Search Results - "Chandler, I"

Current accounts of antimicrobial resistance: stabilisation, individualisation and antibiotics as infrastructure by Chandler, Clare I R

“…Antimicrobial resistance (AMR) is one of the latest issues to galvanise political and financial investment as an emerging global health threat. This paper…”
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Vertical variation of mixing within porous sediment beds below turbulent flows by Chandler, I. D., Guymer, I., Pearson, J. M., van Egmond, R.

“…River ecosystems are influenced by contaminants in the water column, in the pore water and adsorbed to sediment particles. When exchange across the…”
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Antimicrobial resistance and COVID-19: Intersections and implications by Knight, Gwenan M, Glover, Rebecca E, McQuaid, C Finn, Olaru, Ioana D, Gallandat, Karin, Leclerc, Quentin J, Fuller, Naomi M, Willcocks, Sam J, Hasan, Rumina, van Kleef, Esther, Chandler, Clare Ir

“…Before the coronavirus 2019 (COVID-19) pandemic began, antimicrobial resistance (AMR) was among the top priorities for global public health. Already a complex…”
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The complexities of simple technologies: re-imagining the role of rapid diagnostic tests in malaria control efforts by Beisel, Uli, Umlauf, René, Hutchinson, Eleanor, Chandler, Clare I R

“…Malaria rapid diagnostic tests (RDTs) are assumed to be simple-to-use and mobile technologies that have the capacity to standardize parasitological diagnosis…”
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Antibiotics, rational drug use and the architecture of global health in Zimbabwe by Dixon, Justin, Manyau, Salome, Kandiye, Faith, Kranzer, Katharina, Chandler, Clare I.R.

“…Rising concerns around antimicrobial resistance (AMR) have led to a renewed push to rationalise antibiotic prescribing in low- and middle-income countries…”
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Intermittent preventive treatment of malaria delivered to primary schoolchildren provided effective individual protection in Jinja, Uganda: secondary outcomes of a cluster-randomized trial (START-IPT) by Rehman, Andrea M, Maiteki-Sebuguzi, Catherine, Gonahasa, Samuel, Okiring, Jaffer, Kigozi, Simon P, Chandler, Clare I R, Drakeley, Chris, Dorsey, Grant, Kamya, Moses R, Staedke, Sarah G

“…Intermittent preventive treatment (IPT) of malaria is recommended as policy for certain high-risk populations, but not currently for schoolchildren. A…”
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Interobserver agreement in grading of colorectal cancers-findings from a nationwide web-based survey of histopathologists by Chandler, I, Houlston, R S

“…Aims:  Tumour grade represents a gestalt of all molecular changes in malignancy, reflecting aggressiveness and has been shown to add prognostic information…”
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Patients with positive malaria tests not given artemisinin-based combination therapies: a research synthesis describing under-prescription of antimalarial medicines in Africa by O'Boyle, Shennae, Bruxvoort, Katia J, Ansah, Evelyn K, Burchett, Helen E D, Chandler, Clare I R, Clarke, Siân E, Goodman, Catherine, Mbacham, Wilfred, Mbonye, Anthony K, Onwujekwe, Obinna E, Staedke, Sarah G, Wiseman, Virginia L, Whitty, Christopher J M, Hopkins, Heidi

“…There has been a successful push towards parasitological diagnosis of malaria in Africa, mainly with rapid diagnostic tests (mRDTs), which has reduced…”
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Introducing malaria rapid diagnostic tests in private medicine retail outlets: A systematic literature review by Visser, Theodoor, Bruxvoort, Katia, Maloney, Kathleen, Leslie, Toby, Barat, Lawrence M, Allan, Richard, Ansah, Evelyn K, Anyanti, Jennifer, Boulton, Ian, Clarke, Siân E, Cohen, Jessica L, Cohen, Justin M, Cutherell, Andrea, Dolkart, Caitlin, Eves, Katie, Fink, Günther, Goodman, Catherine, Hutchinson, Eleanor, Lal, Sham, Mbonye, Anthony, Onwujekwe, Obinna, Petty, Nora, Pontarollo, Julie, Poyer, Stephen, Schellenberg, David, Streat, Elizabeth, Ward, Abigail, Wiseman, Virginia, Whitty, Christopher J M, Yeung, Shunmay, Cunningham, Jane, Chandler, Clare I R

“…Many patients with malaria-like symptoms seek treatment in private medicine retail outlets (PMR) that distribute malaria medicines but do not traditionally…”
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The impact of an intervention to introduce malaria rapid diagnostic tests on fever case management in a high transmission setting in Uganda: A mixed-methods cluster-randomized trial (PRIME) by Chandler, Clare I R, Webb, Emily L, Maiteki-Sebuguzi, Catherine, Nayiga, Susan, Nabirye, Christine, DiLiberto, Deborah D, Ssemmondo, Emmanuel, Dorsey, Grant, Kamya, Moses R, Staedke, Sarah G

“…Rapid diagnostic tests for malaria (mRDTs) have been scaled-up widely across Africa. The PRIME study evaluated an intervention aiming to improve fever case…”
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Motivation, money and respect: A mixed-method study of Tanzanian non-physician clinicians by Chandler, Clare I.R., Chonya, Semkini, Mtei, Frank, Reyburn, Hugh, Whitty, Christopher J.M.

