Search Results - "Chang, Eugene B."

Inflammatory Bowel Diseases (IBD) and the Microbiome—Searching the Crime Scene for Clues by Lee, Mirae, Chang, Eugene B.

“…Inflammatory bowel diseases (IBD) develop via convergence of environmental, microbial, immunological, and genetic factors. Alterations in the gut microbiota…”
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Regional Diversity of the Gastrointestinal Microbiome by Martinez-Guryn, Kristina, Leone, Vanessa, Chang, Eugene B.

“…The role of gut microbes in health and disease has often been surmised from stool, which is easily sampled and rich in microbial diversity, density, and…”
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Intersection of the Gut Microbiome and Circadian Rhythms in Metabolism by Frazier, Katya, Chang, Eugene B.

“…The gut microbiome and circadian rhythms (CRs) both exhibit unique influence on mammalian hosts and have been implicated in the context of many diseases,…”
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The Human Microbiome and Obesity: Moving beyond Associations by Maruvada, Padma, Leone, Vanessa, Kaplan, Lee M., Chang, Eugene B.

“…Mounting evidence indicates that the gut microbiome responds to diet, antibiotics, and other external stimuli with speed and high precision and in ways that…”
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Gut microbiota as a transducer of dietary cues to regulate host circadian rhythms and metabolism by Choi, Hyoann, Rao, Mrinalini C., Chang, Eugene B.

“…Certain members of the gut microbiota exhibit diurnal variations in relative abundance and function to serve as non-canonical drivers of host circadian rhythms…”
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The microbial basis of inflammatory bowel diseases by Dalal, Sushila R, Chang, Eugene B

“…Inflammatory bowel diseases (IBD) are chronic, progressive diseases characterized by aberrant immune responses to environmental and gut microbial triggers in…”
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Intratumoral accumulation of gut microbiota facilitates CD47-based immunotherapy via STING signaling by Shi, Yaoyao, Zheng, Wenxin, Yang, Kaiting, Harris, Katharine G, Ni, Kaiyuan, Xue, Lai, Lin, Wenbin, Chang, Eugene B, Weichselbaum, Ralph R, Fu, Yang-Xin

“…Most studies focus on how intestinal microbiota influence cancer immunotherapy through activating gut immunity. However, immunotherapies related to innate…”
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Diet, gut microbes, and the pathogenesis of inflammatory bowel diseases by Dolan, Kyle T., Chang, Eugene B.

“…The rising incidence of inflammatory bowel diseases in recent decades has notably paralleled changing lifestyle habits in Western nations, which are now making…”
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Microbial metabolites in health and disease: Navigating the unknown in search of function by Martinez, Kristina B., Leone, Vanessa, Chang, Eugene B.

“…The gut microbiota has been implicated in the development of a number of chronic gastrointestinal and systemic diseases. These include inflammatory bowel…”
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Interactions between Diet, Bile Acid Metabolism, Gut Microbiota, and Inflammatory Bowel Diseases by Devkota, Suzanne, Chang, Eugene B

“…The composite human gut microbiomes of Western populations have changed over the past century, brought on by new environmental triggers that often have a…”
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Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10−/− mice by Devkota, Suzanne, Wang, Yunwei, Musch, Mark W., Leone, Vanessa, Fehlner-Peach, Hannah, Nadimpalli, Anuradha, Antonopoulos, Dionysios A., Jabri, Bana, Chang, Eugene B.

“…Consumption of a diet high in milk-derived fat is shown to increase the abundance of sulphite-reducing bacteria by altering bile composition, leading to…”
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The intestinal microbiota in the pathogenesis of inflammatory bowel diseases: new insights into complex disease by Harris, Katharine G, Chang, Eugene B

“…Inflammatory bowel diseases (IBD) are a group of chronic diseases of increasing worldwide prevalence characterized by gastrointestinal (GI) inflammation…”
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Small Intestine Microbiota Regulate Host Digestive and Absorptive Adaptive Responses to Dietary Lipids by Martinez-Guryn, Kristina, Hubert, Nathaniel, Frazier, Katya, Urlass, Saskia, Musch, Mark W., Ojeda, Patricia, Pierre, Joseph F., Miyoshi, Jun, Sontag, Timothy J., Cham, Candace M., Reardon, Catherine A., Leone, Vanessa, Chang, Eugene B.

