Search Results - "Chandra, Ashley N."
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Role of DNA-Dependent Protein Kinase in Mediating Cyst Growth in Autosomal Dominant Polycystic Kidney Disease
Published in International journal of molecular sciences (29-09-2021)“…DNA-dependent protein kinase (DNA-PK) is a serine/threonine protein involved in DNA damage response (DDR) signaling that may mediate kidney cyst growth in…”
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Long-term dietary nitrate supplementation does not reduce renal cyst growth in experimental autosomal dominant polycystic kidney disease
Published in PloS one (22-04-2021)“…Augmentation of endogenous nitric oxide (NO) synthesis, either by the classical L-arginine-NO synthase pathway, or the recently discovered entero-salivary…”
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Assessment of Dietary Sodium Intake Using the Scored Salt Questionnaire in Autosomal Dominant Polycystic Kidney Disease
Published in Nutrients (02-11-2020)“…The excess intake of dietary sodium is a key modifiable factor for reducing disease progression in autosomal dominant polycystic kidney disease (ADPKD). The…”
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Up-Regulation of DNA Damage Response Signaling in Autosomal Dominant Polycystic Kidney Disease
Published in The American journal of pathology (01-05-2021)“…DNA damage and alterations in DNA damage response (DDR) signaling could be one of the molecular mechanisms mediating focal kidney cyst formation in autosomal…”
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Clinical characteristics and outcomes of hyponatraemia associated with oral water intake in adults: a systematic review
Published in BMJ open (09-12-2021)“…IntroductionExcessive water intake is rarely associated with life-threatening hyponatraemia. The aim of this study was to determine the clinical…”
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