Search Results - "Chang, Lihua"

Microplastics aggravates rheumatoid arthritis by affecting the proliferation/migration/inflammation of fibroblast-like synovial cells by regulating mitochondrial homeostasis by Lihua, Chang, Zhiyin, Tang

“…•Microplastic can internalize into FLS cells;•Microplastic promoted the proliferation of RA-FLS cells;•Microplastic aggravated the pathological changes of…”
Get full text

Histone methyltransferase EZH2 in proliferation, invasion, and migration of fibroblast-like synoviocytes in rheumatoid arthritis by Chang, Lihua, Zhou, Renyi

“…Objective Rheumatoid arthritis (RA) may lead to irreversible joint damage. The role of histone modifications in RA has been emphasized. This study investigated…”
Get full text

LncRNA FOXD3-AS1 promotes breast cancer progression by mediating ARF6 by Zhang, Xingxing, Zhao, Xiaojun, Chang, Lihua, Liu, Fang, Li, Chunjuan, Ge, Peng

“…Background Breast cancer is one of the most common malignant tumor in women. The high metastatic characteristics cause a high mortality rate of breast cancer…”
Get full text

Visual analysis of the research frontiers, hotspots and trends of exercise therapy intervention in tumor-related sleep-wake disorders by Han, Jilei, Zhang, Jiachen, Zhang, Litao, Guo, Juan, Peng, Xitao, Ying, Chenlin, Li, Zhiqing, Li, Mu, Chang, Lihua, Zhang, Yani

“…To systematically understand the research frontiers, hotspots and development trends of exercise therapy in the intervention of tumor-related sleep-wake…”
Get full text

Sparstolonin B Exerts Therapeutic Effects on Collagen-Induced Arthritis by Inhibiting the NLRP3 Inflammasome and Reducing the Activity of α1,3-Fucosyltransferase by Sun, Yue, Guo, Yun, Zhang, Jing, Chang, Lihua, Zhao, Haiyan, Wang, Xiaofei

“…Objective. To explore the role of α1,3-fucosyltransferase in the mediation of rheumatoid arthritic inflammation, the protective effect of Sparstolonin B on…”
Get full text

Inhibition of microRNA-448 suppresses CD4+ T cell inflammatory activation via up-regulating suppressor of cytokine signaling 5 in systemic lupus erythematosus by Zhang, Jing, Guo, Yun, Sun, Yue, Chang, Lihua, Wang, Xiaofei

“…Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. MicroRNA-448 (miR-448) has a pro-inflammatory effect in various inflammation-related…”
Get full text

Long noncoding RNA H19 synergizes with STAT1 to regulate SNX10 in rheumatoid arthritis by Sun, Yue, Guo, Yun, Chang, Lihua, Zhang, Jing

“…Erosive destruction of joint structures is an important event in the rheumatoid arthritis (RA) development where fibroblast-like synoviocytes (FLS) represent…”
Get full text

Mesenchymal Stem Cell-Originated Exosomal Circular RNA circFBXW7 Attenuates Cell Proliferation, Migration and Inflammation of Fibroblast-Like Synoviocytes by Targeting miR-216a-3p/HDAC4 in Rheumatoid Arthritis by Chang, Lihua, Kan, Liang

“…Rheumatoid arthritis (RA) is a chronic autoimmune disease of articular joint damage and elevated synovial hyperplasia. Abnormal proliferation, invasion…”
Get full text

Disabled‐2 overexpression mediates immune suppression in systemic lupus erythematosus by modulating Treg/Th17 cell differentiation by Zhang, Jing, Chang, Lihua, Sun, Yue, Qin, Muting, Wang, Xiaofei, Guo, Yun

“…Systemic lupus erythematosus (SLE) is an autoimmune disorder. T helper 17 (Th17) and regulatory T (Treg) cells play key roles in SLE progression. Disabled‐2…”
Get full text

Quercetin ameliorates salivary gland apoptosis and inflammation in primary Sjögren's syndrome through regulation of the leptin/OB‐R signaling by Chang, Lihua, Kong, Aibin, Guo, Yun, Zhang, Jing, Sun, Yue, Chen, Penglu, Wang, Xiaofei

“…Dry mouth is the main manifestation of Sjögren syndrome (SS). Quercetin has been reported to alleviate radiation‐induced salivary gland damage, yet the effect…”
Get full text

