Search Results - "Chang, Gwo‐Jyh"
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miR-181b targets semaphorin 3A to mediate TGF-β–induced endothelial-mesenchymal transition related to atrial fibrillation
Published in The Journal of clinical investigation (01-07-2022)“…Atrial fibrosis is an essential contributor to atrial fibrillation (AF). It remains unclear whether atrial endocardial endothelial cells (AEECs) that undergo…”
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2
Platelet-Rich Plasma Releasate Promotes Regeneration and Decreases Inflammation and Apoptosis of Injured Skeletal Muscle
Published in The American journal of sports medicine (01-07-2018)“…Background: Platelet-rich plasma (PRP) contains various cytokines and growth factors that may be beneficial to the healing process of injured muscle. Based on…”
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3
Naringin activates semaphorin 3A to ameliorate TGF‐β‐induced endothelial‐to‐mesenchymal transition related to atrial fibrillation
Published in Journal of cellular physiology (01-05-2024)“…The loss of semaphorin 3A (Sema3A), which is related to endothelial‐to‐mesenchymal transition (EndMT) in atrial fibrosis, is implicated in the pathogenesis of…”
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4
Atrial fibrillation and its arrhythmogenesis associated with insulin resistance
Published in Cardiovascular diabetology (26-09-2019)“…Insulin resistance (IR) is considered as a risk factor for atrial fibrillation (AF) even before diabetes develops. The pathophysiology and underlying mechanism…”
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5
Hemodynamic and electromechanical effects of paraquat in rat heart
Published in PloS one (01-04-2021)“…Paraquat (PQ) is a highly lethal herbicide. Ingestion of large quantities of PQ usually results in cardiovascular collapse and eventual mortality. Recent…”
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6
High‐phosphate diet causes atrial remodeling and increases atrial fibrillation vulnerability via STAT3/NF‐κB signaling and oxidative stress
Published in Acta Physiologica (01-06-2023)“…Aim Hyperphosphatemia is associated with adverse cardiovascular outcomes in both the general population and patients with end‐stage renal disease. We evaluated…”
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7
Selective SERCA2a activator as a candidate for chronic heart failure therapy
Published in Journal of translational medicine (19-01-2024)“…The sarcoplasmic reticulum (SR) Ca ATPase (SERCA2a) depression substantially contributes to diastolic dysfunction in heart failure (HF), suggesting that…”
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Aldehyde Dehydrogenase 2 (ALDH2) Deficiency, Obesity, and Atrial Fibrillation Susceptibility: Unraveling the Connection
Published in International journal of molecular sciences (01-02-2024)“…Atrial fibrillation (AF), characterized by structural remodeling involving atrial myocardial degradation and fibrosis, is linked with obesity and transforming…”
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Use of Platelet-Rich Plasma Plus Suramin, an Antifibrotic Agent, to Improve Muscle Healing After Injuries
Published in The American journal of sports medicine (01-09-2021)“…Background: The increasing use of platelet-rich plasma (PRP) to treat muscle injuries raises concerns because transforming growth factor–beta (TGF-β) in PRP…”
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10
Candesartan Cilexetil Attenuates Arrhythmogenicity Following Pressure Overload in Rats via the Modulation of Cardiac Electrical and Structural Remodeling and Calcium Handling Dysfunction
Published in Journal of the American Heart Association (02-08-2022)“…Background Cardiac hypertrophy is associated with abnormal electrophysiology and increased arrhythmia risk. This study assessed whether candesartan cilexetil,…”
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11
A Novel KCNH2 S981fs Mutation Identified by Whole-Exome Sequencing Is Associated with Type 2 Long QT Syndrome
Published in International journal of molecular sciences (13-08-2023)“…KCNH2 loss-of-function mutations cause long QT syndrome type 2 (LQT2), an inherited cardiac disorder associated with life-threatening ventricular arrhythmia…”
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12
Differential left-to-right atria gene expression ratio in human sinus rhythm and atrial fibrillation: Implications for arrhythmogenesis and thrombogenesis
Published in International journal of cardiology (01-11-2016)“…Abstract Background Atrial fibrillation (AF) causes atrial remodeling, and the left atrium (LA) is the favored substrate for maintaining AF. It remains unclear…”
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13
Aldehyde Dehydrogenase 2 Ameliorates Chronic Alcohol Consumption-Induced Atrial Fibrillation through Detoxification of 4-HNE
Published in International journal of molecular sciences (12-09-2020)“…Aldehyde dehydrogenase 2 (ALDH2) is an enzyme that detoxifies reactive oxygen species (ROS)-generated aldehyde adducts such as 4-hydroxy-trans-2-nonenal…”
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14
The Effect of Hyperbaric Oxygen Treatment on Myoblasts and Muscles After Contusion Injury
Published in Journal of orthopaedic research (01-02-2020)“…ABSTRACT The recommended treatment varies depending on the severity of muscle injuries. The aim of this study was to evaluate the in vitro myoblast…”
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15
Ethyl pyruvate attenuates ventilation‐induced diaphragm dysfunction through high‐mobility group box‐1 in a murine endotoxaemia model
Published in Journal of cellular and molecular medicine (01-08-2019)“…Mechanical ventilation (MV) can save the lives of patients with sepsis. However, MV in both animal and human studies has resulted in ventilator‐induced…”
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16
Ubiquitin Pathway Is Associated with Worsening Left Ventricle Function after Mitral Valve Repair: A Global Gene Expression Study
Published in International journal of molecular sciences (18-07-2020)“…The molecular mechanism for worsening left ventricular (LV) function after mitral valve (MV) repair for chronic mitral regurgitation remains unknown. We wished…”
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17
Inhomogeneous downregulation of I Na underlies piceatannol proarrhythmic mechanism in regional ischemia-reperfusion
Published in Pacing and clinical electrophysiology (01-09-2018)“…Piceatannol, a grape-derived polyphenol, has been linked to proarrhythmic properties by aggravating inhomogeneous conduction delay in the ischemia-reperfusion…”
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18
Inhomogeneous downregulation of INa underlies piceatannol proarrhythmic mechanism in regional ischemia‐reperfusion
Published in Pacing and clinical electrophysiology (01-09-2018)“…Background Piceatannol, a grape‐derived polyphenol, has been linked to proarrhythmic properties by aggravating inhomogeneous conduction delay in the…”
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19
Pleomorphic mantle cell lymphoma morphologically mimicking diffuse large B cell lymphoma: common cyclin D1 negativity and a simple immunohistochemical algorithm to avoid the diagnostic pitfall
Published in Histopathology (01-05-2017)“…Aims To characterize the clinicopathological and genetic features of pleomorphic mantle cell lymphoma (PMCL), which morphologically mimics diffuse large B cell…”
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20
Propylthiouracil Attenuates Experimental Pulmonary Hypertension via Suppression of Pen-2, a Key Component of Gamma-Secretase
Published in PloS one (14-09-2015)“…Gamma-secretase-mediated Notch3 signaling is involved in smooth muscle cell (SMC) hyper-activity and proliferation leading to pulmonary arterial hypertension…”
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