Search Results - "Chan, Wei Xuan"
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1
Cardiac forces regulate zebrafish heart valve delamination by modulating Nfat signaling
Published in PLoS biology (14-01-2022)“…In the clinic, most cases of congenital heart valve defects are thought to arise through errors that occur after the endothelial-mesenchymal transition…”
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2
Strategies for multi-case physics-informed neural networks for tube flows: a study using 2D flow scenarios
Published in Scientific reports (21-05-2024)“…Fluid dynamics computations for tube-like geometries are crucial in biomedical evaluations of vascular and airways fluid dynamics. Physics-Informed Neural…”
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3
Cardiac motion estimation from medical images: a regularisation framework applied on pairwise image registration displacement fields
Published in Scientific reports (28-10-2020)“…Accurate cardiac motion estimation from medical images such as ultrasound is important for clinical evaluation. We present a novel regularisation layer for…”
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4
Mechanical Effects of Cochlear Implant on Acoustic Hearing
Published in IEEE transactions on biomedical engineering (01-06-2019)“…Residual hearing loss in cochlear implant users is investigated using the mechanical-human-cochlear model. Hearing loss due to stiffening of the round window…”
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5
Effects of Hypertrophic and Dilated Cardiac Geometric Remodeling on Ejection Fraction
Published in Frontiers in physiology (31-05-2022)“…Background: Both heart failure (HF) with preserved ejection fraction (HFpEF) and heart failure with reduced ejection fraction (HFrEF) can present a wide…”
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6
Micro-ultrasonic welding using thermoplastic-elastomeric composite film
Published in Journal of materials processing technology (01-10-2016)“…A composite film of PMMA microspheres in PDMS is used as the fusion layer to avoid trapped air and to restrict the flow of the melted polymer during welding…”
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7
Understanding Interdependencies between Mechanical Velocity and Electrical Voltage in Electromagnetic Micromixers
Published in Micromachines (Basel) (29-06-2020)“…Micromixers are critical components in the lab-on-a-chip or micro total analysis systems technology found in micro-electro-mechanical systems. In general, the…”
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8
Diagnostic and prognostic value of an ejection fraction adjusted for myocardial remodeling
Published in Frontiers in cardiovascular medicine (2024)“…Ejection fraction (EF) is widely used to evaluate heart function during heart failure (HF) due to its simplicity compared but it may misrepresent cardiac…”
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9
Computational efficiency of meshfree methods with local-coordinates algorithm
Published in International journal of precision engineering and manufacturing (01-03-2015)“…In this study, meshfree methods with uniform nodal distribution and local-coordinates shape functions are investigated. The proposed meshfree method can be…”
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10
Empirical and biophysical estimations of human cochlea’s psychophysical tuning curve sharpness
Published in AIP advances (01-01-2016)“…Despite the advances in cochlear research, the estimation of auditory nerve fiber frequency tuning of human cochlea is mostly based on psychophysical…”
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11
Study of concentric, eccentric and split type magnetic membrane micro-mixers
Published in Sensing and Bio-Sensing Research (01-06-2018)“…Electromagnetically driven elastic magnetic microfluidic mixers were investigated for their performance in air, water and glycerol filled chambers. They were…”
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12
Pre-intervention myocardial stress is a good predictor of aortic valvoluplasty outcome for fetal critical aortic stenosis and evolving HLHS
Published in The Journal of physiology (01-02-2024)“…Fetal critical aortic stenosis with evolving hypoplastic left heart syndrome (CAS-eHLHS) causes biomechanical and functional aberrations, leading to a high…”
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13
Pre‐intervention myocardial stress is a good predictor of aortic valvuloplasty outcome for fetal critical aortic stenosis and evolving HLHS
Published in The Journal of physiology (15-02-2024)“…Fetal critical aortic stenosis with evolving hypoplastic left heart syndrome (CAS‐eHLHS) causes biomechanical and functional aberrations, leading to a high…”
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14
Myocardial biomechanical effects of fetal aortic valvuloplasty
Published in Biomechanics and modeling in mechanobiology (01-10-2024)“…Fetal critical aortic stenosis with evolving hypoplastic left heart syndrome (CAS-eHLHS) can progress to a univentricular (UV) birth malformation…”
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15
Biventricular finite element modeling of the fetal heart in health and during critical aortic stenosis
Published in Biomechanics and modeling in mechanobiology (01-08-2024)“…Finite Element simulations are a robust way of investigating cardiac biomechanics. To date, it has only been performed with the left ventricle (LV) alone for…”
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16
Full cardiac cycle asynchronous temporal compounding of 3D echocardiography images
Published in Medical image analysis (01-12-2021)“…•We performed 3D asynchronous temporal compounding of echocardiography images via cardiac motion estimation. Images frames from the entire cardiac cycle is…”
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17
Role of tissue biomechanics in the formation and function of myocardial trabeculae in zebrafish embryos
Published in The Journal of physiology (01-02-2024)“…Cardiac trabeculae are uneven ventricular muscular structures that develop during early embryonic heart development at the outer curvature of the ventricle…”
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18
Morphological, functional, and biomechanical progression of LV remodelling in a porcine model of HFpEF
Published in Journal of biomechanics (01-11-2022)“…Heart failure (HF) with preserved ejection fraction (HFpEF) accounts for about half of heart failure cases, but the progression of cardiac biomechanics during…”
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19
Organ Dynamics and Hemodynamic of the Whole HH25 Avian Embryonic Heart, Revealed by Ultrasound Biomicroscopy, Boundary Tracking, and Flow Simulations
Published in Scientific reports (02-12-2019)“…Congenital heart malformations occur to substantial number of pregnancies. Studies showed that abnormal flow biomechanical environments could lead to…”
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20
Fluid mechanics of the left atrial ligation chick embryonic model of hypoplastic left heart syndrome
Published in Biomechanics and modeling in mechanobiology (01-08-2021)“…Left atrial ligation (LAL) of the chick embryonic heart at HH21 is a model of the hypoplastic left heart syndrome (HLHS) disease, demonstrating morphological…”
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