“…Poor quality of care is a major concern in low-income countries, and is in part attributed to low motivation of healthcare workers. Non-physician clinicians…”
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Guidelines and mindlines: why do clinical staff over-diagnose malaria in Tanzania? A qualitative study by Chandler, Clare I R, Jones, Caroline, Boniface, Gloria, Juma, Kaseem, Reyburn, Hugh, Whitty, Christopher J M

“…Malaria over-diagnosis in Africa is widespread and costly both financially and in terms of morbidity and mortality from missed diagnoses. An understanding of…”
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Introducing malaria rapid diagnostic tests at registered drug shops in Uganda: Limitations of diagnostic testing in the reality of diagnosis by Chandler, Clare I.R., Hall-Clifford, Rachel, Asaph, Turinde, Pascal, Magnussen, Clarke, Siân, Mbonye, Anthony K.

“…In Uganda, around two thirds of medicines are procured from the private sector, mostly from drug shops. The introduction of malaria rapid diagnostic tests…”
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‘As a clinician, you are not managing lab results, you are managing the patient’: How the enactment of malaria at health facilities in Cameroon compares with new WHO guidelines for the use of malaria tests by Chandler, Clare I.R., Mangham, Lindsay, Njei, Abanda Ngu, Achonduh, Olivia, Mbacham, Wilfred F., Wiseman, Virginia

“…In response to widespread overuse of antimalarial drugs, the World Health Organisation changed guidelines in 2010 to restrict the use of antimalarials to…”
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Community case management of malaria: exploring support, capacity and motivation of community medicine distributors in Uganda by Banek, Kristin, Nankabirwa, Joaniter, Maiteki-Sebuguzi, Catherine, DiLiberto, Deborah, Taaka, Lilian, Chandler, Clare I R, Staedke, Sarah G

“…In Uganda, community services for febrile children are expanding from presumptive treatment of fever with anti-malarials through the home-based management of…”
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Setting the standard: multidisciplinary hallmarks for structural, equitable and tracked antibiotic policy by Kirchhelle, Claas, Atkinson, Paul, Broom, Alex, Chuengsatiansup, Komatra, Ferreira, Jorge Pinto, Fortané, Nicolas, Frost, Isabel, Gradmann, Christoph, Hinchliffe, Stephen, Hoffman, Steven J, Lezaun, Javier, Nayiga, Susan, Outterson, Kevin, Podolsky, Scott H, Raymond, Stephanie, Roberts, Adam P, Singer, Andrew C, So, Anthony D, Sringernyuang, Luechai, Tayler, Elizabeth, Rogers Van Katwyk, Susan, Chandler, Clare I R

“…There is increasing concern globally about the enormity of the threats posed by antimicrobial resistance (AMR) to human, animal, plant and environmental…”
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Understanding Antibiotic Use in Companion Animals: A Literature Review Identifying Avenues for Future Efforts by Tompson, Alice C., Mateus, Ana L. P., Brodbelt, Dave C., Chandler, Clare I. R.

“…Addressing antibiotic use is essential to tackle antimicrobial resistance, a major human and animal health challenge. This review seeks to inform stewardship…”
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Assessment of community-level effects of intermittent preventive treatment for malaria in schoolchildren in Jinja, Uganda (START-IPT trial): a cluster-randomised trial by Staedke, Sarah G, Maiteki-Sebuguzi, Catherine, Rehman, Andrea M, Kigozi, Simon P, Gonahasa, Samuel, Okiring, Jaffer, Lindsay, Steve W, Kamya, Moses R, Chandler, Clare I R, Dorsey, Grant, Drakeley, Chris

“…Intermittent preventive treatment (IPT) is a well established malaria control intervention. Evidence that delivering IPT to schoolchildren could provide…”
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Water, sanitation and hygiene (WASH): the evolution of a global health and development sector by de Wit, Sara, Luseka, Euphrasia, Bradley, David, Brown, Joe, Bhagwan, Jayant, Evans, Barbara, Freeman, Matthew C, Howard, Guy, Ray, Isha, Ross, Ian, Simiyu, Sheillah, Cumming, Oliver, Chandler, Clare I R

“…Despite some progress, universal access to safe water, sanitation and hygiene (WASH) by 2030—a remit of Sustainable Development Goal 6—remains a distant…”
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Understanding antimicrobial resistance through the lens of antibiotic vulnerabilities in primary health care in rural Malawi by MacPherson, Eleanor E., Reynolds, Joanna, Sanudi, Esnart, Nkaombe, Alexander, Phiri, Chimwemwe, Mankhomwa, John, Dixon, Justin, Chandler, Clare I.R.

“…The diminishing effectiveness of antimicrobials raises serious concerns for human health. While policy makers grapple to reduce the overuse of antimicrobial…”
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