Search Results - "Chang, Geen‐Dong"

Promotion of homology-directed DNA repair by polyamines by Lee, Chih-Ying, Su, Guan-Chin, Huang, Wen-Yen, Ko, Min-Yu, Yeh, Hsin-Yi, Chang, Geen-Dong, Lin, Sung-Jan, Chi, Peter

“…Polyamines, often elevated in cancer cells, have been shown to promote cell growth and proliferation. Whether polyamines regulate other cell functions remains…”
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Quantitative display of the redox status of proteins with maleimide‐polyethylene glycol tagging by Lee, Yu‐Jung, Chang, Geen‐Dong

“…Cysteine oxidation, either biologically reversible or irreversible, is the main posttranslational modification associated with redox signaling and oxidative…”
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Functional antagonism between ΔNp63α and GCM1 regulates human trophoblast stemness and differentiation by Wang, Liang-Jie, Chen, Chie-Pein, Lee, Yun-Shien, Ng, Pui-Sze, Chang, Geen-Dong, Pao, Yu-Hsuan, Lo, Hsiao-Fan, Peng, Chao-Hsiang, Cheong, Mei-Leng, Chen, Hungwen

“…The combination of EGF, CHIR99021, A83-01, SB431542, VPA, and Y27632 (EGF/CASVY) facilitates the derivation of trophoblast stem (TS) cells from human…”
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PTPN3 suppresses lung cancer cell invasiveness by counteracting Src-mediated DAAM1 activation and actin polymerization by Li, Meng-Yen, Peng, Wen-Hsin, Wu, Chien-Hsun, Chang, Ya-Min, Lin, Yu-Ling, Chang, Geen-Dong, Wu, Han-Chung, Chen, Guang-Chao

“…Cancer cell migration plays a crucial role during the metastatic process. Reversible tyrosine phosphorylation by protein tyrosine kinases (PTKs) and protein…”
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White Spot Syndrome Virus Induces Metabolic Changes Resembling the Warburg Effect in Shrimp Hemocytes in the Early Stage of Infection by CHEN, I-Tung, AOKI, Takashi, HUANG, Yun-Tzu, HIRONO, Ikuo, CHEN, Tsan-Chi, HUANG, Jiun-Yan, CHANG, Geen-Dong, LO, Chu-Fang, WANG, Han-Ching

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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An invertebrate Warburg effect: a shrimp virus achieves successful replication by altering the host metabolome via the PI3K-Akt-mTOR pathway by Su, Mei-An, Huang, Yun-Tzu, Chen, I-Tung, Lee, Der-Yen, Hsieh, Yun-Chieh, Li, Chun-Yuan, Ng, Tze Hann, Liang, Suh-Yuen, Lin, Shu-Yu, Huang, Shiao-Wei, Chiang, Yi-An, Yu, Hon-Tsen, Khoo, Kay-Hooi, Chang, Geen-Dong, Lo, Chu-Fang, Wang, Han-Ching

“…In this study, we used a systems biology approach to investigate changes in the proteome and metabolome of shrimp hemocytes infected by the invertebrate virus…”
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Afatinib Exerts Immunomodulatory Effects by Targeting the Pyrimidine Biosynthesis Enzyme CAD by Tu, Hsin-Fang, Ko, Chun-Jung, Lee, Ching-Tai, Lee, Cheng-Fan, Lan, Shao-Wei, Lin, Hsin-Hsien, Lin, Hsin-Ying, Ku, Chia-Chi, Lee, Der-Yen, Chen, I-Chun, Chuang, Ya-Hui, Del Caño-Ochoa, Francisco, Ramón-Maiques, Santiago, Ho, Chao-Chi, Lee, Ming-Shyue, Chang, Geen-Dong

“…Current clinical trials of combined EGFR-tyrosine kinase inhibitors (TKI) and immune checkpoint blockade (ICB) therapies show no additional effect. This raises…”
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Potential role of follicle-stimulating hormone (FSH) and transforming growth factor (TGFβ1) in the regulation of ovarian angiogenesis by Kuo, Shih-Wei, Ke, Ferng-Chun, Chang, Geen-Dong, Lee, Ming-Ting, Hwang, Jiuan-Jiuan

“…Angiogenesis occurs during ovarian follicle development and luteinization. Pituitary secreted FSH was reported to stimulate the expression of endothelial…”
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The study of isotopic enrichment of water in human plasma and erythrocyte by Lin, Yuan‐Hau, Wang, Ying‐Chi, Wu, Mai‐Szu, Lu, Kuo‐Cheng, Lin, Hsin‐Yi, Kuo, Hsien‐Shou, Chang, Geen‐Dong, Lin, Chun‐Mao, Hsiao, Chiaolong