“…The gut microbiota play important roles in lipid metabolism and absorption. However, the contribution of the small bowel microbiota of mammals to these…”
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Exercise prevents weight gain and alters the gut microbiota in a mouse model of high fat diet-induced obesity by Evans, Christian C, LePard, Kathy J, Kwak, Jeff W, Stancukas, Mary C, Laskowski, Samantha, Dougherty, Joseph, Moulton, Laura, Glawe, Adam, Wang, Yunwei, Leone, Vanessa, Antonopoulos, Dionysios A, Smith, Dan, Chang, Eugene B, Ciancio, Mae J

“…Diet-induced obesity (DIO) is a significant health concern which has been linked to structural and functional changes in the gut microbiota. Exercise (Ex) is…”
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Effects of Diurnal Variation of Gut Microbes and High-Fat Feeding on Host Circadian Clock Function and Metabolism by Leone, Vanessa, Gibbons, Sean M., Martinez, Kristina, Hutchison, Alan L., Huang, Edmond Y., Cham, Candace M., Pierre, Joseph F., Heneghan, Aaron F., Nadimpalli, Anuradha, Hubert, Nathaniel, Zale, Elizabeth, Wang, Yunwei, Huang, Yong, Theriault, Betty, Dinner, Aaron R., Musch, Mark W., Kudsk, Kenneth A., Prendergast, Brian J., Gilbert, Jack A., Chang, Eugene B.

“…Circadian clocks and metabolism are inextricably intertwined, where central and hepatic circadian clocks coordinate metabolic events in response to light-dark…”
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Diet, microbes, and host genetics: the perfect storm in inflammatory bowel diseases by Leone, Vanessa, Chang, Eugene B., Devkota, Suzanne

“…The incidence of inflammatory bowel diseases (IBD), as well as other inflammatory conditions, has dramatically increased over the past half century. While many…”
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Intestinal epithelial vitamin D receptor deletion leads to defective autophagy in colitis by Wu, Shaoping, Zhang, Yong-Guo, Lu, Rong, Xia, Yinglin, Zhou, David, Petrof, Elaine O, Claud, Erika C, Chen, Di, Chang, Eugene B, Carmeliet, Geert, Sun, Jun

“…Vitamin D and the vitamin D receptor (VDR) appear to be important immunological regulators of inflammatory bowel diseases (IBD). Defective autophagy has also…”
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Chronic Sleep Disruption Alters Gut Microbiota, Induces Systemic and Adipose Tissue Inflammation and Insulin Resistance in Mice by Poroyko, Valeriy A., Carreras, Alba, Khalyfa, Abdelnaby, Khalyfa, Ahamed A., Leone, Vanessa, Peris, Eduard, Almendros, Isaac, Gileles-Hillel, Alex, Qiao, Zhuanhong, Hubert, Nathaniel, Farré, Ramon, Chang, Eugene B., Gozal, David

“…Chronic sleep fragmentation (SF) commonly occurs in human populations, and although it does not involve circadian shifts or sleep deprivation, it markedly…”
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Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer’s disease by Minter, Myles R., Zhang, Can, Leone, Vanessa, Ringus, Daina L., Zhang, Xiaoqiong, Oyler-Castrillo, Paul, Musch, Mark W., Liao, Fan, Ward, Joseph F., Holtzman, David M., Chang, Eugene B., Tanzi, Rudolph E., Sisodia, Sangram S.

“…Severe amyloidosis and plaque-localized neuro-inflammation are key pathological features of Alzheimer’s disease (AD). In addition to astrocyte and microglial…”
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Commensal bacteria protect against food allergen sensitization by Stefka, Andrew T., Feehley, Taylor, Tripathi, Prabhanshu, Qiu, Ju, McCoy, Kathy, Mazmanian, Sarkis K., Tjota, Melissa Y., Seo, Goo-Young, Cao, Severine, Theriault, Betty R., Antonopoulos, Dionysios A., Zhou, Liang, Chang, Eugene B., Fu, Yang-Xin, Nagler, Cathryn R.

“…Significance The prevalence of food allergy is rising at an alarming rate; the US Centers for Disease Control and Prevention documented an 18% increase among…”
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