“…Mitophagy is a selective form of autophagy, targeting damaged mitochondria for lysosomal degradation. Although HCV infection has been shown to induce…”
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CCL5 promotion of bioenergy metabolism is crucial for hippocampal synapse complex and memory formation by Ajoy, Reni, Lo, Yu-Chun, Ho, Man-Hau, Chen, You-Yin, Wang, Yun, Chen, Yuan-Hao, Jing-Yuan, Chiu, Changou, Chun Austin, Hsiung, Yuan-Chin, Chen, Hui-Min, Chang, Tzu-Hao, Lee, Cheng-Yang, Chiang, Yung-Hsiao, Chang, Wen-Chang, Hoffer, Barry, Chou, Szu-Yi

“…Glucoregulatory efficiency and ATP production are key regulators for neuronal plasticity and memory formation. Besides its chemotactic and neuroinflammatory…”
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A Phase II Clinical Trial on the Combination Therapy of PHY906 Plus Capecitabine in Hepatocellular Carcinoma by Changou, Chun A., Shiah, Her‐Shyong, Chen, Li‐Tzong, Liu, Servina, Luh, Frank, Liu, Shwu‐Huey, Cheng, Yung‐Chi, Yen, Yun

“…Lessons Learned A PHY906 and capecitabine combination could be effective as a salvage therapy for patients with hepatocellular carcinoma (HCC) previously…”
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Thyroxine inhibits resveratrol-caused apoptosis by PD-L1 in ovarian cancer cells by Chin, Yu-Tang, Wei, Po-Li, Ho, Yih, Nana, André Wendindondé, Changou, Chun A, Chen, Yi-Ru, Yang, Yu-Chen SH, Hsieh, Meng-Ti, Hercbergs, Aleck, Davis, Paul J, Shih, Ya-Jung, Lin, Hung-Yun

“…Thyroid hormone, l-thyroxine (T4), has been shown to promote ovarian cancer cell proliferation via a receptor on plasma membrane integrin αvβ3 and to induce…”
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Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism by Lee, Tzu-Yin, Lu, Wan-Jung, Changou, Chun A., Hsiung, Yuan-Chin, Trang, Nguyen T. T., Lee, Cheng-Yang, Chang, Tzu-Hao, Jayakumar, Thanasekaran, Hsieh, Cheng-Ying, Yang, Chih-Hao, Chang, Chao-Chien, Chen, Ray-Jade, Sheu, Joen-Rong, Lin, Kuan-Hung

“…Basal macroautophagy/autophagy has recently been found in anucleate platelets. Platelet autophagy is involved in platelet activation and thrombus formation…”
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Host immune response to anti-cancer camptothecin conjugated cyclodextrin-based polymers by Chen, Yi-Fan, Wang, Yen-Hsin, Lei, Cing-Syuan, Changou, Chun A, Davis, Mark E, Yen, Yun

“…Efficacy and safety are critical concerns when designing drug carriers. Nanoparticles are a particular type of carrier that has gained recent attention in…”
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PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress by Kuo, Mei-Ling, Lee, Mabel Bin-Er, Tang, Michelle, den Besten, Willem, Hu, Shuya, Sweredoski, Michael J., Hess, Sonja, Chou, Chih-Ming, Changou, Chun A., Su, Mingming, Jia, Wei, Su, Leila, Yen, Yun

“…Ribonucleotide reductase small subunit B (RRM2B) is a stress response protein that protects normal human fibroblasts from oxidative stress. However, the…”
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Resveratrol inhibits human leiomyoma cell proliferation via crosstalk between integrin αvβ3 and IGF-1R by Ho, Yih, SH Yang, Yu-Chen, Chin, Yu-Tang, Chou, Szu-Yi, Chen, Yi-Ru, Shih, Ya-Jung, Whang-Peng, Jacqueline, Changou, Chun A., Liu, Hsuan-Liang, Lin, Shwu-Jiuan, Tang, Heng-Yuan, Lin, Hung-Yun, Davis, Paul J.

“…Leiomyomas (myomas) are the most common benign smooth muscle cell tumor of the myometrium. Resveratrol, a stilbene, has been used as an anti-inflammatory and…”
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Dual Inhibition of PIK3C3 and FGFR as a New Therapeutic Approach to Treat Bladder Cancer by Chen, Chun-Han, Changou, Chun A, Hsieh, Tsung-Han, Lee, Yu-Ching, Chu, Cheng-Ying, Hsu, Kai-Cheng, Wang, Hao-Ching, Lin, Yu-Chen, Lo, Yan-Ni, Liu, Yun-Ru, Liou, Jing-Ping, Yen, Yun

“…MPT0L145 has been developed as a FGFR inhibitor exhibiting significant anti-bladder cancer activity and via promoting autophagy-dependent cell death. Here, we…”
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Bridging Size and Charge Effects of Mesoporous Silica Nanoparticles for Crossing the Blood–Brain Barrier by Chen, Yi-Ping, Chou, Chih-Ming, Chang, Tsu-Yuan, Ting, Hao, Dembélé, Julien, Chu, You-Tai, Liu, Tsang-Pai, Changou, Chun A., Liu, Chien-Wei, Chen, Chien-Tsu