“…Life does not sustain without water. For water, there is a natural abundance of stable isotope hydrogen and oxygen. Water molecules get across cell membranes…”
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Dietary flavonoids, luteolin and quercetin, inhibit invasion of cervical cancer by reduction of UBE2S through epithelial-mesenchymal transition signaling by Lin, Tsung-Han, Hsu, Wen-Hsien, Tsai, Pei-Hsun, Huang, Ying-Tang, Lin, Cheng-Wei, Chen, Ku-Chung, Tsai, Inn-Ho, Kandaswami, Chithan C, Huang, Chang-Jen, Chang, Geen-Dong, Lee, Ming-Ting, Cheng, Chia-Hsiung

“…We previously reported that the dietary flavonoids, luteolin and quercetin, might inhibit the invasiveness of cervical cancer by reversing…”
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A Novel Cyclic AMP/Epac1/CaMKI Signaling Cascade Promotes GCM1 Desumoylation and Placental Cell Fusion by Chang, Ching-Wen, Chang, Geen-Dong, Chen, Hungwen

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Endocytic pathway is required for Drosophila Toll innate immune signaling by Huang, Hon-Ren, Chen, Zhijian J, Kunes, Sam, Chang, Geen-Dong, Maniatis, Tom

“…The Toll signaling pathway is required for the innate immune response against fungi and Gram-positive bacteria in DROSOPHILA: Here we show that the endosomal…”
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Biochemical Regulation of the Glyoxalase System in Response to Insulin Signaling by Lee, Der-Yen, Lin, Yu-Chin, Chang, Geen-Dong

“…Methylglyoxal (MG) is a reactive glycation metabolite and potentially induces dicarbonyl stress. The production of MG in cells is increased along with an…”
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Activation of Akt by advanced glycation end products (AGEs): involvement of IGF-1 receptor and caveolin-1 by Yang, Su-Jung, Chen, Chen-Yu, Chang, Geen-Dong, Wen, Hui-Chin, Chen, Ching-Yu, Chang, Shi-Chuan, Liao, Jyh-Fei, Chang, Chung-Ho

“…Diabetes is characterized by chronic hyperglycemia, which in turn facilitates the formation of advanced glycation end products (AGEs). AGEs activate signaling…”
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A multi-omic analysis reveals the role of fumarate in regulating the virulence of enterohemorrhagic Escherichia coli by Kuo, Cheng-Ju, Wang, Sin-Tian, Lin, Chia-Mei, Chiu, Hao-Chieh, Huang, Cheng-Rung, Lee, Der-Yen, Chang, Geen-Dong, Chou, Ting-Chen, Chen, Jenn-Wei, Chen, Chang-Shi

“…The enteric pathogen enterohemorrhagic Escherichia coli (EHEC) is responsible for outbreaks of bloody diarrhea and hemolytic uremic syndrome (HUS) worldwide…”
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Functional Characterization of the Human Placental Fusogenic Membrane Protein Syncytin 2 by Chen, Chie-Pein, Chen, Liang-Fu, Yang, Su-Ray, Chen, Chia-Yu, Ko, Chun-Chuan, Chang, Geen-Dong, Chen, Hungwen

“…Fusion of cytotrophoblasts into the multinucleated syncytiotrophoblast layer is essential for the development of a functional placenta. The envelope protein of…”
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Hyperglycemia and advanced glycation end products (AGEs) suppress the differentiation of 3T3-L1 preadipocytes by Chang, Chia-Chu, Chen, Chen-Yu, Chang, Geen-Dong, Chen, Ting-Huan, Chen, Woan-Ling, Wen, Hui-Chin, Huang, Chih-Yang, Chang, Chung-Ho

“…Aging is characterized by mild hyperglycemia and accumulation of advanced glycation end products (AGEs). Effects of chronic exposure to hyperglycemia or AGEs…”
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Methylglyoxal in cells elicits a negative feedback loop entailing transglutaminase 2 and glyoxalase 1 by Lee, Der-Yen, Chang, Geen-Dong

“…Glyoxalase 1 (GlxI) is the key enzyme that converts the highly reactive α-oxo-aldehydes into the corresponding α-hydroxy acids using l-glutathione as a…”
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Tristetraprolin inhibits poly(A)-tail synthesis in nuclear mRNA that contains AU-rich elements by interacting with poly(A)-binding protein nuclear 1 by Su, Yu-Lun, Wang, Shun-Chang, Chiang, Pei-Yu, Lin, Nien-Yi, Shen, Yu-Fang, Chang, Geen-Dong, Chang, Ching-Jin

“…Tristetraprolin binds mRNA AU-rich elements and thereby facilitates the destabilization of mature mRNA in the cytosol. To understand how tristetraprolin…”
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GCMa Regulates the Syncytin-mediated Trophoblastic Fusion by Yu, Chenchou, Shen, Kuofeng, Lin, Meiyao, Chen, Porchun, Lin, Chenchen, Chang, Geen-Dong, Chen, Hungwen

“…The human placental trophoblast cell can be classified as either a cytotrophoblast or a syncytiotrophoblast. Cytotrophoblasts can function as stem cells for…”
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