Search Results - "Chang, Edward F."

Towards Large-Scale, Human-Based, Mesoscopic Neurotechnologies by Chang, Edward F.

“…Direct human brain recordings have transformed the scope of neuroscience in the past decade. Progress has relied upon currently available neurophysiological…”
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Speech synthesis from neural decoding of spoken sentences by Anumanchipalli, Gopala K., Chartier, Josh, Chang, Edward F.

“…Technology that translates neural activity into speech would be transformative for people who are unable to communicate as a result of neurological…”
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Selective cortical representation of attended speaker in multi-talker speech perception by Mesgarani, Nima, Chang, Edward F.

“…The neural correlates of how attended speech is internally represented are described, shedding light on the ‘cocktail party problem’. Heard instinct The…”
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The Encoding of Speech Sounds in the Superior Temporal Gyrus by Yi, Han Gyol, Leonard, Matthew K., Chang, Edward F.

“…The human superior temporal gyrus (STG) is critical for extracting meaningful linguistic features from speech input. Local neural populations are tuned to…”
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Phonetic Feature Encoding in Human Superior Temporal Gyrus by Mesgarani, Nima, Cheung, Connie, Johnson, Keith, Chang, Edward F.

“…During speech perception, linguistic elements such as consonants and vowels are extracted from a complex acoustic speech signal. The superior temporal gyrus…”
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Functional organization of human sensorimotor cortex for speech articulation by Bouchard, Kristofer E., Mesgarani, Nima, Johnson, Keith, Chang, Edward F.

“…Speaking is one of the most complex actions that we perform, but nearly all of us learn to do it effortlessly. Production of fluent speech requires the…”
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Contemporary model of language organization: an overview for neurosurgeons by Chang, Edward F, Raygor, Kunal P, Berger, Mitchel S

“…Classic models of language organization posited that separate motor and sensory language foci existed in the inferior frontal gyrus (Broca's area) and superior…”
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A Spatial Map of Onset and Sustained Responses to Speech in the Human Superior Temporal Gyrus by Hamilton, Liberty S., Edwards, Erik, Chang, Edward F.

“…To derive meaning from speech, we must extract multiple dimensions of concurrent information from incoming speech signals. That is, equally important to…”
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Real-time decoding of question-and-answer speech dialogue using human cortical activity by Moses, David A., Leonard, Matthew K., Makin, Joseph G., Chang, Edward F.

“…Natural communication often occurs in dialogue, differentially engaging auditory and sensorimotor brain regions during listening and speaking. However,…”
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Multi-day rhythms modulate seizure risk in epilepsy by Baud, Maxime O., Kleen, Jonathan K., Mirro, Emily A., Andrechak, Jason C., King-Stephens, David, Chang, Edward F., Rao, Vikram R.

“…Epilepsy is defined by the seemingly random occurrence of spontaneous seizures. The ability to anticipate seizures would enable preventative treatment…”
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The Control of Vocal Pitch in Human Laryngeal Motor Cortex by Dichter, Benjamin K., Breshears, Jonathan D., Leonard, Matthew K., Chang, Edward F.

“…In speech, the highly flexible modulation of vocal pitch creates intonation patterns that speakers use to convey linguistic meaning. This human ability is…”
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Human cortical encoding of pitch in tonal and non-tonal languages by Li, Yuanning, Tang, Claire, Lu, Junfeng, Wu, Jinsong, Chang, Edward F.

