Search Results - "Chang, Weise"
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Gradients of glucose metabolism regulate morphogen signalling required for specifying tonotopic organization in the chicken cochlea
Published in eLife (04-08-2023)“…In vertebrates with elongated auditory organs, mechanosensory hair cells (HCs) are organised such that complex sounds are broken down into their component…”
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2
Blast-induced hearing impairment in rats is associated with structural and molecular changes of the inner ear
Published in Scientific reports (30-06-2020)“…Auditory dysfunction is the most prevalent injury associated with blast overpressure exposure (BOP) in Warfighters and civilians, yet little is known about the…”
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3
Bmp4 is essential for the formation of the vestibular apparatus that detects angular head movements
Published in PLoS genetics (01-04-2008)“…Angular head movements in vertebrates are detected by the three semicircular canals of the inner ear and their associated sensory tissues, the cristae. Bone…”
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4
Patterning and morphogenesis of the vertebrate inner ear
Published in The International journal of developmental biology (2007)“…The positional cues for formation of individual inner ear components are dependent on pre-established axial information conferred by inductive signals from…”
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5
Expression and function of scleraxis in the developing auditory system
Published in PloS one (13-09-2013)“…A study of genes expressed in the developing inner ear identified the bHLH transcription factor Scleraxis (Scx) in the developing cochlea. Previous work has…”
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6
A New Compartment at Stereocilia Tips Defined by Spatial and Temporal Patterns of Myosin IIIa Expression
Published in The Journal of neuroscience (04-10-2006)“…Class III myosins are motor proteins that contain an N-terminal kinase domain and a C-terminal actin-binding domain. We show that myosin IIIa, which has been…”
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7
The role of Pax2 in mouse inner ear development
Published in Developmental biology (01-08-2004)“…The paired box transcription factor, Pax2, is important for cochlear development in the mouse inner ear. Two mutant alleles of Pax2, a knockout and a…”
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8
The development of semicircular canals in the inner ear: role of FGFs in sensory cristae
Published in Development (Cambridge) (01-09-2004)“…In the vertebrate inner ear, the ability to detect angular head movements lies in the three semicircular canals and their sensory tissues, the cristae. The…”
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9
BMP Pathways Are Involved in Otic Capsule Formation and Epithelial–Mesenchymal Signaling in the Developing Chicken Inner Ear
Published in Developmental biology (15-11-2002)“…The vertebrate inner ear consists of a complex labyrinth of epithelial cells that is surrounded by a bony capsule. The molecular mechanisms coordinating the…”
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10
Ectopic Noggin Blocks Sensory and Nonsensory Organ Morphogenesis in the Chicken Inner Ear
Published in Developmental biology (01-12-1999)“…Bone morphogenetic protein 4 (Bmp4) is expressed during multiple stages of development of the chicken inner ear. At the otocyst stage, Bmp4 is expressed in…”
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11
Calnexin-dependent Enhancement of Nicotinic Acetylcholine Receptor Assembly and Surface Expression
Published in The Journal of biological chemistry (14-11-1997)“…The muscle-type nicotinic acetylcholine receptor (AChR)2 is a pentameric membrane ion channel assembled in the endoplasmic reticulum from four homologous…”
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12
Rbpj regulates development of prosensory cells in the mammalian inner ear
Published in Developmental biology (15-05-2011)“…The vertebrate inner ear contains multiple sensory patches comprised of hair cells and supporting cells. During development these sensory patches arise from…”
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13
Role of the Endoplasmic Reticulum Chaperone Calnexin in Subunit Folding and Assembly of Nicotinic Acetylcholine Receptors (∗)
Published in The Journal of biological chemistry (23-06-1995)“…The nicotinic acetylcholine receptor (AChR) is a pentameric complex assembled from four different gene products by mechanisms that are inadequately understood…”
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14
Retinoic acid signalling regulates the development of tonotopically patterned hair cells in the chicken cochlea
Published in Nature communications (20-05-2014)“…Precise frequency discrimination is a hallmark of auditory function in birds and mammals and is required for distinguishing similar sounding words, like ‘bat,’…”
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15
Spectrum of genes for inherited hearing loss in the Israeli Jewish population, including the novel human deafness gene ATOH1
Published in Clinical genetics (01-10-2020)“…Mutations in more than 150 genes are responsible for inherited hearing loss, with thousands of different, severe causal alleles that vary among populations…”
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16
A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear
Published in Nature communications (20-05-2014)“…The auditory systems of animals that perceive sounds in air are organized to separate sound stimuli into their component frequencies. Individual tones then…”
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17
Correction: Corrigendum: A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear
Published in Nature communications (01-08-2014)“…Nature Communications 5: Article number: 3839 (2014); Published: 20 May 2014; Updated: 1 August 2014. In this Article, several graphs in Fig. 2 have an…”
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18
Bmp4 Is Essential for the Formation of the Vestibular Apparatus that Detects Angular Head Movements: e1000050
Published in PLoS genetics (01-04-2008)“…Angular head movements in vertebrates are detected by the three semicircular canals of the inner ear and their associated sensory tissues, the cristae. Bone…”
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19
Corrigendum: A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear
Published in Nature communications (01-08-2014)Get full text
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20
Identification of Phosphorylation Sites on AChR δ-Subunit Associated with Dispersal of AChR Clusters on the Surface of Muscle Cells
Published in Biochemistry (Easton) (20-10-1998)“…The innervation of embryonic skeletal muscle cells is marked by the redistribution of nicotinic acetylcholine receptors (AChRs) on muscle surface membranes…”
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