Search Results - "Chang, Dalu"
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1
Critical Analysis of Rate Constants and Turnover Frequency in Nucleic Acid-Templated Reactions: Reaching Terminal Velocity
Published in Journal of the American Chemical Society (01-02-2017)“…Nucleic acid-templated reactions have attracted significant attention for nucleic acid sensing and imaging. The level of signal amplification obtained from…”
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2
Pd-Catalyzed Difluoromethylation of Vinyl Bromides, Triflates, Tosylates, and Nonaflates
Published in Chemistry : a European journal (13-04-2015)“…Pd‐catalyzed difluoromethylation of di‐, tri‐ or tetra‐substituted vinyl bromides, triflates, tosylates and nonaflates under mild conditions is described. The…”
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3
Coupling of DNA Circuit and Templated Reactions for Quadratic Amplification and Release of Functional Molecules
Published in Journal of the American Chemical Society (16-10-2019)“…DNA-based circuitry empowers logic gated operations and amplifications but is restricted to nucleic acid output. Templated reactions enable the translation of…”
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4
Accelerating Turnover Frequency in Nucleic Acid Templated Reactions
Published in Bioconjugate chemistry (17-01-2018)“…Nucleic acid templated reactions have attracted attention as an important technology to sense oligonucleotides and to translate nucleic acid-based instructions…”
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5
Lysosome-targeted photoactivation reveals local sphingosine metabolism signatures
Published in Chemical science (Cambridge) (28-02-2019)“…Lipids are essential components of eukaryotic cell membranes and play crucial roles in cellular signaling and metabolism. While increasing evidence shows that…”
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6
Double‐Stranded RNA‐Specific Templated Reaction with Triplex Forming PNA
Published in Helvetica chimica acta (01-03-2018)“…RNA, originally perceived as a simple information transfer biopolymer, is emerging as an important regulator in cellular processes. A number of non‐coding RNAs…”
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7
Well-Defined, Shelf-Stable (NHC)Ag(CF2H) Complexes for Difluoromethylation
Published in Organometallics (22-06-2015)“…The preparation of the thermally stable, well-defined NHC-ligated difluoromethylated silver complexes 1a,b is described. The complexes were fully…”
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8
Luciferase‐Induced Photouncaging: Bioluminolysis
Published in Angewandte Chemie International Edition (04-11-2019)“…Bioluminescence resonance energy transfer (BRET) has been widely used for studying dynamic processes in biological systems such as protein–protein interactions…”
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9
Luciferase Controlled Protein Interactions
Published in Journal of the American Chemical Society (17-03-2021)“…Protein trafficking and protein–protein interactions (PPIs) are central to regulatory processes in cells. Induced dimerization systems have been developed to…”
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10
Function-guided proximity mapping unveils electrophilic-metabolite sensing by proteins not present in their canonical locales
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-2022)“…Enzyme-assisted posttranslational modifications (PTMs) constitute a major means of signaling across different cellular compartments. However, how nonenzymatic…”
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11
Enantioselective and Regioselective Friedel-Crafts Alkylation of Pyrroles with Nitroalkenes Catalyzed by a Tridentate Schiff Base-Copper Complex
Published in Chemistry : a European journal (26-09-2011)“…On a (pyr)role: A mild and highly efficient catalytic system has been developed for the asymmetric Friedel–Crafts alkylation of pyrroles with nitroalkenes (see…”
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12
Lysosome-targeted photoactivation reveals local sphingosine metabolism signaturesElectronic supplementary information (ESI) available. See DOI: 10.1039/c8sc03614d
Published 20-02-2019“…Lipids are essential components of eukaryotic cell membranes and play crucial roles in cellular signaling and metabolism. While increasing evidence shows that…”
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13
Lysosome-targeted photoactivation reveals local sphingosine metabolism signatures† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc03614d
Published in Chemical science (Cambridge) (26-12-2018)“…Novel photocaged lipids have been developed to release sphingosine at specific locations revealing a metabolic bias in ceramide synthesis based on subcellular…”
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14
Smartphone DNA or RNA Sensing Using Semisynthetic Luciferase-Based Logic Device
Published in ACS sensors (27-03-2020)“…Detection of specific oligonucleotide sequences is central to numerous applications, and technologies amenable to point-of-care diagnostics or end users are…”
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15
Luciferase‐Induced Photouncaging: Bioluminolysis
Published in Angewandte Chemie (04-11-2019)“…Bioluminescence resonance energy transfer (BRET) has been widely used for studying dynamic processes in biological systems such as protein–protein interactions…”
Get full text
Journal Article