Search Results - "Chandak, Giriraj Ratan"

Genetic mechanisms underlying the pathogenesis of tropical calcific pancreatitis by Mahurkar, Swapna, Reddy, D Nageshwar, Rao, G Venkat, Chandak, Giriraj Ratan

“…Chronic pancreatitis is known to be a heterogeneous disease with varied etiologies. Tropical calcific pancreatitis （TCP） is a severe form of chronic…”
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Genetic architecture of adiposity measures among Asians: Findings from GWAS by Agarwal, Tripti, Lyngdoh, Tanica, Khadgawat, Rajesh, Prabhakaran, Dorairaj, Chandak, Giriraj Ratan, Walia, Gagandeep Kaur

“…Abstract Adiposity has gradually become a global public threat over the years with drastic increase in the attributable deaths and disability adjusted life…”
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Towards a new developmental synthesis: adaptive developmental plasticity and human disease by Gluckman, Peter D, Prof, Hanson, Mark A, Prof, Bateson, Patrick, Prof, Beedle, Alan S, PhD, Law, Catherine M, MD, Bhutta, Zulfiqar A, Prof, Anokhin, Konstantin V, Prof, Bougnères, Pierre, Prof, Chandak, Giriraj Ratan, MD, Dasgupta, Partha, Prof, Smith, George Davey, Prof, Ellison, Peter T, Prof, Forrester, Terrence E, Prof, Gilbert, Scott F, Prof, Jablonka, Eva, PhD, Kaplan, Hillard, Prof, Prentice, Andrew M, Prof, Simpson, Stephen J, Prof, Uauy, Ricardo, Prof, West-Eberhard, Mary Jane, PhD

“…Consideration of the outcomes of developmental plasticity acting over the intermediate timescale is now important.20 Developmental plasticity evolved because…”
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Chronic maternal vitamin B12 restriction induced changes in body composition & glucose metabolism in the Wistar rat offspring are partly correctable by rehabilitation by Kumar, Kalle Anand, Lalitha, Anumula, Reddy, Umakar, Chandak, Giriraj Ratan, Sengupta, Shantanu, Raghunath, Manchala

“…Maternal under-nutrition increases the risk of developing metabolic diseases. We studied the effects of chronic maternal dietary vitamin B12 restriction on…”
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Comprehensive screening for reg1α gene rules out association with tropical calcific pancreatitis by Mahurkar, Swapna, Bhaskar, Seema, Reddy, D Nageshwar, Rao, G Venkat, Chandak, Giriraj Ratan

“…AIM： To investigate the allelic and haplotypic association of reg1α gene with tropical calcific pancreatitis （TCP）. Since TCP is known to have a variable…”
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Maternal vitamin B12 deficiency in rats alters DNA methylation in metabolically important genes in their offspring by Tanwar, Vinay Singh, Ghosh, Sourav, Sati, Satish, Ghose, Subhoshree, Kaur, Lovejeet, Kumar, Kalle Anand, Shamsudheen, K. V., Patowary, Ashok, Singh, Meghna, Jyothi, V., Kommineni, Pujitha, Sivasubbu, Sridhar, Scaria, Vinod, Raghunath, Manchala, Mishra, Rakesh, Chandak, Giriraj Ratan, Sengupta, Shantanu

“…Vitamin B 12 deficiency is a critical problem worldwide and peri-conceptional deficiency of this vitamin is associated with the risk of complex…”
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Maternal dietary folate and/or vitamin B₁₂ restrictions alter body composition (adiposity) and lipid metabolism in Wistar rat offspring by Kumar, Kalle Anand, Lalitha, Anumula, Pavithra, Dhandapani, Padmavathi, Inagadapa J.N, Ganeshan, Manisha, Rao, Kalashikam Rajender, Venu, Lagishetty, Balakrishna, Nagala, Shanker, Nemani Hari, Reddy, Singi Umakar, Chandak, Giriraj Ratan, Sengupta, Shantanu, Raghunath, Manchala

