Search Results - "Chang, Shaohong"

A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity by Xu, Xiaojie, Fan, Zhongyi, Liang, Chaoyang, Li, Ling, Wang, Lili, Liang, Yingchun, Wu, Jun, Chang, Shaohong, Yan, Zhifeng, Lv, Zhaohui, Fu, Jing, Liu, Yang, Jin, Shuai, Wang, Tao, Hong, Tian, Dong, Yishan, Ding, Lihua, Cheng, Long, Liu, Rui, Fu, Shenbo, Jiao, Shunchang, Ye, Qinong

“…Tumour radiotherapy resistance involves the cell cycle pathway. CDC25 phosphatases are key cell cycle regulators. However, how CDC25 activity is precisely…”
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PES1 is a critical component of telomerase assembly and regulates cellular senescence by Cheng, Long, Yuan, Bin, Ying, Sunyang, Niu, Chang, Mai, Hongxu, Guan, Xin, Yang, Xiaohui, Teng, Yan, Lin, Jing, Huang, Junjian, Jin, Rui, Wu, Jun, Liu, Bo, Chang, Shaohong, Wang, Enqun, Zhang, Chunxia, Hou, Ning, Cheng, Xuan, Xu, Danyang, Yang, Xiao, Gao, Shan, Ye, Qinong

“…Telomerase defers the onset of telomere shortening and cellular senescence by adding telomeric repeat DNA to chromosome ends, and its activation contributes to…”
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Disruption of the OCH1 and MNN1 genes decrease N-glycosylation on glycoprotein expressed in Kluyveromyces lactis by Liu, Bo, Gong, Xin, Chang, Shaohong, Yang, Yili, Song, Miao, Duan, Demin, Wang, Lina, Ma, Qingjun, Wu, Jun

“…Glycoproteins secreted by the yeast Kluyveromyces lactis are usually modified by the addition at asparagines-linked glycosylation sites of heterogeneous mannan…”
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Generation of Mature Nα-Terminal Acetylated Thymosin α1 by Cleavage of Recombinant Prothymosin α by Wu, Jun, Sun, Peng, Chang, Shaohong, Gong, Xin, Liu, Bo

“…Nα-terminal acetylation of peptides plays an important biological role but is rarely observed in prokaryotes. Nα-terminal acetylated thymosin α1 (Tα1), a…”
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Recombinant H7 hemagglutinin expressed in glycoengineered Pichia pastoris forms nanoparticles that protect mice from challenge with H7N9 influenza virus by Liu, Bo, Shi, Pingping, Wang, Tiantian, Zhao, Yongkun, Lu, Shihao, Li, Xiang, Luo, Shiqiang, Chang, Shaohong, Wang, Sha, Sun, Peng, Gong, Xin, Gao, Yuwei, Wu, Jun

“…•The rH7 was expressed successfully in glycoengineered Pichia pastoris system.•The rH7 had complex glycosylation modifications and polymerized to…”
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Engineering O -glycosylation in modified N -linked oligosaccharide (Man 12 GlcNAc 2 ∼Man 16 GlcNAc 2 ) Pichia pastoris strains by Li, Siqiang, Sun, Peng, Gong, Xin, Chang, Shaohong, Li, Enzhong, Xu, Yuanhong, Wu, Jun, Liu, Bo

“…Yeast have been engineered for the production of therapeutic glycoproteins with humanized -linked oligosaccharides. Both - and -linked oligosaccharides…”
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Characterization and immunological activity of different forms of recombinant secreted Hc of botulinum neurotoxin serotype B products expressed in yeast by Liu, Bo, Shi, DanYang, Chang, ShaoHong, Gong, Xin, Yu, YunZhou, Sun, ZhiWei, Wu, Jun

“…The recombinant Hc proteins of botulinum neurotoxins and tetanus toxin are exclusively produced by intracellular heterologous expression in Pichia pastoris for…”
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Engineering O-glycosylation in modified N-linked oligosaccharide (Man12GlcNAc2∼Man16GlcNAc2) Pichia pastoris strainsElectronic supplementary information (ESI) available. See DOI: 10.1039/c8ra08121b by Li, Siqiang, Sun, Peng, Gong, Xin, Chang, Shaohong, Li, Enzhong, Xu, Yuanhong, Wu, Jun, Liu, Bo

“…Yeast have been engineered for the production of therapeutic glycoproteins with humanized N -linked oligosaccharides. Both N - and O -linked oligosaccharides…”
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Generation of mature [N.sup.α]-terminal acetylated thymosin α1 by cleavage of recombinant prothymosin α by Liu, Bo, Gong, Xin, Chang, Shaohong, Sun, Peng, Wu, Jun

“…[N.sup.α]-terminal acetylation of peptides plays an important biological role but is rarely observed in prokaryotes. [N.sup.α]-terminal acetylated thymosin α1…”
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Generation of mature Nα-terminal acetylated thymosin α 1 by cleavage of recombinant prothymosin α by Liu, Bo, Gong, Xin, Chang, Shaohong, Sun, Peng, Wu, Jun

“…N(α)-terminal acetylation of peptides plays an important biological role but is rarely observed in prokaryotes. N(α)-terminal acetylated thymosin α1 (Tα1), a…”
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Identification of N-terminal acetylation of recombinant human prothymosin α in Escherichia coli by Wu, Jun, Chang, Shaohong, Gong, Xing, Liu, Dianxin, Ma, Qingjun

“…Functional modification of protein through N-terminal acetylation is common in eukaryotes but rare in prokaryotes. Prothymosin α is an essential protein in…”
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Construction of yeast Pichia pastoris to produce Man5GlcNAc2 mammalian mannose-type glycoprotein by Yang, Xiaopeng, Liu, Bo, Song, Miao, Gong, Xin, Chang, Shaohong, Xue, Kuijing, Wu, Jun

“…Glycosylation is vital for activity, higher structure and function of protein. Glycoproteins derived from yeast contain N-glycan of high mannose type and are…”
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Cloning of IL-1 beta gene and expression in E. coli by Chang, Shaohong, Wu, Jun, Gong, Xin

“…IL-1 beta cDNA was obtained by RT-PCR with the template of the total RNA extracted from leukocytes which was separated from human peripheral blood. 5' and 3'…”
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