Search Results - "Chang, Kun‐Sang"

Inhibition of Sp1 functions by its sequestration into PML nuclear bodies by Li, June, Zou, Wen-Xin, Chang, Kun-Sang

“…Promyelocytic leukemia nuclear bodies (PML NBs) are comprised of PML and a striking variety of its associated proteins. Various cellular functions have been…”
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Role of SUMO-Interacting Motif in Daxx SUMO Modification, Subnuclear Localization, and Repression of Sumoylated Transcription Factors by Lin, Ding-Yen, Huang, Yen-Sung, Jeng, Jen-Chong, Kuo, Hong-Yi, Chang, Che-Chang, Chao, Ting-Ting, Ho, Chun-Chen, Chen, Yun-Ching, Lin, Tong-Ping, Fang, Hsin-I, Hung, Chih-Chang, Suen, Ching-Shu, Hwang, Ming-Jing, Chang, Kun-Sang, Maul, Gerd G., Shih, Hsiu-Ming

“…Small ubiquitin-like modifier (SUMO) modification has emerged as an important posttranslational control of protein functions. Daxx, a transcriptional…”
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Structural and Functional Roles of Daxx SIM Phosphorylation in SUMO Paralog-Selective Binding and Apoptosis Modulation by Chang, Che-Chang, Naik, Mandar T., Huang, Yen-Sung, Jeng, Jen-Chong, Liao, Pei-Hsin, Kuo, Hong-Yi, Ho, Chun-Chen, Hsieh, Yung-Lin, Lin, Chiou-Hong, Huang, Nai-Jia, Naik, Nandita M., Kung, Camy C.-H., Lin, Shu-Yu, Chen, Ruey-Hwa, Chang, Kun-Sang, Huang, Tai-Huang, Shih, Hsiu-Ming

“…Small ubiquitin-like modifier (SUMO) conjugation and interaction are increasingly associated with various cellular processes. However, little is known about…”
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RUNX3 promoter hypermethylation is frequent in leukaemia cell lines and associated with acute myeloid leukaemia inv(16) subtype by Estécio, Marcos R. H., Maddipoti, Sirisha, Bueso‐Ramos, Carlos, DiNardo, Courtney D., Yang, Hui, Wei, Yue, Kondo, Kimie, Fang, Zhihong, Stevenson, William, Chang, Kun‐Sang, Pierce, Sherry A., Bohannan, Zachary, Borthakur, Gautam, Kantarjian, Hagop, Garcia‐Manero, Guillermo

“…Summary Correlative and functional studies support the involvement of the RUNX gene family in haematological malignancies. To elucidate the role of epigenetics…”
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Rapid and Reliable Confirmation of Acute Promyelocytic Leukemia by Immunofluorescence Staining With an Antipromyelocytic Leukemia Antibody: The M. D. Anderson Cancer Center Experience of 349 Patients by DIMOV, Nikolay D, MEDEIROS, L. Jeffrey, KANTARJIAN, Hagop M, CORTES, Jorge E, CHANG, Kun-Sang, BUESO-RAMOS, Carlos E, RAVANDI, Farhad

“…The authors evaluated the utility of immunofluorescence staining with an antipromyelocytic leukemia (anti-PML) antibody for patients with a suspected diagnosis…”
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Signal-dependent regulation of transcription by histone deacetylase 7 involves recruitment to promyelocytic leukemia protein nuclear bodies by Gao, Chengzhuo, Cheng, Xiwen, Lam, Minh, Liu, Yu, Liu, Qing, Chang, Kun-Sang, Kao, Hung-Ying

“…Promyelocytic leukemia protein (PML) nuclear bodies (NBs) are dynamic subnuclear compartments that play roles in several cellular processes, including…”
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PML regulates PER2 nuclear localization and circadian function by Miki, Takao, Xu, Zhixiang, Chen-Goodspeed, Misty, Liu, Mingguang, Van Oort-Jansen, Anita, Rea, Michael A, Zhao, Zhaoyang, Lee, Cheng Chi, Chang, Kun-Sang

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PML Colocalizes with and Stabilizes the DNA Damage Response Protein TopBP1 by Xu, Zhi-Xiang, Timanova-Atanasova, Anna, Zhao, Rui-Xun, Chang, Kun-Sang

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A Role for PML3 in Centrosome Duplication and Genome Stability by Xu, Zhi-Xiang, Zou, Wen-Xin, Lin, Pei, Chang, Kun-Sang

