Search Results - "Chang, Hsin‐wen"
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Influence of diet on the gut microbiome and implications for human health
Published in Journal of translational medicine (08-04-2017)“…Recent studies have suggested that the intestinal microbiome plays an important role in modulating risk of several chronic diseases, including inflammatory…”
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Empirical likelihood‐based inference for functional means with application to wearable device data
Published in Journal of the Royal Statistical Society. Series B, Statistical methodology (01-11-2022)“…This paper develops a nonparametric inference framework that is applicable to occupation time curves derived from wearable device data. These curves consider…”
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3
Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization
Published in Microbiome (05-09-2018)“…Psoriasis impacts 1-3% of the world's population and is characterized by hyper-proliferation of keratinocytes and increased inflammation. At the molecular…”
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Single-cell RNA sequencing of psoriatic skin identifies pathogenic Tc17 cell subsets and reveals distinctions between CD8+ T cells in autoimmunity and cancer
Published in Journal of allergy and clinical immunology (01-06-2021)“…Psoriasis is an inflammatory, IL-17–driven skin disease in which autoantigen-induced CD8+ T cells have been identified as pathogenic drivers. Our study focused…”
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5
Early-life exposure to polycyclic aromatic hydrocarbons and ADHD behavior problems
Published in PloS one (05-11-2014)“…Polycyclic aromatic hydrocarbons are widespread urban air pollutants from combustion of fossil fuel and other organic material shown previously to be…”
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6
Women's Reasons for Leaving the Engineering Field
Published in Frontiers in psychology (30-06-2017)“…Among the different Science, Technology, Engineering, and Math fields, engineering continues to have one of the highest rates of attrition (Hewlett et al.,…”
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7
Beyond the Debye length in high ionic strength solution: direct protein detection with field-effect transistors (FETs) in human serum
Published in Scientific reports (12-07-2017)“…In this study, a new type of field-effect transistor (FET)-based biosensor is demonstrated to be able to overcome the problem of severe charge-screening effect…”
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8
Bivariate Analysis of Distribution Functions Under Biased Sampling
Published in The American statistician (02-04-2024)“…This article compares distribution functions among pairs of locations in their domains, in contrast to the typical approach of univariate comparison across…”
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9
Inference for the dimension of a regression relationship using pseudo-covariates
Published in Biometrics (01-09-2023)“…In data analysis using dimension reduction methods, the main goal is to summarize how the response is related to the covariates through a few linear…”
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10
Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity in Caenorhabditis elegans
Published in Proceedings of the National Academy of Sciences - PNAS (21-10-2014)“…Significance Reactive oxygen species (ROS) have long been thought to cause aging and considered to be toxic byproducts generated during mitochondrial…”
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11
Large-Scale 1T′-Phase Tungsten Disulfide Atomic Layers Grown by Gas-Source Chemical Vapor Deposition
Published in ACS nano (23-08-2022)“…The control of crystal polymorphism and exploration of metastable, two-dimensional, 1T′-phase, transition-metal dichalcogenides (TMDs) have received…”
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Long noncoding RNA TUG1 is downregulated in non-small cell lung cancer and can regulate CELF1 on binding to PRC2
Published in BMC cancer (02-08-2016)“…Long noncoding RNAs (lncRNAs) play crucial roles in tumorigenesis, and lncRNA taurine-upregulated gene 1 (TUG1) has been proven to be associated with several…”
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13
RNA-seq and flow-cytometry of conventional, scalp, and palmoplantar psoriasis reveal shared and distinct molecular pathways
Published in Scientific reports (27-07-2018)“…It has long been recognized that anatomic location is an important feature for defining distinct subtypes of plaque psoriasis. However, little is known about…”
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14
Digital quantification of DNA via isothermal amplification on a self-driven microfluidic chip featuring hydrophilic film-coated polydimethylsiloxane
Published in Biosensors & bioelectronics (15-01-2018)“…Loop-mediated isothermal amplification (LAMP) is a DNA amplification approach characterized by high sensitivity and specificity. In “digital LAMP”, small…”
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15
MTAP deficiency contributes to immune landscape remodelling and tumour evasion
Published in Immunology (01-02-2023)“…Methylthioadenosine phosphorylase (MTAP) deficiency occurs in various malignancies and is associated with poor survival in cancer patients. However, the…”
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Gate-First High-Performance Germanium nMOSFET and pMOSFET Using Low Thermal Budget Ion Implantation After Germanidation Technique
Published in IEEE electron device letters (01-03-2016)“…The fabrication of high-performance Ge nMOSFET and pMOSFET by using the ion implantation after germanidation (IAG) technique is demonstrated. TaN/Al 2 O 3 /GeO…”
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Transcription factors CEP‐1/p53 and CEH‐23 collaborate with AAK‐2/AMPK to modulate longevity in Caenorhabditis elegans
Published in Aging cell (01-08-2017)“…Summary A decline in mitochondrial electron transport chain (ETC) function has long been implicated in aging and various diseases. Recently, moderate…”
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Molecular Modeling of ALK L1198F and/or G1202R Mutations to Determine Differential Crizotinib Sensitivity
Published in Scientific reports (06-08-2019)“…Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase that has been recognized as a therapeutic target for EML4-ALK fusion-positive nonsmall cell lung…”
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Reduced symmetric dimethylation stabilizes vimentin and promotes metastasis in MTAP‐deficient lung cancer
Published in EMBO reports (03-08-2022)“…The aggressive nature and poor prognosis of lung cancer led us to explore the mechanisms driving disease progression. Utilizing our invasive cell‐based model,…”
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The Role of the Skin and Gut Microbiome in Psoriatic Disease
Published in Current dermatology reports (01-06-2017)“…Purpose of Review To understand the changes in the microbiome in psoriatic disease, we conducted a systematic review of studies comparing the skin and gut…”
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