Search Results - "Chandra, Anchal"

The Palmitoylation Machinery Is a Spatially Organizing System for Peripheral Membrane Proteins by Rocks, Oliver, Gerauer, Marc, Vartak, Nachiket, Koch, Sebastian, Huang, Zhi-Ping, Pechlivanis, Markos, Kuhlmann, Jürgen, Brunsveld, Lucas, Chandra, Anchal, Ellinger, Bernhard, Waldmann, Herbert, Bastiaens, Philippe I.H.

“…Reversible S-palmitoylation of cysteine residues critically controls transient membrane tethering of peripheral membrane proteins. Little is known about how…”
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Strategies to target SARS-CoV-2 entry and infection using dual mechanisms of inhibition by acidification inhibitors by Prabhakara, Chaitra, Godbole, Rashmi, Sil, Parijat, Jahnavi, Sowmya, Gulzar, Shah-E-Jahan, van Zanten, Thomas S, Sheth, Dhruv, Subhash, Neeraja, Chandra, Anchal, Shivaraj, Akshatha, Panikulam, Patricia, U, Ibrahim, Nuthakki, Vijay Kumar, Puthiyapurayil, Theja Parassini, Ahmed, Riyaz, Najar, Ashaq Hussain, Lingamallu, Sai Manoz, Das, Snigdhadev, Mahajan, Bhagyashri, Vemula, Praveen, Bharate, Sandip B, Singh, Parvinder Pal, Vishwakarma, Ram, Guha, Arjun, Sundaramurthy, Varadharajan, Mayor, Satyajit

“…Many viruses utilize the host endo-lysosomal network for infection. Tracing the endocytic itinerary of SARS-CoV-2 can provide insights into viral trafficking…”
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Genetically encoded live-cell sensor for tyrosinated microtubules by Kesarwani, Shubham, Lama, Prakash, Chandra, Anchal, Reddy, P Purushotam, Jijumon, A S, Bodakuntla, Satish, Rao, Balaji M, Janke, Carsten, Das, Ranabir, Sirajuddin, Minhajuddin

“…Microtubule cytoskeleton exists in various biochemical forms in different cells due to tubulin posttranslational modifications (PTMs). Tubulin PTMs are known…”
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Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling by Zimmermann, Gunther, Papke, Björn, Ismail, Shehab, Vartak, Nachiket, Chandra, Anchal, Hoffmann, Maike, Hahn, Stephan A., Triola, Gemma, Wittinghofer, Alfred, Bastiaens, Philippe I. H., Waldmann, Herbert

“…KRAS is one of the most frequently mutated oncogenes and a major target in anticancer drug discovery, but small molecule modulators that work in the clinic…”
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Nanobody derived using a peptide epitope from the spike protein receptor-binding motif inhibits entry of SARS-CoV-2 variants by Mendon, Nivya, Ganie, Rayees A., Kesarwani, Shubham, Dileep, Drisya, Sasi, Sarika, Lama, Prakash, Chandra, Anchal, Sirajuddin, Minhajuddin

“…The emergence of new escape mutants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has escalated its penetration among the human…”
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Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo by Ismail, Shehab A, Chen, Yong-Xiang, Rusinova, Alexandra, Chandra, Anchal, Bierbaum, Martin, Gremer, Lothar, Triola, Gemma, Waldmann, Herbert, Bastiaens, Philippe I H, Wittinghofer, Alfred

“…Trafficking G proteins between membranes is essential for their signaling activity. Structural and biochemical studies on the farnesylated G protein Rheb and…”
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The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins by Chandra, Anchal, Grecco, Hernán E., Pisupati, Venkat, Perera, David, Cassidy, Liam, Skoulidis, Ferdinandos, Ismail, Shehab A., Hedberg, Christian, Hanzal-Bayer, Michael, Venkitaraman, Ashok R., Wittinghofer, Alfred, Bastiaens, Philippe I. H.

“…We identify a role for the GDI-like solubilizing factor (GSF) PDEδ in modulating signalling through Ras family G proteins by sustaining their dynamic…”
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Small molecule inhibition of the KRAS-PDE[delta] interaction impairs oncogenic KRAS signalling by Zimmermann, Gunther, Papke, Björn, Ismail, Shehab, Vartak, Nachiket, Chandra, Anchal, Hoffmann, Maike, Hahn, Stephan A, Triola, Gemma, Wittinghofer, Alfred, Bastiaens, Philippe I H, Waldmann, Herbert

“…The KRAS oncogene product is considered a major target in anticancer drug discovery. However, direct interference with KRAS signalling has not yet led to…”
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The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins

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The GDI-like solubilizing factor PDE[delta] sustains the spatial organization and signalling of Ras family proteins by Chandra, Anchal, Grecco, Hernán E, Pisupati, Venkat, Perera, David, Cassidy, Liam, Skoulidis, Ferdinandos, Ismail, Shehab A, Hedberg, Christian, Hanzal-bayer, Michael, Venkitaraman, Ashok R, Wittinghofer, Alfred, Bastiaens, Philippe I H

“…We identify a role for the GDI-like solubilizing factor (GSF) PDEδ in modulating signalling through Ras family G proteins by sustaining their dynamic…”
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Erratum: The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins by Chandra, Anchal, Grecco, Hernán E., Pisupati, Venkat, Perera, David, Cassidy, Liam, Skoulidis, Ferdinandos, Ismail, Shehab A., Hedberg, Christian, Hanzal-Bayer, Michael, Venkitaraman, Ashok R., Wittinghofer, Alfred, Bastiaens, Philippe I. H.

“…Nat. Cell Biol. 14, 148–158 (2012); published online 18 December 2011; corrected after print 25 January 2012 In the version of this article initially published…”
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The GDI-like solubilizing factor PDE[delta] sustains the spatial organization and signalling of Ras family proteins by Chandra, Anchal, Grecco, Hernán E, Pisupati, Venkat, Perera, David, Cassidy, Liam, Skoulidis, Ferdinandos, Ismail, Shehab A, Hedberg, Christian, Hanzal-bayer, Michael, Venkitaraman, Ashok R, Wittinghofer, Alfred, Bastiaens, Philippe I H

“…We identify a role for the GDI-like solubilizing factor (GSF) PDEδ in modulating signalling through Ras family G proteins by sustaining their dynamic…”
Get full text