Search Results - "Chandrasekaran, Finola Priyadharshini"

Molecular dynamics simulations involving different β-propeller mutations reported in Swiss and French patients correlate with their disease phenotypes by Chandrasekaran, Finola Priyadharshini, Nelson, Everette Jacob Remington

“…Integrin αIIbβ3 is the predominant receptor for fibrinogen which mediates platelet aggregation, an important step in hemostasis and thrombosis. Several…”
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Molecular dynamics simulations corroborate recombinant expression studies carried out on three αIIb β‐propeller mutations reported in Indian Glanzmann thrombasthenia patients by Chandrasekaran, Finola Priyadharshini, Vishal, Adarsh, Arora, Udita, Kumar S., Udhaya, George C., Priya Doss, Nelson, Everette Jacob Remington

“…Mutations in the αIIb β‐propeller domain have long been known to disrupt heterodimerization and intracellular trafficking of αIIbβ3 complexes leading to…”
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