Search Results - "Chang, Patrick C"

PAMAM versus PEI complexation for siRNA delivery: interaction with model lipid membranes and cellular uptake by Chang, Patrick K. C., Prestidge, Clive A., Bremmell, Kristen E.

“…Purpose Cationic polymers have many advantages as vectors for mediated cellular entry and delivery of siRNA. However, toxicity related to their cationic charge…”
Get full text

Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing by McAuley, Grace E., Yiu, Gloria, Chang, Patrick C, Newby, Gregory A., Campo-Fernandez, Beatriz, Fitz-Gibbon, Sorel T., Wu, Xiaomeng, Kang, Sung-Hae L., Garibay, Amber, Butler, Jeffrey, Christian, Valentina, Wong, Ryan L., Everette, Kelcee A., Azzun, Anthony, Gelfer, Hila, Seet, Christopher S., Narendran, Aru, Murguia-Favela, Luis, Romero, Zulema, Wright, Nicola, Liu, David R., Crooks, Gay M., Kohn, Donald B.

“…CD3δ SCID is a devastating inborn error of immunity caused by mutations in CD3D, encoding the invariant CD3δ chain of the CD3/TCR complex necessary for normal…”
Get full text

Association of Standardized Radiology Reporting and Management of Abdominal CT and MRI With Diagnosis of Pancreatic Cancer by Ormsby, Eleanor L., Kojouri, Kourosh, Chang, Patrick C., Lin, Teresa Y., Vuong, Brooke, Ramirez, Rene M., Schueler, Kristin M., Sweet, Clifford F., Herrinton, Lisa J.

“…Follow-up of abdominal computed tomography (CT) and magnetic resonance imaging (MRI) findings suspicious for pancreatic cancer may be delayed if documentation…”
Get full text

Generation of antigen-specific mature T cells from RAG1−/−RAG2−/−B2M−/− stem cells by engineering their microenvironment by Chang, Patrick C, Yuan, Xuegang, Zampieri, Alexandre, Towns, Chloe, Yoo, Sang Pil, Engstrom, Claire, Tsai, Steven, Robles, Christopher R., Zhu, Yuhua, Lopez, Shawn, Montel-Hagen, Amelie, Seet, Christopher S., Crooks, Gay M.

“…Pluripotent stem cells (PSCs) are a promising source of allogeneic T cells for off-the-shelf immunotherapies. However, the process of differentiating…”
Get full text

Central Skull Base Osteomyelitis in Patients without Otitis Externa: Imaging Findings by Chang, Patrick C, Fischbein, Nancy J, Holliday, Roy A

“…Skull base osteomyelitis typically arises as a complication of ear infection in older diabetic patients, involves the temporal bone, and has Pseudomonas…”
Get full text

Perineural Spread of Malignant Melanoma of the Head and Neck: Clinical and Imaging Features by Chang, Patrick C, Fischbein, Nancy J, McCalmont, Timothy H, Kashani-Sabet, Mohammed, Zettersten, Elizabeth M, Liu, Amon Y, Weissman, Jane L

“…Extension of malignant melanoma along cranial nerves is a little-known complication of malignant melanoma of the head and neck. We describe the clinical and MR…”
Get full text

Interfacial analysis of siRNA complexes with poly-ethylenimine (PEI) or PAMAM dendrimers in gene delivery by Chang, Patrick K.C., Prestidge, Clive A., Bremmell, Kristen E.

“…•Polymer-siRNA complexation and impact on interfacial adsorption.•Size and structure of polymeric vector influences the complexed siRNA…”
Get full text

DTI-based three-dimensional tractography detects differences in the pyramidal tracts of infants and children with congenital hemiparesis by Glenn, Orit A., Henry, Roland G., Berman, Jeffrey I., Chang, Patrick C., Miller, Steven P., Vigneron, Daniel B., Barkovich, A. James

“…Purpose To test the hypothesis that there is greater asymmetry in diffusion properties between right and left pyramidal tracts in patients with congenital…”
Get full text

Tophaceous gout of the first costochondral junction in a heart transplant patient by CHANG, Patrick C, SEEGER, Leanne L, MOTAMEDI, Kambiz, CHAN, Jessica B

“…We report the case of a 49-year-old man with a 10-year history of gout, who presented with a painful left first costochondral junction mass. A computed…”
Get full text

‘Can you point to where the abnormality is?’: Pelvic digit, a case report by Lohan, Derek G, Chang, Patrick C, Motamedi, Kambiz, Seeger, Leanne L

“…Abstract Pelvic digit is a rare congenital anomaly that may be misinterpreted as neoplasm or a post-traumatic condition. Failure to recognize this phenomenon…”
Get full text

In vitro Generation of Antigen-Specific, Class I MHC-Null, Cytotoxic T Cells for Immunotherapy by Chang, Patrick C

“…While T cell-based immunotherapies using cells expressing antigen-specific receptors (CARs or TCRs) have produced promising clinical responses, current…”
Get full text

Connective Tissue Growth Factor Induces Anti-Apoptotic Factors in Chronic Myeloid Leukemia Stem Cells by Chang, Patrick C, Low-Marchelli, Janine M, Shahbandi, Ashkan, Goff, Daniel J, Jamieson, Catriona

“…Chronic Myeloid Leukemia (CML) is a progressive hematopoietic malignancy where expression of the oncogenic fusion protein BCR-ABL1 in leukemia stem cells…”
Get full text

The role of CTGF in chronic myeloid leukemia stem cell maintenance by Chang, Patrick C

“…Chronic myeloid leukemia (CML) results from the BCR-ABL1 fusion protein that skews hematopoietic stem cell differentiation toward the myeloid lineage, creating…”
Get full text

Manufacture of microcellular open-celled polyolefin foams by Lee, Chang-Dong Patrick

“…A continuous extrusion process for the manufacture of microcellular and open-celled polyolefin foams is presented. The major plastics used in this study were…”
Get full text