Laser Beam Homogenization Technology and its Application in High Speed Photography by Xincai, Zhao, Weifeng, Wen, Lihua, Chang, Peng, Gao, Maojie, Ran, Jian, Li, Ningwen, Liu

“…We proposed a method of laser beam homogenization based on diffractive optical components. Applications in experiments show that the homogenization system…”
Get full text

IMPACT OF PORT OPERATION ON URBAN LOW-CARBON DEVELOPMENT by Chang, Wenqian, Zhang, Lihua, Li, Nan

“…The impact of port on city involves many aspects, including low-carbon development (LCD). This study mainly explores the role of port operation (PO) on urban…”
Get full text

miR-99a and -99b inhibit cervical cancer cell proliferation and invasion by targeting mTOR signaling pathway by Wang, Li, Chang, Lihua, Li, Zhaorong, Gao, Qing, Cai, Dongge, Tian, Yingfang, Zeng, Lingxia, Li, Mu

“…MicroRNAs were demonstrated to play an important role in the regulation of gene expression. Here, we showed that miR-99a and -99b (miR-99a/b) were…”
Get full text

Matrine exerts antitumor activity in cervical cancer by protective autophagy via the Akt/mTOR pathway in vitro and in vivo by Zhang, Fan, Zhang, Hua, Qian, Wenjun, Xi, Yuyan, Chang, Lihua, Wu, Xiaoling, Li, Mu

“…Matrine is a quinazoline alkaloid extracted from Sophora flavescens. The aim of the present study was to determine whether matrine can induce autophagy in the…”
Get full text

MicroRNA-142-5p promotes the proliferation and metastasis of nasopharyngeal carcinoma by Huang, Shujuan, Ma, Guang, Wang, Rufeng, Wang, Ning, Cui, Lijun, Chang, Lihua, Cui, Maoxiang

“…Growing pieces of evidence reported abnormal expression of microRNA in various cancer. Our research aimed to ascertain the miR-142-5p expression and its…”
Get full text

Matrine exerts antitumor activity in cervical cancer by protective autophagy via the Akt/mTOR pathway in vitroand in vivo by Zhang, Fan, Zhang, Hua, Qian, Wenjun, Xi, Yuyan, Chang, Lihua, Wu, Xiaoling, Li, Mu

“…Matrine is a quinazoline alkaloid extracted from Sophora favescens. The aim of the present study was to determine whether matrine can induce autophagy in the…”
Get full text

Sparstolonin B Exerts Therapeutic Effects on Collagen-Induced Arthritis by Inhibiting the NLRP3 Inflammasome and Reducing the Activity of α 1,3-Fucosyltransferase by Sun, Yue, Guo, Yun, Zhang, Jing, Chang, Lihua, Zhao, Haiyan, Wang, Xiaofei

“…Objective. To explore the role of α 1,3-fucosyltransferase in the mediation of rheumatoid arthritic inflammation, the protective effect of Sparstolonin B on…”
Get full text

The clinical effect of aspirin combined with low-molecular-weight heparin in the treatment of severe preeclampsia and the combination's effect on pregnancy outcomes by Chang, Lihua, Liu, Yanfeng, Zhang, Xingxing, Shi, Ziyun, Ren, Duomei, Li, Xiujuan, Li, Yanchuan

“…OBJECTIVETo explore the clinical effects of aspirin combined with low-molecular-weight heparin (LMWH) in the treatment of patients with severe preeclampsia and…”
Get full text

Analysis of red blood cells’ dynamic status in a simulated blood circulation system using an ultrahigh‐speed simultaneous framing optical electronic camera by Zhang, Qiang, Li, Zeren, Zhao, Shuming, Wen, Weifeng, Chang, Lihua, Yu, Helian, Jiang, Tianlun

“…Alterations in the morphologic and mechanical properties of red blood cells (RBCs) are considered direct indicators of blood quality. Current measures of…”
Get full text

Chrome-rich clinopyroxene in orthopyroxenite from Maowu, Dabie Mountains, central China: A second record and its implications for petrogenesis by Liu, Xiaochun, Zhou, Huyun, Ma, Zhesheng, Chang, Lihua

“…A second occurrence of chrome‐rich clinopyroxene has been discovered as inclusions in orthopyroxene in orthopyroxenite from Maowu, the Dabie Mountains, Central…”
Get full text