Search Results - "Chan, Wai‐Ling"

Peptide Inhibitors of West Nile NS3 Protease:  SAR Study of Tetrapeptide Aldehyde Inhibitors by Knox, John E, Ma, Ngai Ling, Yin, Zheng, Patel, Sejal J, Wang, Wei-Ling, Chan, Wai-Ling, Ranga Rao, K. R, Wang, Gang, Ngew, Xinyi, Patel, Viral, Beer, David, Lim, Siew Pheng, Vasudevan, Subhash G, Keller, Thomas H

“…A series of inhibitors related to the benzoyl-norleucine-lysine-arginine-arginine (Bz-nKRR) tetrapeptide aldehyde was synthesized. When evaluated against the…”
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Angiographic and clinical outcomes of everolimus-eluting stent in the treatment of extra long stenoses (AEETES) by Jim, Man-Hong, Yiu, Kai-Hang, Ho, Hee-Hwa, Chan, Wai-Ling, Ng, Andrew Kei-Yan, Siu, Chung-Wah, Chow, Wing-Hing

“…The purpose of this study was to examine the angiographic and clinical results of stent full metal jacket in treating long lesions using everolimus-eluting…”
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Discovery of Dengue Virus NS4B Inhibitors by Wang, Qing-Yin, Dong, Hongping, Zou, Bin, Karuna, Ratna, Wan, Kah Fei, Zou, Jing, Susila, Agatha, Yip, Andy, Shan, Chao, Yeo, Kim Long, Xu, Haoying, Ding, Mei, Chan, Wai Ling, Gu, Feng, Seah, Peck Gee, Liu, Wei, Lakshminarayana, Suresh B, Kang, CongBao, Lescar, Julien, Blasco, Francesca, Smith, Paul W, Shi, Pei-Yong

“…The four serotypes of dengue virus (DENV-1 to -4) represent the most prevalent mosquito-borne viral pathogens in humans. No clinically approved vaccine or…”
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adenosine nucleoside inhibitor of dengue virus by Yin, Zheng, Chen, Yen-Liang, Schul, Wouter, Wang, Qing-Yin, Gu, Feng, Duraiswamy, Jeyaraj, Kondreddi, Ravinder Reddy, Niyomrattanakit, Pornwaratt, Lakshminarayana, Suresh B, Goh, Anne, Xu, Hao Ying, Liu, Wei, Liu, Boping, Lim, Joanne Y.H, Ng, Chuan Young, Qing, Min, Lim, Chin Chin, Yip, Andy, Wang, Gang, Chan, Wai Ling, Tan, Hui Pen, Lin, Kai, Zhang, Bo, Zou, Gang, Bernard, Kristen A, Garrett, Christine, Beltz, Karen, Dong, Min, Weaver, Margaret, He, Handan, Pichota, Arkadius, Dartois, Veronique, Keller, Thomas H, Shi, Pei-Yong

“…Dengue virus (DENV), a mosquito-borne flavivirus, is a major public health threat. The virus poses risk to 2.5 billion people worldwide and causes 50 to 100…”
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Lead Optimization of Spiropyrazolopyridones: A New and Potent Class of Dengue Virus Inhibitors by Zou, Bin, Chan, Wai Ling, Ding, Mei, Leong, Seh Yong, Nilar, Shahul, Seah, Peck Gee, Liu, Wei, Karuna, Ratna, Blasco, Francesca, Yip, Andy, Chao, Alex, Susila, Agatha, Dong, Hongping, Wang, Qing Yin, Xu, Hao Ying, Chan, Katherine, Wan, Kah Fei, Gu, Feng, Diagana, Thierry T, Wagner, Trixie, Dix, Ina, Shi, Pei-Yong, Smith, Paul W

“…Spiropyrazolopyridone 1 was identified, as a novel dengue virus (DENV) inhibitor, from a DENV serotype 2 (DENV-2) high-throughput phenotypic screen. As a…”
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Inhibition of Dengue Virus RNA Synthesis by an Adenosine Nucleoside by Chen, Yen-Liang, Yin, Zheng, Duraiswamy, Jeyaraj, Schul, Wouter, Lim, Chin Chin, Liu, Boping, Xu, Hao Ying, Qing, Min, Yip, Andy, Wang, Gang, Chan, Wai Ling, Tan, Hui Pen, Lo, Melissa, Liung, Sarah, Kondreddi, Ravinder Reddy, Rao, Ranga, Gu, Helen, He, Handan, Keller, Thomas H, Shi, Pei-Yong