“…Maternal vitamin deficiencies are associated with low birth weight and increased perinatal morbidity and mortality. We hypothesize that maternal folate and/or…”
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Causal relationships between lipid and glycemic levels in an Indian population: A bidirectional Mendelian randomization approach by Agarwal, Tripti, Lyngdoh, Tanica, Dudbridge, Frank, Chandak, Giriraj Ratan, Kinra, Sanjay, Prabhakaran, Dorairaj, Reddy, K Srinath, Relton, Caroline L, Davey Smith, George, Ebrahim, Shah, Gupta, Vipin, Walia, Gagandeep Kaur

“…Dyslipidemia and abnormal glycemic traits are leading causes of morbidity and mortality. Although the association between the two traits is well established,…”
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High resolution methylome map of rat indicates role of intragenic DNA methylation in identification of coding region by Sati, Satish, Tanwar, Vinay Singh, Kumar, K Anand, Patowary, Ashok, Jain, Vaibhav, Ghosh, Sourav, Ahmad, Shadab, Singh, Meghna, Reddy, S Umakar, Chandak, Giriraj Ratan, Raghunath, Manchala, Sivasubbu, Sridhar, Chakraborty, Kausik, Scaria, Vinod, Sengupta, Shantanu

“…DNA methylation is crucial for gene regulation and maintenance of genomic stability. Rat has been a key model system in understanding mammalian systemic…”
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Comprehensive screening of chymotrypsin C (CTRC) gene in tropical calcific pancreatitis identifies novel variants by Paliwal, Sumit, Bhaskar, Seema, Mani, K Radha, Reddy, D Nageshwar, Rao, G Venkat, Singh, Shivaram Prasad, Thomas, Varghese, Chandak, Giriraj Ratan

“…In a previous study, the authors have shown that rather than variants in trypsinogen gene(s), mutations in pancreatic secretory trypsin inhibitor (encoded by…”
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Association of common genetic variants with lipid traits in the Indian population by Walia, Gagandeep Kaur, Gupta, Vipin, Aggarwal, Aastha, Asghar, Mohammad, Dudbridge, Frank, Timpson, Nicholas, Singh, Nongmaithem Suraj, Kumar, M Ravi, Kinra, Sanjay, Prabhakaran, Dorairaj, Reddy, K Srinath, Chandak, Giriraj Ratan, Smith, George Davey, Ebrahim, Shah

“…Genome-wide association studies (GWAS) have been instrumental in identifying novel genetic variants associated with altered plasma lipid levels. However, these…”
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Association Analysis of PRSS1-PRSS2 and CLDN2-MORC4 Variants in Nonalcoholic Chronic Pancreatitis Using Tropical Calcific Pancreatitis as Model by Paliwal, Sumit, Bhaskar, Seema, Nageshwar Reddy, D, Rao, G Venkat, Thomas, Varghese, Singh, Shivaram Prasad, Chandak, Giriraj Ratan

“…Association of PRSS1-PRSS2 (rs10273639) and CLDN2-MORC4 (rs12688220 and rs7057398) variants with alcohol-related chronic pancreatitis (CP) is established but…”
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PPAR signaling pathway is a key modulator of liver proteome in pups born to vitamin B12 deficient rats by Ahmad, Shadab, Kumar, K Anand, Basak, Trayambak, Bhardwaj, Gourav, Yadav, Dilip K., Lalitha, A., Chandak, Giriraj Ratan, Raghunath, Manchala, Sengupta, Shantanu

“…Maternal nutritional deficiency in-utero is known to predict risk of complex disorders like cardiovascular disease, diabetes and many neurological disorders in…”
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Association study of 25 type 2 diabetes related Loci with measures of obesity in Indian sib pairs by Gupta, Vipin, Vinay, Donipadi Guru, Sovio, Ulla, Rafiq, Sajjad, Kranthi Kumar, Madamchetty Venkata, Janipalli, Charles Spurgeon, Evans, David, Mani, Kulathu Radha, Sandeep, Madana Narasimha, Taylor, Amy, Kinra, Sanjay, Sullivan, Ruth, Bowen, Liza, Timpson, Nicholas, Smith, George Davey, Dudbridge, Frank, Prabhakaran, Dorairaj, Ben-Shlomo, Yoav, Reddy, Kolli Srinath, Ebrahim, Shah, Chandak, Giriraj Ratan

