Search Results - "Chando, T J"

Biotransformation of Irbesartan in Man by CHANDO, T. J, EVERETT, D. W, KAHLE, A. D, STARRETT, A. M, VACHHARAJANI, N, WEN CHYI SHYU, KRIPALANI, K. J, BARBHAIYA, R. H

“…The metabolism of irbesartan, a highly selective and potent nonpeptide angiotensin II receptor antagonist, has been investigated in humans. An aliquot of…”
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Biotransformation of pravastatin sodium in humans by Everett, D W, Chando, T J, Didonato, G C, Singhvi, S M, Pan, H Y, Weinstein, S H

“…Pravastatin sodium (PV) is a potent cholesterol-lowering agent that acts by inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Biotransformation…”
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Oral Bioavailability and Disposition Characteristics of Irbesartan, an Angiotensin Antagonist, in Healthy Volunteers by Vachharajani, Nimish N., Shyu, Wen Chyi, Chando, Theodore J., Everett, Donald W., Greene, Douglas S., Barbhaiya, Rashmi H.

“…Absolute oral bioavailability and disposition characteristics of irbesartan, an angiotensin II receptor antagonist, were investigated in 18 healthy young male…”
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Percutaneous absorption of [3H]tretinoin and systemic exposure to mequinol after dermal application of 2% mequinol/0.01% [3H]tretinoin (Solagé®) solution in healthy volunteers by Everett, Donald W., Franz, Thomas J., Chando, Theodore J., Gale, P. Jane, Lehman, Paul A., Schwarzel, Edmund H., Parab, Prakash V., D'Arienzo, Celia J., Kripalani, Kishin J.

“…Solagé® is a combination product composed of 2% mequinol (4‐hydroxyanisole) and 0.01% tretinoin (all‐trans‐retinoic acid) in an ethanolic solution, which is…”
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IN VITRO INHIBITION OF UDP GLUCURONOSYLTRANSFERASES BY ATAZANAVIR AND OTHER HIV PROTEASE INHIBITORS AND THE RELATIONSHIP OF THIS PROPERTY TO IN VIVO BILIRUBIN GLUCURONIDATION by DONGLU ZHANG, CHANDO, Theodore J, VERETT, Donald W, PATTEN, Christopher J, DEHAL, Shangara S, HUMPHREYS, W. Griffith

“…Several human immunodeficiency virus (HIV) protease inhibitors, including atazanavir, indinavir, lopinavir, nelfinavir, ritonavir, and saquinavir, were tested…”
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Metabolism of 4-(3-(dimethylamino)propyl)-3,4-dihydro-2-(1-hydroxyethyl)-3-phenyl-2H-1,4-benzothiazine (SQ 11,579) under in vitro and in vivo conditions by rats, dogs, and monkey by Lan, S J, Chando, T J, Cohen, A I, Weliky, I, Schreiber, E C

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Metabolism of niflumic acid-14C: absorption, excretion and biotransformation by human and dog by Lan, S J, Chando, T J, Weliky, I, Schreiber, E C

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Hydroxylation of 14-C-niflumic acid by phenobarbital-induced rat liver microsomes by Lan, S J, Chando, T J, Schreiber, E C

“…Hydroxylation of niflumic acid to 4'-hydroxyniflumic acid and 5-hydroxyniflumic acid by rat liver microsomes from untreated animals or phenobarbital-pretreated…”
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