Search Results - "Chang, Xingyu"
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New perspective into mesenchymal stem cells: Molecular mechanisms regulating osteosarcoma
Published in Journal of bone oncology (01-08-2021)“…•The origin of osteosarcoma cells from osteoblasts and mesenchymal stem cells remains controversial.•Mesenchymal stem cells regulate the development of…”
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2
miRNA, lncRNA and circRNA: Targeted Molecules Full of Therapeutic Prospects in the Development of Diabetic Retinopathy
Published in Frontiers in endocrinology (Lausanne) (10-11-2021)“…Diabetic retinopathy (DR) is a common diabetic complication and the main cause of blindness worldwide, which seriously affects the quality of life of patients…”
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3
Role of Pyroptosis in Intervertebral Disc Degeneration and Its Therapeutic Implications
Published in Biomolecules (Basel, Switzerland) (01-12-2022)“…Intervertebral disc degeneration (IDD), a progressive and multifactorial pathological process, is predominantly associated with low back pain and permanent…”
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4
The prevalence of subclinical hypothyroidism in a pre-diabetes population and an analysis of related factors
Published in Annals of medicine (Helsinki) (01-12-2023)“…The prevalence of subclinical hypothyroidism (SCH) in the pre-diabetic population was analysed by cross-sectional survey. There is a great deviation in the…”
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5
Research Progress of Nanomaterials in Chemotherapy of Osteosarcoma
Published in Orthopaedic surgery (01-09-2023)“…Osteosarcoma (OS) is a common malignant bone tumor that occurs mostly in children and adolescents. At present, surgery after chemotherapy or postoperative…”
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Evaluation of bi-directional causal association between obstructive sleep apnoea syndrome and diabetic microangiopathy: a Mendelian randomization study
Published in Frontiers in cardiovascular medicine (09-05-2024)“…The relationship between obstructive sleep apnea syndrome (OSAS) and diabetic microangiopathy remains controversial. This study aimed to use bidirectional…”
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7
Intermittent Fasting to the Eye: A New Dimension Involved in Physiological and Pathological Changes
Published in Frontiers in medicine (24-05-2022)“…Intermittent fasting (IF) is gaining popularity as a therapeutic dietary strategy that regulates metabolism and can alter the development of metabolic…”
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Tumor-Targeting NHC–Au(I) Complex Induces Immunogenic Cell Death in Hepatocellular Carcinoma
Published in Journal of medicinal chemistry (23-03-2023)“…Immunogenic cell death (ICD) is a promising direction of cancer immunotherapy in hepatocellular carcinoma (HCC). A series of novel NHC–Au(I) complexes derived…”
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Induction of immunogenic cell death by novel platinum-based anticancer agents
Published in Pharmacological research (01-01-2023)“…Traditional platinum-based anticancer drugs, led by cisplatin, play an important role in chemotherapy. However, the development of platinum compounds is…”
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10
Targeting the NLRP3 inflammasome in diabetic retinopathy: From pathogenesis to therapeutic strategies
Published in Biochemical pharmacology (01-06-2023)“…[Display omitted] Diabetic retinopathy (DR) is a common diabetic microvascular complication and the main cause of vision loss in working-aged people. The NLRP3…”
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More than just DNA damage: Pt(ΙΙ)-NHC complexes derived from 4,5-diarylimidazoles augment immunogenic cell death
Published in European journal of medicinal chemistry (15-01-2025)“…Platinum-based drugs are a mainstay in chemotherapy, with traditional forms exerting their work directly on DNA. In recent years, it has been observed that…”
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CircRNA: A novel potential strategy to treat thyroid cancer (Review)
Published in International journal of molecular medicine (01-11-2021)“…Thyroid cancer (TC) is the most common type of endocrine cancer. Over the last 50 years, the global incidence of TC has been increasing. The survival rate of…”
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CircRNAs: promising factors for regulating angiogenesis in colorectal cancer
Published in Clinical & translational oncology (01-09-2022)“…Colorectal cancer (CRC) is one of the most common cancers in the world. The incidence rate of cancer is high. The overall response to traditional treatment…”
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Biotin-Targeted Au(I) Radiosensitizer for Cancer Synergistic Therapy by Intervening with Redox Homeostasis and Inducing Ferroptosis
Published in Journal of medicinal chemistry (23-06-2022)“…The search for highly selective sensitizers with a novel mechanism for tumor targeting therapy is of considerable interest. In this work, we have developed a…”
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15
Pyroptosis: A Novel Intervention Target in the Progression of Osteoarthritis
Published in Journal of inflammation research (01-01-2022)“…Osteoarthritis (OA) is one of the most common chronic joint diseases and is gradually becoming the main cause of disability and joint pain in the elderly…”
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16
The Detection of Thyroid Nodules in Prediabetes Population and Analysis of Related Factors
Published in Risk management and healthcare policy (31-12-2021)“…Purpose: To explore the detection of thyroid nodules (TN) and related influencing factors in the population of prediabetes (PreDM) in northwest China's Gansu…”
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The Detection of Thyroid Nodules in Prediabetes Population and Analysis of Related Factors
Published in Risk management and healthcare policy (01-01-2021)“…To explore the detection of thyroid nodules (TN) and related influencing factors in the population of prediabetes (PreDM) in northwest China's Gansu Province…”
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