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Peptide inhibitors of dengue virus NS3 protease. Part 1: Warhead by Yin, Zheng, Patel, Sejal J., Wang, Wei-Ling, Wang, Gang, Chan, Wai-Ling, Rao, K.R. Ranga, Alam, Jenefer, Jeyaraj, Duraiswamy A., Ngew, Xinyi, Patel, Viral, Beer, David, Lim, Siew Pheng, Vasudevan, Subhash G., Keller, Thomas H.

“…Substrate-based tetrapeptide inhibitors with various warheads were designed, synthesized, and evaluated against the Dengue virus NS3 protease. Effective…”
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Structural Variations Identified in Patients with Autism Spectrum Disorder (ASD) in the Chinese Population: A Systematic Review of Case-Control Studies by Chair, Sek-Ying, Chow, Ka-Ming, Chan, Cecilia Wai-Ling, Chan, Judy Yuet-Wa, Law, Bernard Man-Hin, Waye, Mary Miu-Yee

“…Autistic spectrum disorder (ASD) is a neurodevelopmental disability characterised by the impairment of social interaction and communication ability. The…”
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N-Sulfonylanthranilic Acid Derivatives as Allosteric Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase by Yin, Zheng, Chen, Yen-Liang, Kondreddi, Ravinder Reddy, Chan, Wai Ling, Wang, Gang, Ng, Ru Hui, Lim, Joanne Y. H, Lee, Wan Yen, Jeyaraj, Duraiswamy A, Niyomrattanakit, Pornwaratt, Wen, Daying, Chao, Alex, Glickman, J. Fraser, Voshol, Hans, Mueller, Dieter, Spanka, Carsten, Dressler, Sigmar, Nilar, Shahul, Vasudevan, Subhash G, Shi, Pei-Yong, Keller, Thomas H

“…A novel class of compounds containing N-sulfonylanthranilic acid was found to specifically inhibit dengue viral polymerase. The structural requirements for…”
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Serial Bone Scintigraphy in a Case of Malignant Epithelioid Hemangioendothelioma by Swainson, Ian, Chan, Wai-Ling, Abbati, Donna

“…Epithelioid hemangioendothelioma (EHE) of the bone is a rare vascular tumor. It accounts for less than 1% of all malignant bone tumors and usually follows an…”
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Discovery of Tetrahydropyrazolopyrimidine Carboxamide Derivatives As Potent and Orally Active Antitubercular Agents by Yokokawa, Fumiaki, Wang, Gang, Chan, Wai Ling, Ang, Shi Hua, Wong, Josephine, Ma, Ida, Rao, Srinivasa P S, Manjunatha, Ujjini, Lakshminarayana, Suresh B, Herve, Maxime, Kounde, Cyrille, Tan, Bee Huat, Thayalan, Pamela, Ng, Seow Hwee, Nanjundappa, Mahesh, Ravindran, Sindhu, Gee, Peck, Tan, Maria, Wei, Liu, Goh, Anne, Chen, Pei-Yu, Lee, Kok Sin, Zhong, Chen, Wagner, Trixie, Dix, Ina, Chatterjee, Arnab K, Pethe, Kevin, Kuhen, Kelli, Glynne, Richard, Smith, Paul, Bifani, Pablo, Jiricek, Jan

“…Tetrahydropyrazolo[1,5-a]pyrimidine scaffold was identified as a hit series from a Mycobacterium tuberculosis (Mtb) whole cell high through-put screening (HTS)…”
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Peptide deformylase inhibitors of Mycobacterium tuberculosis: Synthesis, structural investigations, and biological results by Pichota, Arkadius, Duraiswamy, Jeyaraj, Yin, Zheng, Keller, Thomas H., Alam, Jenefer, Liung, Sarah, Lee, Gladys, Ding, Mei, Wang, Gang, Chan, Wai Ling, Schreiber, Mark, Ma, Ida, Beer, David, Ngew, Xinyi, Mukherjee, Kakoli, Nanjundappa, Mahesh, Teo, Jeanette W.P., Thayalan, Pamela, Yap, Amelia, Dick, Thomas, Meng, Wuyi, Xu, Mei, Koehn, James, Pan, Shi-Hao, Clark, Kirk, Xie, Xiaoling, Shoen, Carolyn, Cynamon, Michael

