Search Results - "Chan, Yau Sang"

Shiga toxins: from structure and mechanism to applications by Chan, Yau Sang, Ng, Tzi Bun

“…Shiga toxins are a group of type 2 ribosome-inactivating proteins (RIPs) produced in several types of bacteria. The toxins possess an AB 5 structure, which…”
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SCD1/FADS2 fatty acid desaturases equipoise lipid metabolic activity and redox-driven ferroptosis in ascites-derived ovarian cancer cells by Xuan, Yang, Wang, Huogang, Yung, Mingo Mh, Chen, Fushun, Chan, Wai-Sun, Chan, Yau-Sang, Tsui, Stephen Kw, Ngan, Hextan Ys, Chan, Karen Kl, Chan, David W

“…Malignant ascites in peritoneal metastases is a lipid-enriched microenvironment and is frequently involved in the poor prognosis of epithelial ovarian cancer…”
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Genome-wide DNA methylome analysis identifies methylation signatures associated with survival and drug resistance of ovarian cancers by Chan, David W, Lam, Wai-Yip, Chen, Fushun, Yung, Mingo M H, Chan, Yau-Sang, Chan, Wai-Sun, He, Fangfang, Liu, Stephanie S, Chan, Karen K L, Li, Benjamin, Ngan, Hextan Y S

“…In contrast to stable genetic events, epigenetic changes are highly plastic and play crucial roles in tumor evolution and development. Epithelial ovarian…”
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MAP30 protein from Momordica charantia is therapeutic and has synergic activity with cisplatin against ovarian cancer in vivo by altering metabolism and inducing ferroptosis by Chan, David W, Yung, Mingo MH, Chan, Yau-Sang, Xuan, Yang, Yang, Huijuan, Xu, Dakang, Zhan, Jin-Biao, Chan, Karen KL, Ng, Tzi-Bun, Ngan, Hextan YS

“…[Display omitted] Increasing evidence shows that Traditional Chinese Medicine (TCM) has an obvious appeal for cancer treatment, but there is still a lack of…”
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A glucuronic acid binding leguminous lectin with mitogenic activity toward mouse splenocytes by Chan, Yau Sang, Wong, Jack Ho, Ng, Tzi Bun

“…A dimeric 64-kDa lectin was purified from seeds of French bean (Phaseolus vulgaris) cultivar number 1. The purification protocol entailed Q-Sepharose, Affi-gel…”
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A cytokine-inducing hemagglutinin from small taros by Chan, Yau Sang, Wong, Jack Ho, Ng, Tzi Bun

“…A 22.4-kDa dimeric hemagglutinin was isolated from tubers of Colocasia esculenta cv. 'Small Taro' by employing a purification protocol that involved ion…”
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A lectin with highly potent inhibitory activity toward breast cancer cells from edible tubers of Dioscorea opposita cv. nagaimo by Chan, Yau Sang, Ng, Tzi Bun

“…A 70-kDa galactose-specific lectin was purified from the tubers of Dioscorea opposita cv. nagaimo. The purification involved three chromatographic steps: anion…”
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Marine lectins and their medicinal applications by Cheung, Randy Chi Fai, Wong, Jack Ho, Pan, Wenliang, Chan, Yau Sang, Yin, Cuiming, Dan, Xiuli, Ng, Tzi Bun

“…Marine organisms have been extensively explored for the last several decades as potential sources of novel biologically active compounds, and extensive…”
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Lectins with anti-HIV activity: a review by Akkouh, Ouafae, Ng, Tzi Bun, Singh, Senjam Sunil, Yin, Cuiming, Dan, Xiuli, Chan, Yau Sang, Pan, Wenliang, Cheung, Randy Chi Fai

“…Lectins including flowering plant lectins, algal lectins, cyanobacterial lectins, actinomycete lectin, worm lectins, and the nonpeptidic lectin mimics…”
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An Update of Lectins from Marine Organisms: Characterization, Extraction Methodology, and Potential Biofunctional Applications by Ahmmed, Mirja Kaizer, Bhowmik, Shuva, Giteru, Stephen G., Zilani, Md. Nazmul Hasan, Adadi, Parise, Islam, Shikder Saiful, Kanwugu, Osman N., Haq, Monjurul, Ahmmed, Fatema, Ng, Charlene Cheuk Wing, Chan, Yau Sang, Asadujjaman, Md, Chan, Gabriel Hoi Huen, Naude, Ryno, Bekhit, Alaa El-Din Ahmed, Ng, Tzi Bun, Wong, Jack Ho

“…Lectins are a unique group of nonimmune carbohydrate-binding proteins or glycoproteins that exhibit specific and reversible carbohydrate-binding activity in a…”
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Isolation of a glucosamine binding leguminous lectin with mitogenic activity towards splenocytes and anti-proliferative activity towards tumor cells by Chan, Yau Sang, Wong, Jack Ho, Fang, Evandro Fei, Pan, Wenliang, Ng, Tzi Bun

