Search Results - "Chandrasekar, Moola Joghee Nanjan"
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Virtual high throughput screening: Potential inhibitors for SARS-CoV-2 PLPRO and 3CLPRO proteases
Published in European journal of pharmacology (15-06-2021)“…The pandemic, COVID-19, has spread worldwide and affected millions of people. There is an urgent need, therefore, to find a proper treatment for the novel…”
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Positive allosteric activation of glial EAAT-2 transporter protein: A novel strategy for Alzheimer’s disease
Published in Medical hypotheses (01-09-2020)“…Excitatory amino acid transporter-2 (EAAT-2) protein localized in the membrane of glial cells are responsible for the clearance of glutamate in synapse and it…”
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Plant-based Natural Products for Wound Healing: A Critical Review
Published in Current drug research reviews (2022)“…Wound healing is an intricate process consisting of four overlapping phases, namely hemostasis, inflammation, proliferation, and remodelling. Effective…”
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4
Synthesis and Characterization of Dipeptide–Drug Conjugate: The Use of Linker Coupling Reaction
Published in International journal of peptide research and therapeutics (01-03-2022)“…Most of the effective anticancer drugs available in the market suffer from adverse effects due to their lack of target specificity. Therefore, so many delivery…”
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Phyllanthus maderaspatensis, a dietary supplement for the amelioration of adriamycin-induced toxicity and oxidative stress in mice
Published in Journal of natural medicines (01-04-2008)“…The effect of ethanol extract of Phyllanthus maderaspatensis (PME), a popular south Indian dietary supplement, was studied for its chemoprotective property on…”
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Repurposing of FDA Approved Drugs and Neuropep peptides as Anticancer Agents Against ErbB1 and ErbB2
Published in Drug research (01-07-2023)“…ErbB1 and ErbB2 are the most important biological targets in cancer drug discovery and development of dual inhibitors for the cancer therapy. FDA approved…”
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Downregulation of NT5C3 gene expressions by elastin-like polypeptide gemcitabine conjugate for ovarian cancer therapy
Published in Journal of drug delivery science and technology (01-10-2022)“…Due to the undesirable side effects and lack of target specificity of existing anticancer drugs the newer drug delivery system with target specificity and…”
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1-Tetracosanol isolated from the leaves of Eupatorium glandulosum, accelerates wound healing by expressing inflammatory cytokines and matrix metalloproteinase
Published in Journal of ethnopharmacology (28-10-2023)“…The leave paste of the plant, Eupatorium glandulosum H. B & K, has been traditionally used to treat cuts and wounds by the tribal community of the Nilgiris…”
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Potential inhibitors for FKBP51: an in silico study using virtual screening, molecular docking and molecular dynamics simulation
Published in Journal of biomolecular structure & dynamics (01-01-2022)“…Over the years, FK506-binding proteins have been targeted for different pharmaceutical interests. The FK506-binding protein, encoded by the FKBP5 gene, is…”
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10
Virtual high throughput screening: Potential inhibitors for SARS-CoV-2 PL PRO and 3CL PRO proteases
Published in European journal of pharmacology (15-06-2021)“…The pandemic, COVID-19, has spread worldwide and affected millions of people. There is an urgent need, therefore, to find a proper treatment for the novel…”
Get full text
Journal Article