“…The promyelocytic leukemia gene ( PML), which is disrupted by the chromosomal translocation t(15;17) in acute promyelocytic leukemia (APL), encodes a…”
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Promyelocytic Leukemia Protein 4 Induces Apoptosis by Inhibition of Survivin Expression by Xu, Zhi-Xiang, Zhao, Rui-Xun, Ding, Tian, Tran, Thanh T., Zhang, Wei, Pandolfi, Pier Paolo, Chang, Kun-Sang

“…The promyelocytic leukemia protein (PML) plays an essential role in multiple pathways of apoptosis. Our previous study showed that PML enhances tumor necrosis…”
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The Promyelocytic Leukemia Protein Interacts with Sp1 and Inhibits Its Transactivation of the Epidermal Growth Factor Receptor Promoter by Vallian, Sadeq, Chin, Khew-Voon, Chang, Kun-Sang

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Analysis of the Growth and Transformation Suppressor Domains of Promyelocytic Leukemia Gene, PML(∗) by Le, Xiao-Feng, Yang, Peirong, Chang, Kun-Sang

“…The promyelocytic leukemia gene (PML) involved in the t(15;17) (q22;q12) translocation in acute promyelocytic leukemia is a growth suppressor. To elucidate the…”
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PML regulates PER2 nuclear localization and circadian function by Miki, Takao, Xu, Zhixiang, Chen‐Goodspeed, Misty, Liu, Mingguang, Van Oort‐Jansen, Anita, Rea, Michael A, Zhao, Zhaoyang, Lee, Cheng Chi, Chang, Kun‐Sang

“…Studies have suggested that the clock regulator PER2 is a tumour suppressor. A cancer network involving PER2 raises the possibility that some tumour…”
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Promyelocytic leukemia protein PML inhibits Nur77-mediated transcription through specific functional interactions by WU, Wen-Shu, XU, Zhi-Xiang, RUIXIANG RAN, FENG MENG, CHANG, Kun-Sang

“…The promyelocytic leukemia protein PML is a tumor and growth suppressor and plays an important role in a multiple pathways of apoptosis and regulation of cell…”
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Recombinant PML adenovirus suppresses growth and tumorigenicity of human breast cancer cells by inducing G1 cell cycle arrest and apoptosis by LE, X.-F, VALLIAN, S, MU, Z.-M, HUNG, M.-C, CHANG, K.-S

“…Our previous studies demonstrated that the promyelocytic leukemia gene, PML which involved in the 15;17 translocation in acute promyelocytic leukemia (APL) is…”
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The PML Gene Encodes a Phosphoprotein Associated With the Nuclear Matrix by Chang, Kun-Sang, Fan, You-Hong, Andreeff, Michael, Liu, Jiaxin, Mu, Zhao-Mei

“…The t(15;17)(q22;q12) translocation is the cytogenetic hallmark of acute promyelocytic leukemia (APL). The PML and retinoic acid receptor-α (RARα)…”
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Degradation of the Tumor Suppressor PML by Pin1 Contributes to the Cancer Phenotype of Breast Cancer MDA-MB-231 Cells by Reineke, Erin L., Lam, Minh, Liu, Qing, Liu, Yu, Stanya, Kristopher J., Chang, Kun-Sang, Means, Anthony R., Kao, Hung-Ying

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The Promyelocytic Leukemia Protein Represses A20-mediated Transcription by Wu, Wen-Shu, Xu, Zhi-Xiang, Chang, Kun-Sang

“…The promyelocytic leukemia (PML) protein is a tumor suppressor that is disrupted by the chromosomal translocation t(15;17), a consistent cytogenetic feature of…”
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Modulation of Fos-mediated AP-1 transcription by the promyelocytic leukemia protein by VALLIAN, S, GÄKEN, J. A, GINGOLD, E. B, KOUZARIDES, T, CHANG, K.-S, FARZANEH, F

“…The growth and transformation suppressor function of promyelocytic leukemia (PML) protein are disrupted in acute promyelocytic leukemia (APL) as a result of…”
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Detection of Minimal Residual Cells Carrying the t(14;18) by DNA Sequence Amplification by Lee, Ming-Sheng, Chang, Kun-Sang, Cabanillas, Fernando, Freireich, Emil J., Trujillo, Jose M., Stass, Sanford A.

“…By means of the polymerase chain reaction (PCR) technique, DNA sequences were amplified that flank the crossover sites of a characteristic chromosomal…”
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