“…Obesity is an established risk factor for type 2 diabetes (T2D) and they are metabolically related through the mechanism of insulin resistance. In order to…”
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Assessing the pathological relevance of SPINK1 promoter variants by BOULLING, Arnaud, WITT, Heiko, RATAN CHANDAK, Giriraj, MASSON, Emmanuelle, PALIWAL, Sumit, BHASKAR, Seema, NAGESHWAR REDDY, D, COOPER, David N, CHEN, Jian-Min, FEREC, Claude

“…The SPINK1 gene, encoding the human pancreatic secretory trypsin inhibitor, is one of the major genes involved in predisposition to chronic pancreatitis (CP)…”
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Genetic analysis of the glycoprotein 2 gene in patients with chronic pancreatitis by Masson, Emmanuelle, Paliwal, Sumit, Bhaskar, Seema, Prakash, Soami, Scotet, Virginie, Reddy, D Nageshwar, Le Maréchal, Cédric, Ratan Chandak, Giriraj, Chen, Jian-Min, Férec, Claude

“…The aim of this study was to evaluate whether variations in the glycoprotein 2 gene (GP2) may potentially affect the risk of chronic pancreatitis. Six hundred…”
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High Prevalence of Infantile Encephalitic Beriberi with Overlapping Features of Leigh's Disease by Narasimha Rao, S., Mani, Shalini, Madap, Karuna, Kranthi Kumar, M. V., Singh, Lalji, Chandak, Giriraj Ratan

“…Infantile encephalitic beriberi (IEBB) is a rare form of thiamine deficiency and is poorly described. A proportion of Leigh's disease (LD) patients have…”
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Evaluation of genetic markers linked to hemophilia A locus: an Indian experience by Saha, Atreyee, Mukherjee, Saibal, Maulik, Mahua, Chandak, Giriraj Ratan, The Indian Genome Variation Consortium, Ray, Kunal

“…* Molecular & Human Genetics Division, Indian Institute of Chemical Biology, Kolkata, India; ° Genome Research Group, Centre for Cellular and Molecular…”
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Rapid and accurate nucleobase detection using FnCas9 and its application in COVID-19 diagnosis by Azhar, Mohd, Phutela, Rhythm, Kumar, Manoj, Ansari, Asgar Hussain, Rauthan, Riya, Gulati, Sneha, Sharma, Namrata, Sinha, Dipanjali, Sharma, Saumya, Singh, Sunaina, Acharya, Sundaram, Sarkar, Sajal, Paul, Deepanjan, Kathpalia, Poorti, Aich, Meghali, Sehgal, Paras, Ranjan, Gyan, Bhoyar, Rahul C., Singhal, Khushboo, Lad, Harsha, Patra, Pradeep Kumar, Makharia, Govind, Chandak, Giriraj Ratan, Pesala, Bala, Chakraborty, Debojyoti, Maiti, Souvik

“…Rapid detection of DNA/RNA pathogenic sequences or variants through point-of-care diagnostics is valuable for accelerated clinical prognosis, as witnessed…”
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Novel genomic variants related to visceral adiposity index (VAI) and body adiposity index (BAI) in Indian sib-pairs by Agarwal, Tripti, Lyngdoh, Tanica, Khadgawat, Rajesh, Dudbridge, Frank, Kinra, Sanjay, Relton, Caroline, Smith, George Davey, Ebrahim, Shah, Prabhakaran, Dorairaj, Chandak, Giriraj Ratan, Gupta, Vipin, Walia, Gagandeep Kaur

“…Background Obesity is among the leading public health threats globally. Over the last few years, visceral adiposity index (VAI), and body adiposity index…”
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