Search Results - "Chang, Cheryl H."

A critical role for the mTORC2 pathway in lung fibrosis by Chang, Wenteh, Wei, Ke, Ho, Lawrence, Berry, Gerald J, Jacobs, Susan S, Chang, Cheryl H, Rosen, Glenn D

“…A characteristic of dysregulated wound healing in IPF is fibroblastic-mediated damage to lung epithelial cells within fibroblastic foci. In these foci, TGF-β…”
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Engineering a natural ligand-based CAR: directed evolution of the stress-receptor NKp30 by Butler, Savannah E., Brog, Rachel A., Chang, Cheryl H., Sentman, Charles L., Huang, Yina H., Ackerman, Margaret E.

“…B7H6, a stress-induced ligand which binds to the NK cell receptor NKp30, has recently emerged as a promising candidate for immunotherapy due to its…”
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Engineering a potent inhibitor of matriptase from the natural hepatocyte growth factor activator inhibitor type-1 (HAI-1) protein by Mitchell, Aaron C., Kannan, Deepti, Hunter, Sean A., Parra Sperberg, R. Andres, Chang, Cheryl H., Cochran, Jennifer R.

“…Dysregulated matriptase activity has been established as a key contributor to cancer progression through its activation of growth factors, including the…”
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Development of a Protease Biosensor Based on a Dimerization-Dependent Red Fluorescent Protein by Mitchell, Aaron C, Alford, Spencer C, Hunter, Sean A, Kannan, Deepti, Parra Sperberg, R. Andres, Chang, Cheryl H, Cochran, Jennifer R

“…Dysregulated activity of the protease matriptase is a key contributor to aggressive tumor growth, cancer metastasis, and osteoarthritis. Methods for the…”
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