Search Results - "Chang, Kevin Y."

Mortality in Pulmonary Arterial Hypertension in the Modern Era: Early Insights From the Pulmonary Hypertension Association Registry by Chang, Kevin Y, Duval, Sue, Badesch, David B, Bull, Todd M, Chakinala, Murali M, De Marco, Teresa, Frantz, Robert P, Hemnes, Anna, Mathai, Stephen C, Rosenzweig, Erika Berman, Ryan, John J, Thenappan, Thenappan

“…Background Current mortality data for pulmonary arterial hypertension (PAH) in the United States are based on registries that enrolled patients prior to 2010…”
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Bleeding and Thrombosis in Patients With Out-of-Hospital Ventricular Tachycardia/Ventricular Fibrillation Arrest Treated With Extracorporeal Cardiopulmonary Resuscitation by Gutierrez, Alejandra, Kalra, Rajat, Chang, Kevin Y, Steiner, Marie E, Marquez, Alexandra M, Alexy, Tamas, Elliott, Andrea M, Nowariak, Meagan, Yannopoulos, Demetris, Bartos, Jason A

“…Extracorporeal cardiopulmonary resuscitation improves outcomes after out-of-hospital cardiac arrest. However, bleeding and thrombosis are common complications…”
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Effect of Chronic Digoxin Use on Mortality and Heart Failure Hospitalization in Pulmonary Arterial Hypertension by Chang, Kevin Y, Giorgio, Katherine, Schmitz, Katlin, Walker, Rob F, Prins, Kurt W, Pritzker, Marc R, Archer, Stephen L, Lutsey, Pamela L, Thenappan, Thenappan

“…Background Digoxin acutely increases cardiac output in patients with pulmonary arterial hypertension (PAH) and right ventricular failure; however, the effects…”
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Spinal Biologics in Minimally Invasive Lumbar Surgery by Chang, Kevin Y., Hsu, Wellington

“…As the use of minimally invasive spine (MIS) fusion approaches continues to grow, increased scrutiny is being placed on its outcomes and efficacies against…”
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Intratracheal instillation of pravastatin for the treatment of murine allergic asthma: a lung‐targeted approach to deliver statins by Zeki, Amir A., Bratt, Jennifer M., Chang, Kevin Y., Franzi, Lisa M., Ott, Sean, Silveria, Mark, Fiehn, Oliver, Last, Jerold A., Kenyon, Nicholas J.

“…Systemic treatment with statins mitigates allergic airway inflammation, TH2 cytokine production, epithelial mucus production, and airway hyperreactivity (AHR)…”
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Pericardial Manifestations of Thyroid Diseases by Chahine, Johnny, Jedeon, Zeina, Chang, Kevin Y., Jellis, Christine L.

“…Purpose of Review Thyroid disorders, especially hypothyroidism, are known to be associated with pericardial diseases. The aim of this paper is to review the…”
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Effect of Postoperative Analgesic Exposure to the Cannabinoid Receptor Agonist WIN55 on Osteogenic Differentiation and Spinal Fusion in Rats by Yun, Chawon, Haleem, Meraaj S., Jeong, Soyeon, Oyer, Mark A., Driscoll, Adam J., Chang, Kevin Y., Yun, Jonghwa, Paul, Jonathan, Lubbe, Ryan J., Stock, Stuart R., Hsu, Wellington K., Hsu, Erin L.

“…After spinal surgery and other orthopaedic procedures, most patients receive opioids for pain, leading to potential complications such as pseudarthrosis and…”
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Impact of Loop Diuretic Use on Outcomes Following Transcatheter Aortic Valve Implantation by Cantey, Eric P., Chang, Kevin Y., Blair, John E.A., Brummel, Kent, Sweis, Ranya N., Pham, Duc T., Adi, Adin-Christian, Churyla, Andrei, Ricciardi, Mark J., Malaisrie, S. Chris, Davidson, Charles J., Flaherty, James D.

“…•Severe AS is characterized by chronic pressure overload and impairment in left ventricular remodeling.•Loop-diuretic therapy prior to TAVI is a marker of…”
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Farnesyltransferase Inhibition Exacerbates Eosinophilic Inflammation and Airway Hyperreactivity in Mice with Experimental Asthma: The Complex Roles of Ras GTPase and Farnesylpyrophosphate in Type 2 Allergic Inflammation by Bratt, Jennifer M, Chang, Kevin Y, Rabowsky, Michelle, Franzi, Lisa M, Ott, Sean P, Filosto, Simone, Goldkorn, Tzipora, Arif, Muhammad, Last, Jerold A, Kenyon, Nicholas J, Zeki, Amir A

“…Ras, a small GTPase protein, is thought to mediate Th2-dependent eosinophilic inflammation in asthma. Ras requires cell membrane association for its biological…”
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Effect of Postoperative Analgesic Exposure to the Cannabinoid Receptor Agonist WIN55 on Osteogenic Differentiation and Spinal Fusion in Rats by Yun, Chawon, Haleem, Meraaj S., Jeong, Soyeon, Oyer, Mark A., Driscoll, Adam J., Chang, Kevin Y., Yun, Jonghwa, Paul, Jonathan, Lubbe, Ryan J., Stock, Stuart R., Hsu, Wellington K., Hsu, Erin L.