“…Bacterial peptide deformylase (PDF) belongs to a subfamily of metalloproteases catalyzing the removal of the N-terminal formyl group from newly synthesized…”
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Dual-time-point (18)F-FDG-PET/CT imaging in the assessment of suspected malignancy by Chan, Wai-Ling, Ramsay, Stuart C, Szeto, Edwin R, Freund, Judith, Pohlen, Judith M, Tarlinton, Lisa C, Young, Andy, Hickey, Adam, Dura, Robert

“…INTRODUCTION (PURPOSE OF THE STUDY): The objective of this study was to assess whether dual-time-point (18)F-fluoro-2-deoxyglucose ((18)F-FDG)-PET/CT imaging…”
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Yellow fever virus NS3 protease: peptide-inhibition studies by Lohr, Kristina, Knox, John E, Phong, Wai Yee, Ma, Ngai Ling, Yin, Zheng, Sampath, Aruna, Patel, Sejal J, Wang, Wei-Ling, Chan, Wai-Ling, Rao, K. R. Ranga, Wang, Gang, Vasudevan, Subhash G, Keller, Thomas H, Lim, Siew Pheng

“…Novartis Institute for Tropical Diseases, 10 Biopolis Road, #05-01 Chromos, Singapore 138670 Correspondence Siew Pheng Lim siew_pheng.lim{at}novartis.com A…”
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Peptide inhibitors of dengue virus NS3 protease. Part 2: SAR study of tetrapeptide aldehyde inhibitors by Yin, Zheng, Patel, Sejal J., Wang, Wei-Ling, Chan, Wai-Ling, Ranga Rao, K.R., Wang, Gang, Ngew, Xinyi, Patel, Viral, Beer, David, Knox, John E., Ma, Ngai Ling, Ehrhardt, Claus, Lim, Siew Pheng, Vasudevan, Subhash G., Keller, Thomas H.

“…With the aim of discovering potent and selective dengue NS3 protease inhibitors, we systematically synthesized and evaluated a series of tetrapeptide aldehydes…”
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Dual-time-point 18F-FDG-PET/CT imaging in the assessment of suspected malignancy by Chan, Wai-Ling, Ramsay, Stuart C, Szeto, Edwin R, Freund, Judith, Pohlen, Judith M, Tarlinton, Lisa C, Young, Andy, Hickey, Adam, Dura, Robert

“…Introduction (purpose of the study): The objective of this study was to assess whether dual‐time‐point 18F‐fluoro‐2‐deoxyglucose (18F‐FDG)‐PET/CT imaging…”
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Challenges to the infant care profession: practitioners' perspectives by Chan, Wai Ling

“…This paper explored the challenges to the infant care profession in Hong Kong crèches, with an aim to contribute to the existing early childhood care…”
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Effectiveness of the SIME Program for Infants and Toddlers in Center-Based Settings by Zhang, Xiao, Chan, Wai Ling

“…Objective: This study evaluates the effectiveness of a center-based childcare program, namely, the stimulation, interaction, motivation, and experience (SIME)…”
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The discrepancy between teachers' beliefs and practices: a study of kindergarten teachers in Hong Kong by Chan, Wai Ling

“…This study examines the discrepancy between teachers' beliefs and practices in Hong Kong kindergartens and the factors that influence this discrepancy. Three…”
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Teacher-child relationship quality and Chinese toddlers’ developmental functioning: A cross-lagged modelling approach by Liu, Ting, Zhang, Xiao, Zhao, Kun, Chan, Wai Ling

“…•Teacher–child relationships predicted and were predicted by toddlers’ comprehension and personal-social skills.•Teacher-child relationships predicted but were…”
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