Search Results - "Chang, Stacey"

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  1. 1

    Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule by Li, Wenfei, Ward, Fred R., McClure, Kim F., Chang, Stacey Tsai-Lan, Montabana, Elizabeth, Liras, Spiros, Dullea, Robert G., Cate, Jamie H. D.

    Published in Nature structural & molecular biology (01-06-2019)
    “…The drug-like molecule PF-06446846 (PF846) binds the human ribosome and selectively blocks the translation of a small number of proteins by an unknown…”
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    Journal Article
  2. 2

    Selective inhibition of human translation termination by a drug-like compound by Li, Wenfei, Chang, Stacey Tsai-Lan, Ward, Fred. R., Cate, Jamie H. D.

    Published in Nature communications (02-10-2020)
    “…Methods to directly inhibit gene expression using small molecules hold promise for the development of new therapeutics targeting proteins that have evaded…”
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    A highly efficient human cell-free translation system by Aleksashin, Nikolay A, Chang, Stacey Tsai-Lan, Cate, Jamie H D

    Published in RNA (Cambridge) (01-12-2023)
    “…Cell-free protein synthesis (CFPS) systems enable easy in vitro expression of proteins with many scientific, industrial, and therapeutic applications. Here we…”
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    Beyond Evidence-Based Medicine by Chang, Stacey, Lee, Thomas H

    Published in The New England journal of medicine (22-11-2018)
    “…Evidence-based medicine shifted medicine’s center of gravity away from the space between clinician and patient. A new “interpersonal medicine” would be a…”
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  8. 8

    The presence of preoperative neurodegeneration biofluid markers in patients with postoperative delirium by Leung, Jacqueline M., Rojas, Julio C., Tang, Christopher, Chan, Brandon, Lario-Lago, Argentina, Boxer, Adam L., Do, Quyen, Kramer, Joel H., Du, Zhiyuan, Du, Pang, Sands, Laura P.

    Published in Anesthesiology (Philadelphia) (01-10-2023)
    “…The pathophysiology of delirium is incompletely understood, including what molecular pathways are involved in brain vulnerability to delirium. This study…”
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    Cannabis-based medicinal products: summary of NICE guidance by Chang-Douglass, Stacey, Mulvihill, Caroline, Pilling, Steve

    Published in BMJ (Online) (21-04-2020)
    “…Do not offer CBD to manage chronic pain in adults unless as part of a clinical trial In September 2018, in light of the UK chief medical officer’s review and…”
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  11. 11

    Cost-effectiveness of asenapine in the treatment of bipolar I disorder patients with mixed episodes by Sawyer, Laura, Azorin, Jean-Michel, Chang, Stacey, Rinciog, Claudia, Guiraud-Diawara, Alice, Marre, Caroline, Hansen, Karina

    Published in Journal of medical economics (01-07-2014)
    “…Around one-third of patients with bipolar I disorder (BD-I) experience mixed episodes, characterized by both mania and depression, which tend to be more…”
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  12. 12

    Costs and Health Outcomes Associated with Tofacitinib Treatment for Active Psoriatic Arthritis in the United States by Bungey, George, Chang-Douglass, Stacey, Hsu, Ming-Ann, Cappelleri, Joseph C, Young, Pamela, Woolcott, John

    “…Psoriatic arthritis (PsA) is a chronic progressive inflammatory condition associated with significant direct and indirect costs. Tofacitinib is an oral Janus…”
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