Search Results - "Chang-woo Lee"
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Soluble receptors in cancer: mechanisms, clinical significance, and therapeutic strategies
Published in Experimental & molecular medicine (01-02-2024)“…Soluble receptors are soluble forms of receptors found in the extracellular space. They have emerged as pivotal regulators of cellular signaling and disease…”
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2
Immunological distinctions between nonalcoholic steatohepatitis and hepatocellular carcinoma
Published in Experimental & molecular medicine (01-08-2020)“…Nonalcoholic fatty liver disease (NAFLD), the most common cause of chronic liver disease, ranges from simple hepatic steatosis to nonalcoholic steatohepatitis…”
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3
Ssu72 Dual-Specific Protein Phosphatase: From Gene to Diseases
Published in International journal of molecular sciences (06-04-2021)“…More than 70% of eukaryotic proteins are regulated by phosphorylation. However, the mechanism of dephosphorylation that counteracts phosphorylation is less…”
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4
Logical measurement-based quantum computation in circuit-QED
Published in Scientific reports (12-11-2019)“…We propose a new scheme of measurement-based quantum computation (MBQC) using an error-correcting code against photon-loss in circuit quantum electrodynamics…”
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5
Effects of Ag content on the interfacial reactions between liquid Sn–Ag–Cu solders and Cu substrates during soldering
Published in Journal of alloys and compounds (15-09-2016)“…The effects of Ag content on the interfacial reactions between Sn–Ag–Cu (SAC) solders and Cu substrates during soldering were studied based on an experiment in…”
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6
Dysregulation of cancer genes by recurrent intergenic fusions
Published in Genome Biology (06-07-2020)“…Abstract Background Gene fusions have been studied extensively, as frequent drivers of tumorigenesis as well as potential therapeutic targets. In many…”
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Densification Behavior of 316L Stainless Steel Parts Fabricated by Selective Laser Melting by Variation in Laser Energy Density
Published in MATERIALS TRANSACTIONS (01-01-2016)“…Selective laser melting (SLM) is an attractive manufacturing technique for the production of metal parts with complex geometries and high performance. This…”
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Ubiquitination Links DNA Damage and Repair Signaling to Cancer Metabolism
Published in International journal of molecular sciences (08-05-2023)“…Changes in the DNA damage response (DDR) and cellular metabolism are two important factors that allow cancer cells to proliferate. DDR is a set of events in…”
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Clearance of persistent HPV infection and cervical lesion by therapeutic DNA vaccine in CIN3 patients
Published in Nature communications (30-10-2014)“…Here, we demonstrate that electroporation-enhanced immunization with a rationally designed HPV DNA vaccine (GX-188E), preferentially targeting HPV antigens to…”
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10
TC Mps1 12, a novel Mps1 inhibitor, suppresses the growth of hepatocellular carcinoma cells via the accumulation of chromosomal instability
Published in British journal of pharmacology (01-06-2017)“…Background and Purpose Chromosomal instability is not only a hallmark of cancer but also an attractive therapeutic target. A diverse set of mitotic kinases…”
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A novel function of HRP‐3 in regulating cell cycle progression via the HDAC–E2F1–Cyclin E pathway in lung cancer
Published in Cancer science (01-01-2022)“…To improve the poor survival rate of lung cancer patients, we investigated the role of HDGF‐related protein 3 (HRP‐3) as a potential biomarker for lung cancer…”
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12
Pellino-1 expression is associated with epidermal proliferation and enhanced Th17 cell infiltration in psoriatic lesions
Published in Experimental dermatology (01-09-2023)“…Pellino-1 plays a crucial role in cellular proliferation and regulates inflammatory processes. This study investigated Pellino-1 expression patterns and their…”
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13
Pellino1 regulates reversible ATM activation via NBS1 ubiquitination at DNA double-strand breaks
Published in Nature communications (05-04-2019)“…DNA double-strand break (DSB) signaling and repair are critical for genome integrity. They rely on highly coordinated processes including posttranslational…”
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14
Surface treatment of silica nanoparticles for stable and charge-controlled colloidal silica
Published in International journal of nanomedicine (15-12-2014)“…An attempt was made to control the surface charge of colloidal silica nanoparticles with 20 nm and 100 nm diameters. Untreated silica nanoparticles were…”
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15
Effect of laser power on oxygen and nitrogen concentration of commercially pure titanium manufactured by selective laser melting
Published in Materials characterization (01-09-2018)“…This study analyzed the variation of mechanical properties and its causes with increasing the laser power in the fabrication of pure titanium by selective…”
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16
Chitosan complements entrapment of silicon inside nitrogen doped carbon to improve and stabilize the capacity of Li-ion batteries
Published in Scientific reports (01-03-2019)“…A facile strategy to entrap milled silicon (m-Si) particles using nitrogen-doped-carbon (N-C@m-Si) to overcome the dramatic volume changes in Si during…”
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17
Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation
Published in Nature communications (25-02-2023)“…Brown adipose tissue (BAT) plays a pivotal role in maintaining body temperature and energy homeostasis. BAT dysfunction is associated with impaired metabolic…”
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18
The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation
Published in Nature communications (21-09-2018)“…Chromatin remodelers regulate the nucleosome barrier during transcription, DNA replication, and DNA repair. The chromatin remodeler RSF1 is enriched at mitotic…”
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19
Polo-like kinase 1 inhibitor BI2536 causes mitotic catastrophe following activation of the spindle assembly checkpoint in non-small cell lung cancer cells
Published in Cancer letters (28-02-2015)“…Abstract Polo-like kinase 1 (PLK1), a critical kinase that regulates multiple steps in mitosis, is overexpressed in diverse human cancers; thus many PLK1…”
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PLOD3 suppression exerts an anti-tumor effect on human lung cancer cells by modulating the PKC-delta signaling pathway
Published in Cell death & disease (15-02-2019)“…Current lung cancer treatments are far from satisfactory; thus, finding novel treatment targets is crucial. We recently identified procollagen-lysine,…”
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