“…Languages can use a common repertoire of vocal sounds to signify distinct meanings. In tonal languages, such as Mandarin Chinese, pitch contours of syllables…”
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Mood variations decoded from multi-site intracranial human brain activity by Sani, Omid G, Yang, Yuxiao, Lee, Morgan B, Dawes, Heather E, Chang, Edward F, Shanechi, Maryam M

“…Mood state changes are decoded using human neural activity data from electrodes implanted in seven epilepsy patients. The ability to decode mood state over…”
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New tools for studying microglia in the mouse and human CNS by Bennett, Mariko L., Bennett, F. Chris, Liddelow, Shane A., Ajami, Bahareh, Zamanian, Jennifer L., Fernhoff, Nathaniel B., Mulinyawe, Sara B., Bohlen, Christopher J., Adil, Aykezar, Tucker, Andrew, Weissman, Irving L., Chang, Edward F., Li, Gordon, Grant, Gerald A., Gephart, Melanie G. Hayden, Barres, Ben A.

“…The specific function of microglia, the tissue resident macrophages of the brain and spinal cord, has been difficult to ascertain because of a lack of tools to…”
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Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse by Zhang, Ye, Sloan, Steven A., Clarke, Laura E., Caneda, Christine, Plaza, Colton A., Blumenthal, Paul D., Vogel, Hannes, Steinberg, Gary K., Edwards, Michael S.B., Li, Gordon, Duncan, John A., Cheshier, Samuel H., Shuer, Lawrence M., Chang, Edward F., Grant, Gerald A., Gephart, Melanie G. Hayden, Barres, Ben A.

“…The functional and molecular similarities and distinctions between human and murine astrocytes are poorly understood. Here, we report the development of an…”
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Reconstructing speech from human auditory cortex by Pasley, Brian N, David, Stephen V, Mesgarani, Nima, Flinker, Adeen, Shamma, Shihab A, Crone, Nathan E, Knight, Robert T, Chang, Edward F

“…How the human auditory system extracts perceptually relevant acoustic features of speech is unknown. To address this question, we used intracranial recordings…”
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Brain2Char: a deep architecture for decoding text from brain recordings by Sun, Pengfei, Anumanchipalli, Gopala K, Chang, Edward F

“…Decoding language representations directly from the brain can enable new brain-computer interfaces (BCIs) for high bandwidth human-human and human-machine…”
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A single-cell atlas of the normal and malformed human brain vasculature by Winkler, Ethan A, Kim, Chang N, Ross, Jayden M, Garcia, Joseph H, Gil, Eugene, Oh, Irene, Chen, Lindsay Q, Wu, David, Catapano, Joshua S, Raygor, Kunal, Narsinh, Kazim, Kim, Helen, Weinsheimer, Shantel, Cooke, Daniel L, Walcott, Brian P, Lawton, Michael T, Gupta, Nalin, Zlokovic, Berislav V, Chang, Edward F, Abla, Adib A, Lim, Daniel A, Nowakowski, Tomasz J

“…Cerebrovascular diseases are a leading cause of death and neurologic disability. Further understanding of disease mechanisms and therapeutic strategies…”
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Perceptual restoration of masked speech in human cortex by Leonard, Matthew K., Baud, Maxime O., Sjerps, Matthias J., Chang, Edward F.

“…Humans are adept at understanding speech despite the fact that our natural listening environment is often filled with interference. An example of this capacity…”
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Glioblastoma remodelling of human neural circuits decreases survival by Krishna, Saritha, Choudhury, Abrar, Keough, Michael B., Seo, Kyounghee, Ni, Lijun, Kakaizada, Sofia, Lee, Anthony, Aabedi, Alexander, Popova, Galina, Lipkin, Benjamin, Cao, Caroline, Nava Gonzales, Cesar, Sudharshan, Rasika, Egladyous, Andrew, Almeida, Nyle, Zhang, Yalan, Molinaro, Annette M., Venkatesh, Humsa S., Daniel, Andy G. S., Shamardani, Kiarash, Hyer, Jeanette, Chang, Edward F., Findlay, Anne, Phillips, Joanna J., Nagarajan, Srikantan, Raleigh, David R., Brang, David, Monje, Michelle, Hervey-Jumper, Shawn L.

“…Gliomas synaptically integrate into neural circuits 1 , 2 . Previous research has demonstrated bidirectional interactions between neurons and glioma cells,…”
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