Search Results - "Chang, Myron N"

Randomized, controlled trial of standard, large-capacity versus jumbo biopsy forceps for polypectomy of small, sessile, colorectal polyps by Draganov, Peter V., MD, Chang, Myron N., PhD, Alkhasawneh, Ahmad, MD, Dixon, Lisa R., MD, Lieb, John, MD, Moshiree, Baharak, MD, Polyak, Steven, MD, Sultan, Shahnaz, MD, Collins, Dennis, MD, Suman, Amitabh, MD, Valentine, John F., MD, Wagh, Mihir S., MD, Habashi, Samir L., MD, Forsmark, Chris E., MD

“…Background Polypectomy with cold biopsy forceps is a frequently used technique for removal of small, sessile, colorectal polyps. Jumbo forceps may lead to more…”
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Cardiomyopathy in Children With Down Syndrome Treated for Acute Myeloid Leukemia: A Report From the Children's Oncology Group Study POG 9421 by O'BRIEN, Maureen M, TAUB, Jeffrey W, CHANG, Myron N, MASSEY, Gita V, STINE, Kimo C, RAIMONDI, Susana C, BECTON, David, RAVINDRANATH, Yaddanapudi, DAHL, Gary V

“…To determine the outcomes, with particular attention to toxicity, of children with Down syndrome (DS) and acute myeloid leukemia (AML) treated on Pediatric…”
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A statistical design for testing transgenerational genomic imprinting in natural human populations by Li, Yao, Guo, Yunqian, Wang, Jianxin, Hou, Wei, Chang, Myron N, Liao, Duanping, Wu, Rongling

“…Genomic imprinting is a phenomenon in which the same allele is expressed differently, depending on its parental origin. Such a phenomenon, also called the…”
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Effect of bevacizumab on angiogenesis and growth of canine osteosarcoma cells xenografted in athymic mice by Scharf, Valery F, Farese, James P, Coomer, Alastair R, Milner, Rowan J, Taylor, David P, Salute, Marc E, Chang, Myron N, Neal, Dan, Siemann, Dietmar W

“…Objective-To investigate the effects of bevacizumab, a human monoclonal antibody against vascular endothelial growth factor, on the angiogenesis and growth of…”
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Tandem Autologous Stem Cell Transplantation for Multiple Myeloma Patients Based on Response to Their First Transplant-A Prospective Phase II Study by Byrne, Michael, Salmasinia, Donya, Leather, Helen, Cogle, Christopher R., Davis, Amy, Hsu, Jack W., Wiggins, Laura, Chang, Myron N., An, Qi, Wingard, John R., Moreb, Jan S.

“…In this prospective phase II clinical trial, multiple myeloma (MM) patients were randomized to receive a second (tandem) autologous stem cell transplantation…”
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A prospective study of the natural history of transient leukemia (TL) in neonates with Down syndrome (DS): Children's Oncology Group (COG) study POG-9481 by Massey, Gita V., Zipursky, Alvin, Chang, Myron N., Doyle, John J., Nasim, Suhail, Taub, Jeffrey W., Ravindranath, Yaddanapudi, Dahl, Gary, Weinstein, Howard J.

“…A unique transient leukemia (TL) has been described in newborns with Down syndrome (DS; or trisomy 21 mosaics). This leukemia has a high incidence of…”
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Autologous Bone Marrow Transplantation versus Intensive Consolidation Chemotherapy for Acute Myeloid Leukemia in Childhood by Ravindranath, Yaddanapudi, Yeager, Andrew M, Chang, Myron N, Steuber, C. Philip, Krischer, Jeffrey, Graham-Pole, John, Carroll, Andrew, Inoue, Susumu, Camitta, Bruce, Weinstein, Howard J

“…Chemotherapy can induce a remission in up to 85 percent of children with acute myeloid leukemia (AML). 1 – 7 However, most patients relapse, and the long-term…”
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Improved two-stage tests for stratified phase II cancer clinical trials by Chang, Myron N., Shuster, Jonathan J., Hou, Wei

“…In a single‐arm, two‐stage, phase II cancer clinical trial for efficacy screening of cytotoxic agents, a common primary endpoint is a binary (yes/no) patient…”
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Designs for randomized phase II clinical trials with two treatment arms by Hou, Wei, Chang, Myron N., Jung, Sin-Ho, Li, Yang

“…The most common primary statistical end point of a phase II clinical trial is the categorization of a patient as either a ‘responder’ or ‘nonresponder’. The…”
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Su1597 Predictive Factors for Percutaneous Drainage Placement in Patients Developing Bilomas From Bile Leaks by Rivera, Mari A, Rajca, Brian, Forsmark, Christopher E, Draganov, Peter V, Wagh, Mihir S, Gupte, Anand, Chang, Myron N, Dai, Yunfeng, Chauhan, Shailendra

