Search Results - "Chang, Koping"
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Altered thalamocortical tract trajectory growth with undisrupted thalamic parcellation pattern in human lissencephaly brain at mid-gestational stage
Published in Neurobiology of disease (01-09-2024)“…Proper topographically organized neural connections between the thalamus and the cerebral cortex are mandatory for thalamus function. Thalamocortical (TC)…”
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2
Spinal chordoma and chondrosarcoma treatment experiences - a 20-year retrospective study from databases of two medical centers
Published in Scientific reports (03-10-2024)“…The research retrospectively analyzed cases of spinal chordoma and chondrosarcoma involving patients who received treatment at the two hospitals between 2001…”
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3
Unique Phenotypes With Corresponding Pathology in Late-Onset Hereditary Transthyretin Amyloidosis of A97S vs. V30M
Published in Frontiers in aging neuroscience (26-01-2022)“…Hereditary transthyretin amyloidosis (ATTRv) encompasses different phenotypes among various genotypes. The analysis of the natural history and risk factors of…”
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4
Elevated nuclear TDP-43 induces constitutive exon skipping
Published in Molecular neurodegeneration (09-06-2024)“…Cytoplasmic inclusions and loss of nuclear TDP-43 are key pathological features found in several neurodegenerative disorders, suggesting both gain- and…”
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5
Decreased CD11c‐positive dendritic cells in the tumor microenvironment predict double‐hit/triple‐hit genotype and survival in diffuse large B‐cell lymphoma
Published in The journal of pathology. Clinical research (01-09-2022)“…Diffuse large B‐cell lymphoma (DLBCL) is the most common type of non‐Hodgkin lymphoma and is a potentially curable disease. However, it is heterogenous, and…”
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6
Lactate peak in muscle disclosed by magnetic resonance spectroscopy in a patient with CPEO-plus syndrome
Published in eNeurologicalSci (01-09-2021)“…A 25-year-old man complained of progressive diplopia and limb weakness for 3 years. Mitochondrial myopathy was suspected according to clinical presentation,…”
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7
Lateral geniculate body is spared of tau pathology in Pick disease
Published in Journal of neuropathology and experimental neurology (20-03-2024)“…Abstract The pathobiology of tau is of great importance for understanding the mechanisms of neurodegeneration in aging and age-associated disorders such as…”
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8
Temporal lobe uncal herniation with contralateral superior cerebellar artery infarct
Published in Journal of forensic sciences (01-01-2024)“…Herniation of the temporal lobe uncus typically leads to the compression of the ipsilateral oculomotor nerve, resulting in ipsilateral mydriasis, as well as…”
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9
Mechanisms of COVID‐19‐associated olfactory dysfunction
Published in Neuropathology and applied neurobiology (01-04-2024)“…Olfactory dysfunction is one of the most common symptoms of COVID‐19. In the first 2 years of the pandemic, it was frequently reported, although its incidence…”
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10
A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS–FTD
Published in Nature medicine (01-02-2024)“…Although loss of TAR DNA-binding protein 43 kDa (TDP-43) splicing repression is well documented in postmortem tissues of amyotrophic lateral sclerosis (ALS)…”
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Loss of TDP-43 splicing repression occurs early in the aging population and is associated with Alzheimer’s disease neuropathologic changes and cognitive decline
Published in Acta neuropathologica (01-06-2024)“…LATE-NC, the neuropathologic changes of limbic-predominant age-related TAR DNA-binding protein 43 kDa (TDP-43) encephalopathy are frequently associated with…”
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12
Skin keratinocyte-derived SIRT1 and BDNF modulate mechanical allodynia in mouse models of diabetic neuropathy
Published in Brain (London, England : 1878) (03-10-2024)“…Diabetic neuropathy is a debilitating disorder characterized by spontaneous and mechanical allodynia. The role of skin mechanoreceptors in the development of…”
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13
Head and Neck Mesenchymal Neoplasms With GLI1 Gene Alterations: A Pathologic Entity With Distinct Histologic Features and Potential for Distant Metastasis
Published in The American journal of surgical pathology (01-06-2020)“…Soft tissue tumors with GLI1 gene fusions or amplifications have been recently described as a unique pathologic entity with an established risk of malignancy…”
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Outcomes of extended progestin therapy in atypical endometrial hyperplasia patients without an initial response to progestin: a retrospective study from two tertiary centers in Korea and Taiwan
Published in Journal of gynecologic oncology (08-07-2024)“…In this study, we evaluated the role of prolonged progestin treatment on atypical endometrial hyperplasia (AEH) patients who did not achieve complete…”
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15
Impact of adjuvant treatment on survival in patients with 2023 FIGO stage IIC endometrial cancer: a retrospective analysis from two tertiary centers in Korea and Taiwan
Published in Journal of gynecologic oncology (01-05-2024)“…In early-stage endometrial cancer, aggressive histologic types (grade 3 endometrioid, serous, clear cell, carcinosarcomas, undifferentiated, mixed, and other…”
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Pure LATE-NC: Frequency, clinical impact, and the importance of considering APOE genotype when assessing this and other subtypes of non-Alzheimer’s pathologies
Published in Acta neuropathologica (15-11-2024)“…Pure limbic-predominant age-related TDP-43 encephalopathy neuropathologic changes (pure LATE-NC) is a term used to describe brains with LATE-NC but lacking…”
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A phase Ib/II study of the combination of lenvatinib (L) and eribulin (E) in advanced liposarcoma (LPS) and leiomyosarcoma (LMS) (LEADER): Efficacy updates
Published in Journal of clinical oncology (01-06-2022)“…11506 Background: There are limited treatment options for advanced LPS and LMS, the two most common histologies in soft tissue sarcoma. Patients (pts) treated…”
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A Single-Arm Phase Ib/II Study of Lenvatinib plus Eribulin in Advanced Liposarcoma and Leiomyosarcoma
Published in Clinical cancer research (01-12-2022)“…Satisfactory treatment options for advanced leiomyosarcoma and liposarcoma are limited. The LEADER study (NCT03526679) investigated the safety and efficacy of…”
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Author Correction: A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS–FTD
Published in Nature medicine (01-05-2024)Get full text
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20
Does para-aortic lymphadenectomy improve survival in pathologically diagnosed early-stage grade 3 endometrioid and non-endometrioid endometrial cancers? A retrospective cohort study in Korea and Taiwan
Published in Gynecologic oncology (01-10-2022)“…PURPOSEThe therapeutic effect of para-aortic lymphadenectomy in early-stage high-grade endometrial cancer remains controversial. In this study, we investigated…”
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