Search Results - "Chanda, Monica"

Metabolic engineering generates a transgene-free safety switch for cell therapy by Wiebking, Volker, Patterson, James O., Martin, Renata, Chanda, Monica K., Lee, Ciaran M., Srifa, Waracharee, Bao, Gang, Porteus, Matthew H.

“…Safeguard mechanisms can ameliorate the potential risks associated with cell therapies but currently rely on the introduction of transgenes. This limits their…”
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The Dynamic Relationship of Breast Cancer Cells and Fibroblasts in Fibronectin Accumulation at Primary and Metastatic Tumor Sites by Libring, Sarah, Shinde, Aparna, Chanda, Monica K, Nuru, Maryam, George, Heather, Saleh, Aya M, Abdullah, Ammara, Kinzer-Ursem, Tamara L, Calve, Sarah, Wendt, Michael K, Solorio, Luis

“…In breast cancer (BC), tissue stiffening via fibronectin (FN) and collagen accumulation is associated with advanced disease progression at both the primary…”
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Combined analysis of T cell activation and T cell-mediated cytotoxicity by imaging cytometry by Chanda, Monica K., Shudde, Claire E., Piper, Taylor L., Zheng, Yating, Courtney, Adam H.

“…Immunotherapies for the treatment of cancer have spurred the development of new drugs that seek to harness the ability of T cells to recognize and kill…”
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Fibronectin-Expressing Mesenchymal Tumor Cells Promote Breast Cancer Metastasis by Jun, Brian H., Guo, Tianqi, Libring, Sarah, Chanda, Monica K., Paez, Juan Sebastian, Shinde, Aparna, Wendt, Michael K., Vlachos, Pavlos P., Solorio, Luis

“…Tumor metastasis is connected to epithelial-mesenchymal heterogeneity (EMH) and the extracellular matrix (ECM) within the tumor microenvironment…”
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Advances in the discovery and development of melanoma drug therapies by Chanda, Monica, Cohen, Mark S

“…Therapeutic strategies for melanoma have evolved significantly over the last decade shifting from cytotoxic chemotherapies like dacarbazine to targeted…”
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Uncovering the role of STAT5 in CD8+ T cell fate by Chanda, Monica Kasturi, Gu, Zehui, Piper, Taylor L, Shudde, Claire E, Courtney, Adam H

“…Abstract Long-term protection against infection and disease requires long-lived memory CD8+ T cells. The development of these memory CD8+ T cells requires a…”
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Combined analysis of T cell activation and T cell-mediated cytotoxicity by imaging cytometry by Chanda, Monica Kasturi, Shudde, Claire E, Piper, Taylor L, Zheng, Yating, Courtney, Adam H

“…Abstract Immunotherapies have transformed the treatment of cancer through the development of drugs that allow T cells to recognize and kill malignant cells…”
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An engineered viral protein rewires signaling pathways to overcome T cell suppression by Zheng, Yating, Gu, Zehui, Shudde, Claire, Piper, Taylor, Wang, Xinyu, Aleck, Grace, Zhou, Jiajia, Chanda, Monica, Trinch, Lilliana, Zou, Weiping, Courtney, Adam

“…Abstract Cancer can evade destruction by depriving T cells of cytokines, such as IL-2, that cause JAK-STAT signaling required for T cell functionality. We…”
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A novel C-terminal Hsp90 inhibitor KU758 synergizes efficacy in combination with BRAF or MEK inhibitors and targets drug-resistant pathways in BRAF-mutant melanomas by Sanchez, Jackee N., Subramanian, Chitra, Chanda, Monica, Shanguan, Gary, Zhang, Nina, Wang, Ton, Timmermann, Barbara N., Blagg, Brian S.J., Cohen, Mark S.

“…Melanoma remains the most aggressive and fatal form of skin cancer, despite several FDA-approved targeted chemotherapies and immunotherapies for use in…”
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The Role Of CD90 in Breast Cancer Tumor Progression by Chanda, Monica Kasturi

“…Breast cancer is the most common cancer among women, with effective treatments if the disease stays local. However, if the tumor metastasizes, patient outcomes…”
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Correlation of Structural and Macroscopic Properties of Starches with Their Tabletability Using the SM(2) Approach by Dave, Vivek S, Chanda, Monica, Sayles, Matt, Popielarczyk, Michael, Boyce, Heather, Bompelliwar, Sai Krishna, Bates, Simon, Morris, Ken R, Haware, Rahul V

“…The effects of PURE-DENT® and SPRESS® starch properties on their compression behavior was characterized using "SM(2) " approach (structural properties,…”
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