“…A dimeric 64-kDa glucosamine-specific lectin was purified from seeds of Phaseolus vulgaris cv. "brown kidney bean." The simple 2-step purification protocol…”
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Lectins from edible mushrooms by Singh, Senjam Sunil, Wang, Hexiang, Chan, Yau Sang, Pan, Wenliang, Dan, Xiuli, Yin, Cui Ming, Akkouh, Ouafae, Ng, Tzi Bun

“…Mushrooms are famous for their nutritional and medicinal values and also for the diversity of bioactive compounds they contain including lectins. The present…”
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Antifungal and antiviral products of marine organisms by Cheung, Randy Chi Fai, Wong, Jack Ho, Pan, Wen Liang, Chan, Yau Sang, Yin, Cui Ming, Dan, Xiu Li, Wang, He Xiang, Fang, Evandro Fei, Lam, Sze Kwan, Ngai, Patrick Hung Kui, Xia, Li Xin, Liu, Fang, Ye, Xiu Yun, Zhang, Guo Qing, Liu, Qing Hong, Sha, Ou, Lin, Peng, Ki, Chan, Bekhit, Adnan A, Bekhit, Alaa El-Din, Wan, David Chi Cheong, Ye, Xiu Juan, Xia, Jiang, Ng, Tzi Bun

“…Marine organisms including bacteria, fungi, algae, sponges, echinoderms, mollusks, and cephalochordates produce a variety of products with antifungal activity…”
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Bioactive Proteins in Panax notoginseng Roots and Other Panax Species by Chan, Yau Sang, Wong, Jack Ho, Ng, Tzi Bun

“…The genus Panax consists of a group of prized medicinal herbs. Major members of the Panax genus include P. ginseng, P. notoginseng, P. quinquefolius, and P…”
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Trichosanthin inhibits breast cancer cell proliferation in both cell lines and nude mice by promotion of apoptosis by Fang, Evandro Fei, Zhang, Chris Zhi Yi, Zhang, Lin, Wong, Jack Ho, Chan, Yau Sang, Pan, Wen Liang, Dan, Xiu Li, Yin, Cui Ming, Cho, Chi Hin, Ng, Tzi Bun

“…Breast cancer ranks as a common and severe neoplasia in women with increasing incidence as well as high risk of metastasis and relapse. Translational and…”
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A hemagglutinin isolated from Northeast China black beans induced mitochondrial dysfunction and apoptosis in colorectal cancer cells by Dan, Xiuli, Ng, Tzi Bun, Wong, Jack Ho, Chan, Yau Sang, Cheung, Randy Chi Fai, Chan, Wai Yee

“…Incidence of colorectal cancer is closely related with the lifestyle, especially the dietary habits of patients. Epidemiological researches have demonstrated a…”
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Brown Kidney Bean Bowman–Birk Trypsin Inhibitor is Heat and pH Stable and Exhibits Anti-proliferative Activity by Chan, Yau Sang, Zhang, Yanbo, Ng, Tzi Bun

“…A trypsin inhibitor with a molecular mass around 17 kDa was purified from the seeds of Phaseolus vulgaris cv. ‘brown kidney bean’. The purification protocol…”
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Momordica Charantia lectin, a type II ribosome inactivating protein, exhibits antitumor activity toward human nasopharyngeal carcinoma cells in vitro and in vivo by Fang, Evandro Fei, Zhang, Chris Zhi Yi, Ng, Tzi Bun, Wong, Jack Ho, Pan, Wen Liang, Ye, Xiu Juan, Chan, Yau Sang, Fong, Wing Ping

“…The incidence of nasopharyngeal carcinoma (NPC) remains high in endemic regions, including southern China, northern Africa, and North America. One of the…”
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Snake venom toxins: toxicity and medicinal applications by Chan, Yau Sang, Cheung, Randy Chi Fai, Xia, Lixin, Wong, Jack Ho, Ng, Tzi Bun, Chan, Wai Yee

“…Snake venoms are complex mixtures of small molecules and peptides/proteins, and most of them display certain kinds of bioactivities. They include neurotoxic,…”
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Apoptosis and Anti-cancer Drug Discovery: The Power of Medicinal Fungi and Plants by Wong, Jack Ho, Sze, Stephen Cho Wing, Ng, Tzi Bun, Cheung, Randy Chi Fai, Tam, Chit, Zhang, Kalin Yanbo, Dan, Xiuli, Chan, Yau Sang, Cho, William Chi Shing, Ng, Charlene Cheuk Wing, Waye, Mary Miu Yee, Liang, Weicheng, Zhang, Jinfang, Yang, Jie, Ye, Xiuyun, Lin, Juan, Ye, Xiujuan, Wang, Hexiang, Liu, Fang, Chan, David Wai, Ngan, Hextan Yuen Sheung, Sha, Ou, Li, Guohui, Tse, Ryan, Tse, Tak Fu, Chan, Helen

“…The purpose of this account is to review the compounds capable of eliciting mitochondria-mediated apoptosis in cancer cells produced by medicinal fungi and…”
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