Search Results - "Chandrahas, Anita"
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Resilience to autosomal dominant Alzheimer’s disease in a Reelin-COLBOS heterozygous man
Published in Nature medicine (01-05-2023)“…We characterized the world’s second case with ascertained extreme resilience to autosomal dominant Alzheimer’s disease (ADAD). Side-by-side comparisons of this…”
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The yeast lipin orthologue Pah1p is important for biogenesis of lipid droplets
Published in The Journal of cell biology (21-03-2011)“…Lipins are phosphatidate phosphatases that generate diacylglycerol (DAG). In this study, we report that yeast lipin, Pah1p, controls the formation of cytosolic…”
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APOE Christchurch‐mimetic therapeutic antibody reduces APOE‐mediated toxicity and tau phosphorylation
Published in Alzheimer's & dementia (01-02-2024)“…INTRODUCTION We discovered that the APOE3 Christchurch (APOE3Ch) variant may provide resistance to Alzheimer's disease (AD). This resistance may be due to…”
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Transcription Activator-like Effectors: A Toolkit for Synthetic Biology
Published in ACS synthetic biology (17-10-2014)“…Transcription activator-like effectors (TALEs) are proteins secreted by Xanthomonas bacteria to aid the infection of plant species. TALEs assist infections by…”
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Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators
Published in The American journal of pathology (01-07-2021)“…Pulmonary fibrosis (PF) can arise from unknown causes, as in idiopathic PF, or as a consequence of infections, including severe acute respiratory syndrome…”
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