“…The blood–brain barrier (BBB) is a highly selective cellular barrier that tightly controls the microenvironment of the central nervous system to restrict the…”
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Thyroid hormone-induced expression of inflammatory cytokines interfere with resveratrol-induced anti-proliferation of oral cancer cells by Chen, Yi-Ru, Chen, Yu-Shen, Chin, Yu-Tang, Li, Zi-Lin, Shih, Ya-Jung, Yang, Yu-Chen S.H., ChangOu, Chun A., Su, Po-Yu, Wang, Shwu-Huey, Wu, Yun-Hsuan, Chiu, Hsien-Chung, Lee, Sheng-Yang, Liu, Leroy F., Whang-Peng, Jacqueline, Lin, Hung-Yun, Mousa, Shaker A., Davis, Paul J., Wang, Kuan

“…Thyroid hormone, L-thyroxine (T4), induces inflammatory genes expressions and promotes cancer growth. It also induces expression of the checkpoint programmed…”
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NDAT suppresses pro-inflammatory gene expression to enhance resveratrol-induced anti-proliferation in oral cancer cells by Ho, Yih, Wu, Chien-Yi, Chin, Yu-Tang, Li, Zi-Lin, Pan, Yi-shin, Huang, Tung-Yung, Su, Po-Yu, Lee, Sheng-Yang, Crawford, Dana R., Su, Kuan-Wei, Chiu, Hsien-Chung, Shih, Ya-Jung, Changou, Chun A., Yang, Yu-Chen S.H., Whang-Peng, Jaqulene, Chen, Yi-Ru, Lin, Hung-Yun, Mousa, Shaker A., Davis, Paul J., Wang, Kuan

“…Nano-diamino-tetrac (NDAT), a tetraiodothyroxine deaminated nano-particulated analog, has shown to inhibit expression of pro-inflammatory genes. NDAT inhibits…”
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Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization by Chen, Wei-Ta, Hsu, Wei-Tse, Yen, Meng-Hua, Changou, Chun A., Han, Chia-Li, Chen, Yu-Ju, Cheng, Ji-Yen, Chang, Tzu-Hao, Lee, Oscar Kuang-Sheng, Ho, Jennifer Hui-Chun

“…Mesenchymal stem cell (MSC) is mechanosensitive and the respond to mechanical force is pattern specific. We previously reported that oscillatory shear stress…”
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Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumor by Giang, Le Hien, Wu, Kuo-Sheng, Lee, Wei-Chung, Chu, Shing-Shung, Do, Anh Duy, Changou, Chun A, Tran, Huy Minh, Hsieh, Tsung-Han, Chen, Hsin-Hung, Hsieh, Chia-Ling, Sung, Shian-Ying, Yu, Alice L, Yen, Yun, Wong, Tai-Tong, Chang, Che-Chang

“…Atypical teratoid rhabdoid tumors (ATRT) is a rare but aggressive malignancy in the central nervous system, predominantly occurring in early childhood. Despite…”
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Heteronemin and tetrac derivatives suppress non-small cell lung cancer growth via ERK1/2 inhibition by Chung, Cheng-Chin, Huang, Tung-Yung, Chu, Hung-Ru, De Luca, Roberto, Candelotti, Elena, Huang, Chi-Hung, Yang, Yu-Chen S.H., Incerpi, Sandra, Pedersen, Jens Z., Lin, Chi-Yu, Huang, Haw-Ming, Lee, Sheng-Yang, Li, Zi-Lin, ChangOu, Chun A., Li, Wen-Shan, Davis, Paul J., Lin, Hung-Yun, Whang-Peng, Jacqueline, Wang, Kuan

“…The most common cancer, lung cancer, causes deaths worldwide. Most lung cancer patients have non-small cell lung carcinomas (NSCLCs) with a poor prognosis. The…”
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Chromatophagy: Autophagy goes nuclear and captures broken chromatin during arginine-starvation by Kung, Hsing-Jien, Changou, Chun A, Li, Chien-Feng, Ann, David K

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Type-3 Hyaluronan Synthase Attenuates Tumor Cells Invasion in Human Mammary Parenchymal Tissues by Lee, Wen-Jui, Tu, Shih-Hsin, Cheng, Tzu-Chun, Lin, Juo-Han, Sheu, Ming-Thau, Kuo, Ching-Chuan, Changou, Chun A, Wu, Chih-Hsiung, Chang, Hui-Wen, Chang, Hang-Lung, Chen, Li-Ching, Ho, Yuan-Soon

“…The microenvironment for tumor growth and developing metastasis should be essential. This study demonstrated that the hyaluronic acid synthase 3 (HAS3) protein…”
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