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Spinal Biologies in Minimally Invasive Lumbar Surgery by Chang, Kevin Y, Hsu, Wellington K

“…As the use of minimally invasive spine (MIS) fusion approaches continues to grow, increased scrutiny is beingplaced on its outcomes and efficacies against…”
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Thursday, September 27, 2018 2:05 PM–3:05 PM Section on Biologics and Basic Research Abstract Presentations by Jeong, Soyeon, Yun, Chawon, Driscoll, John A., Chang, Kevin Y., Haleem, Meraaj S., Lubbe, Ryan, Pahapill, Richard R., Hsu, Wellington K., Hsu, Erin L.

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Friday, September 28, 2018 4:05 PM–5:05 PM abstracts: basic science of spinal fusion by Yun, Chawon, Driscoll, John A., Chang, Kevin Y., Haleem, Meraaj S., Jeong, Soyeon, Lubbe, Ryan, Pahapill, Richard R., Hsu, Wellington K., Hsu, Erin L.

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Thursday, September 27, 2018 2:05 PM–3:05 PM Section on Biologics and Basic Research Abstract Presentations: 127. Peptide amphiphiles nanofiber scaffolds promote spine fusion in rats treated with particulate phase extract by Jeong, Soyeon, Yun, Chawon, Driscoll, John A., Chang, Kevin Y., Haleem, Meraaj S., Lubbe, Ryan, Pahapill, Richard R., Hsu, Wellington K., Hsu, Erin L.

“…Cigarette smoking is significant risk factor for the development of nonunion following spine fusion. Smoking cessation alone does not mitigate this increase in…”
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Friday, September 28, 2018 4:05 PM–5:05 PM abstracts: basic science of spinal fusion: 237. Effect of a systemic postoperative cannabinoid receptor agonist on spine fusion in rat model by Yun, Chawon, Driscoll, John A., Chang, Kevin Y., Haleem, Meraaj S., Jeong, Soyeon, Lubbe, Ryan, Pahapill, Richard R., Hsu, Wellington K., Hsu, Erin L.

“…Following spine surgery, most patients receive opioid medication for analgesia. Opioids have caused controversy in popular culture because of frequent overuse…”
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Friday, September 28, 2018 4:05 PM–5:05 PM abstracts: basic science of spinal fusion: 236. Composition of hyperelastic bone composite scaffolds affects de novo bone formation by Lubbe, Ryan, Jakus, Adam E., Driscoll, John A., Chang, Kevin Y., Haleem, Meraaj S., Yun, Chawon, Jeong, Soyeon, Li, Xin, Yun, Jonghwa, Baker, Kevin, Stock, Stuart R., Shah, Ramille N., Hsu, Wellington K., Hsu, Erin L.

“…Bone graft extenders for spine fusion include demineralized bone matrix (DBM) and ceramic-based products, but their efficacy is insufficient to qualify them as…”
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Friday, September 28, 2018 4:05 PM–5:05 PM abstracts: basic science of spinal fusion by Lubbe, Ryan, Jakus, Adam E., Driscoll, John A., Chang, Kevin Y., Haleem, Meraaj S., Yun, Chawon, Jeong, Soyeon, Li, Xin, Yun, Jonghwa, Baker, Kevin, Stock, Stuart R., Shah, Ramille N., Hsu, Wellington K., Hsu, Erin L.

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Friday, September 28, 2018 4:05 PM–5:05 PM abstracts: basic science of spinal fusion: 239. Architectural and geometric considerations in the development of a 3D-printed hyperelastic "Bone" composite scaffold as bone graft substitute for spinal arthrodesis by Jakus, Adam E., Haleem, Meraaj S., Driscoll, John A., Chang, Kevin Y., Lubbe, Ryan, Pahapill, Richard R., Jeong, Soyeon, Yun, Chawon, Stock, Stuart R., Shah, Ramille N., Hsu, Wellington K., Hsu, Erin L.

“…Pseudarthrosis occurs in 10%-15% of patients undergoing spine fusion. We have previously developed a unique, recombinant growth factor-free bone graft…”
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Friday, September 28, 2018 4:05 PM–5:05 PM abstracts: basic science of spinal fusion by Jeong, Soyeon, Yun, Chawon, Yun, Jonghwa, Pahapill, Richard R., Lubbe, Ryan, Driscoll, John A., Chang, Kevin Y., Haleem, Meraaj S., Cho, Minho, Kotamathi, Janavi, Hsu, Wellington K., Hsu, Erin L.

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Friday, September 28, 2018 4:05 PM–5:05 PM abstracts: basic science of spinal fusion: 235. Peptide amphiphile nanoscaffolds potentiates the delivery of rh-BMP2 in a rabbit spine fusion model by Chang, Kevin Y., McClendon, Mark, Driscoll, John A., Lubbe, Ryan, Haleem, Meraaj S., Yun, Chawon, Pahapill, Richard R., Stock, Stuart R., Stupp, Samuel I., Hsu, Erin L., Hsu, Wellington K.

“…Recombinant human bone morphogenetic protein (rhBMP-2) is an effective biologic to mitigate pseudoarthrosis after spinal fusion surgery. However,…”
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