Search Results - "Chanal, J L"

Effects of caffeine ingestion on performance and anaerobic metabolism during the Wingate Test by Collomp, K, Ahmaidi, S, Audran, M, Chanal, J L, Préfaut, C

“…In order to determine the effects of caffeine ingestion on performance and metabolic responses during supramaximal exercise, six healthy volunteers performed…”
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Pharmacokinetics and pharmacodynamics of recombinant human erythropoietin in athletes. Blood sampling and doping control by SOUILLARD, AGNES, AUDRAN, MICHEL, BRESSOLLE, FRANÇOISE, GAREAU, RAYNALD, DUVALLET, ALAIN, CHANAL, JEAN‐LOUIS

“…1The pharmacokinetics of recombinant human erythropoietin (rHuEpo) were initially determined in two healthy volunteers after a single subcutaneous dose (50 u…”
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Transferrin soluble receptor: a possible probe for detection of erythropoietin abuse by athletes by Gareau, R, Gagnon, M G, Thellend, C, Chénard, C, Audran, M, Chanal, J L, Ayotte, C, Brisson, G R

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Effects of moderate exercise on the pharmacokinetics of caffeine by COLLOMP, K, ANSELME, F, AUDRAN, M, GAY, J. P, CHANAL, J. L, PREFAUT, C

“…The effect of moderate exercise on the kinetics of caffeine in 12 healthy volunteers-6 heavy coffee drinkers (HD) and 6 light coffee drinkers (LD) has been…”
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Determination of urinary testosterone and epitestosterone during pubertal development: a cross-sectional study in 141 normal male subjects by Raynaud, E, Audran, M, Pagès, J C, Fédou, C, Brun, J F, Chanal, J L, Orsetti, A

“…Exogenous testosterone administration is classically detected by measuring the ratio of testosterone to epitestosterone in urine. Athletes are considered to be…”
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False-positive cases in detection of testosterone doping by Raynaud, E, Audran, M, Brun, J F, Fedou, C, Chanal, J L, Orsetti, A

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Mice's rectum radioprotection: comparative efficacy of a series of aminothiols and aminothiol precursors by Schumacher, C, Paul, K, Robbe, Y, Sicart, M T, Chanal, J L, Delard, R, Dubois, J B

“…In mice, in a test of rectal gamma irradiation, cysteamine and cysteine are poor radioprotectors relative to thiazolanes or WR 2721. Among the tested prodrugs,…”
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Mice's brain radioprotection: comparative efficacy of a series of aminothiols and aminothiol precursors by Schumacher, C, Paul, K, Robbe, Y, Sicart, M T, Subra, G, Chanal, J L, Delard, R, Dubois, J B

“…A serie of radioprotective aminothiols was checked upon irradiation of the mice's brain. Cysteamine protects efficiently the brain as soon as 15 minutes after…”
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The radioprotective power of 2-isopropyl 5-methyl 1,3-thiazolane by Schumacher, C P, Robbe, Y, Subra, G, Chanal, J L, Delard, R, Dubois, J B

“…The adequate conditions of radioprotective treatment with 2-isopropyl 5-methyl 1,3-thiazolane were established for mice. Protection is maximum with a unique…”
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Effects of benzodiazepine during a Wingate test: interaction with caffeine by Collomp, K R, Ahmaidi, S B, Caillaud, C F, Audran, M A, Chanal, J L, Préfaut, C G

“…To assess the effects of benzodiazepine alone and associated with caffeine on performance and substrate responses during supramaximal exercise, seven healthy…”
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Brain penetration of orally administered sodium pyroglutamate by Chanal, J L, Audran, M, Sicard, M T, Briley, M

“…The absorption and brain penetration of [3H]pyroglutamate was determined after oral administration to rats. Gas-liquid chromatography of the methylated…”
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Photopharmacology of the tranquilizer chlordiazepoxide in relation to its phototoxicity by Bakri, A, Beijersbergen van Henegouwen, G M, Chanal, J L

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Percutaneous absorption of 5-iodo-2' deoxycytidine in the hairless rat and in man by WEPIERRE, J, MARTY, J. P, CHANAL, J. L, SINCHOLLE, D

“…A study of percutaneous absorption of the anti-herpetic agent 5-iodo-2' deoxycytidine (IDC) was performed in vitro on the rat and on man and in vivo on the…”
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Relationship between metabolism and radioprotective activity of 2-phenylthiazolidine and its m-bromo derivative by Fernandez, J. P, Robbe, Y, Chapat, J. P, Chanal, J. L, Genin, M, Sentenac-Roumanou, H, Fatome, M

“…Molecular biotransformation of 2-phenylthiazolidine (1) and its m-bromo derivative (2) in the mouse is followed by autoradiographic studies and assessed by…”
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Pharmacokinetic and metabolic study of itanoxone in the crab Pachygrapsus marmoratus (Decapoda, Brachyura): comparative study with clofibric acid by Lautier, J, Chanal, J L, Delhon, A

“…The LD50 of itanoxone injected i.v. in the crab Pachygrapsus marmoratus is 144 mg/kg. Hypolipidemic drug distribution is distinct according to organ and sex…”
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Toxicokinetic and metabolic study of dimethylnitrosamine and diethylnitrosamine in crayfish Austropotamobius pallipes by Alibaud, R, Bontoux, J, Rambaud, A, Lautier, J, Chanal, J L

“…The acute toxicities of dimethylnitrosamine and diethylnitrosamine have been evaluated in adult male crayfish Austropotamobius pallipes; LD50 values are 2250…”
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Involvement of the N4-oxide group in the phototoxicity of chlordiazepoxide in the rat by Bakri, A, Beijersbergen van Henegouwen, G, Chanal, J L

“…To verify whether or not N4-oxide function is involved in the phototoxicity of chlordiazepoxide (CDZ, Librium), photopharmacology of reduced chlordiazepoxide…”
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Comparison of the metabolism and pharmacokinetics of metbufen and itanoxone and their analogues in rats by Chanal, J L, Audran, M, Bret, M C, Cousse, H, Fauran, F, Rieu, J P

“…Metbufen, II, itanoxone, I, and two other derivatives of gamma-aryl-gamma-keto-substituted butyric acids labelled with 14C in their carbonyl group were…”
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A pharmacokinetic study in rats of a new anorectic drug: the p-3-anisoyl-1,2,2-trimethyl-cyclopentane carboxylic acid by Chanal, J L, Chevallet, P, Sicart, M T, Orzalesi, H, Serrano, J J, Boucard, M

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Absorption and elimination of (14C) hesperidin methylchalcone in the rat by Chanal, J L, Cousse, H, Sicart, M T, Bonnaud, B, Marignan, R

“…Hesperidin methylchalcone resorption and excretion were studied in rats, using 14C-labelling. The level of radioactivity in the blood showed a peak 1-2 hours…”
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