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Increased IL-6 detection in adult and pediatric lymphoid tissue harboring Parvovirus B19 by Polcz, Monica E, Adamson, Laura A, Lu, Xiaomin, Chang, Myron N, Fowler, Larry J, Hobbs, Jacqueline A

“…Abstract Background Parvovirus B19 (B19V) is a common pathogenic virus infecting humans. Previous studies have shown evidence of B19V infection in patients…”
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Biologic Behavior and Clinical Outcome of 25 Dogs with Canine Appendicular Chondrosarcoma Treated by Amputation: A Veterinary Society of Surgical Oncology Retrospective Study by FARESE, JAMES P, KIRPENSTEIJN, JOLLE, KIK, MARJA, BACON, NICHOLAS J, WALTMAN, SUZANNE SHELLY, SEGUIN, BERNARD, KENT, MICHAEL, LIPTAK, JULIUS, STRAW, ROD, CHANG, MYRON N, JIANG, YANG, WITHROW, STEPHEN J

“…To characterize biologic behavior, clinical outcome, and effect of histologic grade on prognosis for dogs with appendicular chondrosarcoma treated by…”
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One- and two-stage designs for phase II window studies by Chang, Myron N., Devidas, Meenakshi, Anderson, James

“…The primary goal of phase II window studies in cancer is testing new single agents or combination therapies for newly diagnosed patients who are less likely to…”
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One- and two-stage designs for stratified phase II clinical trials by London, Wendy B., Chang, Myron N.

“…A global one‐sample test for response rates for stratified phase II clinical trials is proposed. Such a test is analogous to that of a stratified log‐rank test…”
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Testing Statistical Hypotheses on Stochastic Ordering of Discrete Distributions by Chang, Myron N.

“…Let F 0 and F be distribution functions over a finite sample space. We propose methods to test whether F is stochastically smaller than F 0 based on a random…”
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Randomized use of cyclosporin A (CsA) to modulate P-glycoprotein in children with AML in remission: Pediatric Oncology Group Study 9421 by Becton, David, Dahl, Gary V., Ravindranath, Yaddanapudi, Chang, Myron N., Behm, Fred G., Raimondi, Susana C., Head, David R., Stine, Kimo C., Lacayo, Norman J., Sikic, Branimir Ivan, Arceci, Robert J., Weinstein, Howard

“…Relapse is a major obstacle in the cure of acute myeloid leukemia (AML). The Pediatric Oncology Group AML Study 9421 tested 2 different strategies to improve…”
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Gene expression profiles at diagnosis in de novo childhood AML patients identify FLT3 mutations with good clinical outcomes by Lacayo, Norman J., Meshinchi, Soheil, Kinnunen, Paivi, Yu, Ron, Wang, Yan, Stuber, Christianna M., Douglas, Lorrie, Wahab, Romina, Becton, David L., Weinstein, Howard, Chang, Myron N., Willman, Cheryl L., Radich, Jerald P., Tibshirani, Robert, Ravindranath, Yaddanapudi, Sikic, Branimir I., Dahl, Gary V.

“…Fms-like tyrosine kinase 3 (FLT3) mutations are associated with unfavorable outcomes in children with acute myeloid leukemia (AML). We used DNA microarrays to…”
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Phase II Cancer Clinical Trials with Heterogeneous Patient Populations by Jung, Sin-Ho, Chang, Myron N., Kang, Sun J.

“…The patient population for a Phase II trial often consists of multiple subgroups in terms of risk level. In this case, a popular design approach is to specify…”
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Phase I study of valspodar (PSC-833) with mitoxantrone and etoposide in refractory and relapsed pediatric acute leukemia: A report from the Children's Oncology Group by O'Brien, Maureen M., Lacayo, Norman J., Lum, Bert L., Kshirsagar, Smita, Buck, Steven, Ravindranath, Yaddanapudi, Bernstein, Mark, Weinstein, Howard, Chang, Myron N., Arceci, Robert J., Sikic, Branimir I., Dahl, Gary V.

“…Background Valspodar, a non‐immunosuppressive analog of cylosporine, is a potent P‐glycoprotein (MDR1) inhibitor. As MDR1‐mediated efflux of chemotherapeutic…”
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Score statistics for mapping quantitative trait loci by Chang, Myron N, Wu, Rongling, Wu, Samuel S, Casella, George

“…We propose a method to detect the existence of quantitative trait loci (QTL) in a backcross population using a score test. Since the score test only uses the…”
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